A5100381425- Bioenergy crop production and management
- Biofuel production and bioconversion
- Plant Genetic and Mutation Studies
- Chronic Lymphocytic Leukemia Research
- Cancer, Lipids, and Metabolism
- Phytochemistry and Bioactive Compounds
- Oral Health Pathology and Treatment
- Inflammatory mediators and NSAID effects
- Inflammasome and immune disorders
- Advancements in Transdermal Drug Delivery
- Acute Myeloid Leukemia Research
- Diagnosis and Treatment of Venous Diseases
- Pressure Ulcer Prevention and Management
- Rheumatoid Arthritis Research and Therapies
- Immunodeficiency and Autoimmune Disorders
- Cutaneous lymphoproliferative disorders research
- Nanoplatforms for cancer theranostics
- Assisted Reproductive Technology and Twin Pregnancy
- Ferroptosis and cancer prognosis
- Reproductive System and Pregnancy
- Head and Neck Cancer Studies
- Psoriasis: Treatment and Pathogenesis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
First Affiliated Hospital of Jiangxi Medical College
2025
Jiangxi Provincial People's Hospital
2025
Central South University
2025
Lanzhou University
2024
Lanzhou University Second Hospital
2024
Hunan University
2023
Qingdao University
2023
Xuzhou Central Hospital
2023
Shenzhen Children's Hospital
2023
Xuzhou Medical College
2023
Cardiovascular diseases (CVDs) pose a significant threat to human health due the high mortality and morbidity rates. Traditional drugs often have limited efficacy inherent constraints, such as low bioavailability notable side effects. As highly regarded therapeutic strategy, nanotechnology offers new perspectives means for treating CVDs. Nanozyme-based targeted specifically address biological processes in areas affected by CVDs, thereby achieving precise treatment. Compared traditional...
Psoriasis is a chronic inflammatory skin disease that difficult to treat. Quercetin (QT) dietary flavonoid known for its anti-inflammatory effects and safe use in humans. However, the topical application of quercetin psoriasis treatment presents significant challenge due poor water solubility low stability semisolid preparations, where it tends recrystallize. This work novel liposome-in-gel formulation quercetin-based psoriasis. The quercetin-loading liposomes are stabilized by...
Objective Psychiatric patients are particularly vulnerable to skin injuries, which can result in severe systemic complications and higher mortality rates. Therefore, improving wound management for ICU psychiatric through Failure Mode Effects Analysis (FMEA) is crucial. This study aims evaluate the effectiveness of FMEA enhancing settings, with a focus on identifying key risk factors implementing targeted interventions mitigate complications. Methods A real-world was conducted Fourth People’s...
In patients with hematologic malignancies, the combination of triazole antifungals and vincristine can lead to severe neurological toxicity. We attempted assess adverse events (AEs) associated these interactions, particularly ileus. retrieved AEs data from FAERS database (2004-2023) focusing on four triazoles (fluconazole, itraconazole, voriconazole, posaconazole) vincristine. Case reports were collected for retrospective analysis up 31 December 2023. The indicated that gastrointestinal...
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease that lacks effective treatment modalities. Once patients are diagnosed with IPF, their median survival approximately 3-5 years. PPARγ an important target for the prevention and of fibrosis. Asarinin lignan compound can be extracted from food plant Asarum heterotropoides. In this study, we investigated therapeutic effects asarinin in model constructed using bleomycin mice explored underlying mechanisms....
Gouty arthritis (GA) is an inflammatory disorder that associated with elevated serum levels of uric acid. Total saponins from Dioscorea nipponica Makino (TSDN) are a natural component ameliorates inflammation while also decreasing acid levels. The aim the present study was to unravel mechanism TSDN in gouty rats regard regulation formation neutrophil extracellular traps (NETs) via PI3K/AKT/mTOR axis. A total 40 Wistar were divided into 4 groups: normal, model, and rapamycin groups....
BackgroundThe efficacy and safety of the oral Janus kinase inhibitor peficitinib were investigated in Asian patients with rheumatoid arthritis (RA).MethodsIn this double-blind, phase 3 study, from mainland China, Korea, Taiwan RA an inadequate response/intolerance to methotrexate randomized (1:1:1) once-daily placebo (N = 128), 100 mg 129), or 150 128) combination non-biologic DMARDs. At Week 24, receiving switched mg. American College Rheumatology (ACR) 20 response at 24/early termination...
To investigate the clinical and endocrine risk factors for pregnancy loss in women with abnormal glucose/lipid metabolism a history of loss, to develop predictive model assess these women's subsequent pregnancies.
Background In vitro fertilization (IVF) is the main technique to address infertility issue in patient-oriented strategy encompassing individualized oocyte number (POSEIDON) population. Adopting appropriate protocols for assisted reproduction technologies (ART) cycles POSEIDON group may attain more favorable pregnancy outcomes. Objectives This study aimed compare effectiveness of modified long gonadotropin-releasing hormone agonist protocol and non-downregulation patients undergoing ART,...
Abstract Background This study aims to identify a novel cuproptosis-related model using comprehensive bioinformatics analysis, which will offer new insights into hepatocellular carcinoma (HCC) classification. Additionally, it seeks comprehensively analyze the correlation between risk score and various aspects, including prognosis, tumor mutation burden (TMB), biological function, microenvironment (TME), immune efficacy of HCC. Methods In this study, we integrated HCC gene expression profile...
Although Streptococcus constellatus (SC), an opportunistic pathogen, can cause abscesses and empyema. The SC infection after vertebral augmentation (VA) interfere with patients' daily living activities be life-threatening in severe cases. A 67-year-old male complained of lumbar pain for two months. patient underwent percutaneous vertebroplasty the second third vertebrae months ago. On admission, laboratory imaging evidence suggested bilateral psoas major left lumbodorsal abscesses. After...
BACKGROUND The prevalence of multiple primary malignant neoplasms (MPMNs) is increasing in parallel with the incidence malignancies, continual improvement diagnostic models, and extended life patients tumors, especially those digestive system. However, co-existence MPMNs duodenal adenocarcinoma (DA) rarely reported. In addition, there a lack comprehensive analysis regarding multi-omics tumor microenvironment (TME). CASE SUMMARY this article, we report case 56-year-old man who presented...