A5057647904- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Fetal and Pediatric Neurological Disorders
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Congenital Diaphragmatic Hernia Studies
- Urological Disorders and Treatments
- Neonatal Respiratory Health Research
- Gestational Diabetes Research and Management
- Neonatal and fetal brain pathology
- Parvovirus B19 Infection Studies
- Ovarian cancer diagnosis and treatment
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Neonatal Health and Biochemistry
- Congenital Heart Disease Studies
- Gestational Trophoblastic Disease Studies
- Mycobacterium research and diagnosis
- Reproductive Biology and Fertility
- Gynecological conditions and treatments
- Maternal and Perinatal Health Interventions
- Hernia repair and management
- Tumors and Oncological Cases
- Prenatal Substance Exposure Effects
At Bristol
2023
Magee-Womens Hospital
1998-2016
University of Pittsburgh
2001-2016
University of Pittsburgh Medical Center
2002
Magee-Womens Research Institute
1996
Children's Hospital of Pittsburgh
1991-1994
Mayo Clinic
1977-1986
Mayo Clinic in Arizona
1983
University of Manitoba
1981
University of Southern California
1979-1981
Screening for aneuploid pregnancies is routinely performed after 15 weeks of gestation and has a sensitivity approximately 65 percent, with false positive rate 5 percent. First-trimester markers aneuploidy have been developed, but their use in combination not adequately evaluated clinical practice.We conducted multicenter study screening trisomies 21 18 among patients between 74 97 days gestation, based on maternal age, levels free beta human chorionic gonadotropin pregnancy-associated...
Abstract Objective To describe the process of training for measuring nuchal translucency at five clinical centers in North America and to evaluate methods quality assurance feedback Design Throughout a period 18 months, performance sonographers fetal was monitored using qualitative quantitative review. After 12 different approaches (written personal feedback) were used inform technical aspects that needed or could be improved. Results On initial review, discrepancies judgment from reviewers...
To determine whether an association exists between the severity of polyhydramnios and frequency preterm delivery.The study group consisted 275 singleton pregnancies with as defined by amniotic fluid index (AFI) at least 25 cm. Polyhydramnios was arbitrarily categorized into three groups severity: mild (AFI 25-30 cm), moderate 30.1-35 severe greater than 35.1 cm). A delivery considered if it occurred before 37 weeks' gestation.Fifty-two (18.9%) women delivered gestation. Preterm in 199...
2267 singleton fetuses who had one ultrasound examination between 15 and 21 weeks' gestation were prospectively evaluated for echogenic small bowel. Thirty-two cases of bowel detected--a prevalence 1.4 per cent. Echogenic fetal was divided into two grades: grade 1, where the more than liver; 2, echogenicity bone. In contrast to 19/23 with 1 echogenicity, only 2/9 2 a normal pregnancy outcome (Fisher's exact test; P < or = 0.01). Complications associated second-trimester included in utero...
Sixty-one instances of congenital anomalies identified prenatally by ultrasound were reviewed to determine whether autopsy provided important additional information. An finding was defined as one which would affect: 1) genetic counseling; 2) diagnosis a syndrome; 3) determination etiology or pathogenetic mechanism the anomaly; 4) interpretation severity anomalies. In 28 cases (46%), post-mortem examination such All these infants had multiple anomalies; correlations with oligohydramnios and...
This manuscript reviews congenital anomalies and imaging findings associated with non-visualisation of the cavum septi pellucidi (CSP) found on prenatal sonogram.Observation a normal is an important landmark in second third trimester ultrasound evaluation fetal brain, its visualisation provides reassurance central forebrain development. Non-visualisation CSP sonographic finding, which most cases neuroanatomical that include agenesis corpus callosum, schizencephaly, septo-optic dysplasia,...
To determine the reliability of first trimester sonography in detection twin chorionicity and amnionicity.Sets twins (179) were evaluated sonographically trimester. Chorionicity was determined by identifying number gestational sacs. The presence or absence an amnion about each embryo/fetus also recorded. placentas for case to amnionicity.Of 179 pairs, 158 dichorionic/diamniotic; 19 monochorionic/diamniotic, two pairs monochorionic/monoamniotic. amnionicity correctly case.The pregnancies can...
Abstract The pregnancy outcome of 347 patients with a confirmed, viable intrauterine between 6.0 and 14.0 weeks, menstrual age, was determined. miscarriage rate 4.2% in subgroup without vaginal bleeding, as compared 12.7% bleeding (χ 2 = 7.4, p < 0.006). First trimester significant covariate the determination spontaneous after fetal cardiac activity has been confirmed.
After studying 4024 consecutive patients at a gestational age of 28 weeks or older, the prevalence breech presentation was found to be 24.4%. By 37 weeks, number presentations had decreased 3.7%.
To estimate and compare the risk of morbid perinatal outcomes in pregnancies identified as small for gestational age (SGA) with customized compared conventional standards fetal growth.Ultrasound-derived estimates weight were used to generate a growth trajectory (N=7,510). The at delivery pathologic physiologic variables from 5,072 calculate threshold SGA. In separate analysis 32,070 pregnancies, rates participants classified SGA according population-based birth standard only (SGApop only),...
Abstract Objective The objective of this article is to determine the success rate prenatally diagnosed isolated aqueductal stenosis (AS) as a first step in an evidence‐based reassessment ventriculoamniotic shunting for AS. Methods Cases ventriculomegaly at Magee‐Womens Hospital between 2006 and 2013 were ascertained. AS was suspected when prenatal ultrasound magnetic resonance imaging (MRI) demonstrated signs pressure hydrocephalus. diagnosis generated by MRI compared with postnatal based...
To evaluate the possibility of fetal compensatory renal hypertrophy with a unilateral functioning kidney.A nomogram length was established from 254 normal fetuses. Renal also obtained in 14 fetuses agenesis and 22 multicystic kidney.Compensatory hypertrophy, defined as > 95th percentile for gestational age, occurred 16 36 cases (44.4%).Compensatory is detectable utero may occur early weeks' gestation.