A5072545226- Protein Hydrolysis and Bioactive Peptides
- Plant-Microbe Interactions and Immunity
- Enzyme Production and Characterization
- Fungal and yeast genetics research
- Plant Virus Research Studies
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Phytase and its Applications
- Insect Utilization and Effects
- Plant and Fungal Interactions Research
- Drug Transport and Resistance Mechanisms
- Electrocatalysts for Energy Conversion
- Identification and Quantification in Food
- Supercapacitor Materials and Fabrication
- Adrenal Hormones and Disorders
- Catalytic Processes in Materials Science
- Photosynthetic Processes and Mechanisms
- Meat and Animal Product Quality
- Adsorption and biosorption for pollutant removal
- Robotics and Sensor-Based Localization
- Biochemical effects in animals
- Peroxisome Proliferator-Activated Receptors
- Fuel Cells and Related Materials
- Vibrio bacteria research studies
- Nanoparticle-Based Drug Delivery
Southwest University
2025
Tongji University
2023-2025
Army Medical University
2024
Southwest Hospital
2024
Shihezi University
2009-2024
Yancheng Institute of Technology
2024
University of Liverpool
2020-2023
Guangdong Food and Drug Vocational College
2023
Korea Maritime and Ocean University
2022
Central South University
2016-2022
Compartmentalization is a ubiquitous building principle in cells, which permits segregation of biological elements and reactions. The carboxysome specialized bacterial organelle that encapsulates enzymes into virus-like protein shell plays essential roles photosynthetic carbon fixation. naturally designed architecture, semi-permeability, catalytic improvement carboxysomes have inspired rational design engineering new nanomaterials to incorporate desired the for enhanced performance. Here, we...
Doxorubicin is one of the most widely used chemotherapy agents for treatment breast cancer. However, development doxorubicin resistance limits long‑term benefits in patients with Curcumin, a well‑known dietary polyphenol derived from rhizomes turmeric (Curcuma longa), enhances sensitivity cancer cells to chemotherapeutic agents; however, mechanisms underlying this phenomenon remain unclear. The aim present study was evaluate effect curcumin on chemoresistance doxorubicin‑resistant...
Hydrogenases are microbial metalloenzymes capable of catalyzing the reversible interconversion between molecular hydrogen and protons with high efficiency, have great potential in development new electrocatalysts for renewable fuel production. Here, we engineered intact proteinaceous shell carboxysome, a self-assembling protein organelle CO2 fixation cyanobacteria proteobacteria, sequestered heterologously produced [NiFe]-hydrogenases into carboxysome shell. The protein-based hybrid catalyst...
The nitrogen (N) cycle is closely related to the stability of marine ecosystems. Microbial communities have been directly linked N-cycling processes. However, systematic research on bacterial community composition and diversity involved in N cycles different seas lacking. In this study, microbial Bohai Sea (BHS), Yellow (YS) South China (SCS) was surveyed by targeting hypervariable V4 regions 16S rRNA gene using next-generation sequencing (NGS) technology. A total 2,505,721 clean reads...
The carboxysome is a protein-based nanoscale organelle in cyanobacteria and many proteobacteria, which encapsulates the key CO2-fixing enzymes ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) carbonic anhydrase (CA) within polyhedral protein shell. intrinsic self-assembly architectural features of carboxysomes semipermeability shell provide foundation for accumulation CO2 enhanced carboxylation. Here, we develop an approach to determine interior pH conditions inorganic carbon...
High-grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy mainly due to its extensive metastasis. Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3), a newly discovered splice variant of solute carrier transporter family member (SLCO1B3), has been reported be overexpressed in several types cancer. However, biological function Ct-OATP1B3 remains largely unknown. Here, we reveal that HGSOC and promotes metastasis vivo vitro. Mechanically, directly...
Bacterial extracellular proteases from six strains of marine bacteria and seven terrestrial were prepared through fermentation. Proteases analyzed substrate immersing zymography used to hydrolyze the collagen muscle proteins a salmon skin byproduct, respectively. Collagen could be degraded much more easily than protein, but it commonly showed weaker antioxidant capability. The hydrolysate was with crude enzymes Pseudoalteromonas sp. SQN1 displayed strongest activity in DPPH hydroxyl radical...
This study employed a straightforward, environmentally friendly spontaneous reduction technique to fabricate nano Pd-CeO2 catalysts simply on nickel foam (NF). The Pd-CeO2/NF sample exhibited remarkable catalytic activity towards methanol oxidation in an alkaline environment, achieving current density of 971.6 mA/cm2 and retaining 78.2% its initial after 2000 seconds, demonstrating exceptional durability. research contributes novel strategies the advancement highly efficient catalysts.
Simultaneous Localization and Mapping (SLAM) technology has garnered significant interest in the robotic vision community over past few decades. The rapid development of SLAM resulted its widespread application across various fields, including autonomous driving, robot navigation, virtual reality. Although SLAM, especially Visual–Inertial (VI-SLAM), made substantial progress, most classic algorithms this field are designed based on assumption that observed scene is static. In complex...
Collagenases are the most important group of commercially-produced enzymes. However, even though biological resources abundant in sea, very few these commercially popular enzymes from marine sources, especially bacteria. We optimized production collagenases by Pseudoalteromonas sp. SJN2 and investigated antioxidant activities hydrolysates. Media components culture conditions associated with collagenase were statistical methods, namely Plackett-Burman design response surface methodology...
Microbial communities in sediments play an important role alpine lake ecosystems. However, the microbial diversity and community composition of from Hengduan Mountains remain largely unknown. Therefore, based on Illumina MiSeq platform, high-throughput sequencing analysis 16S rRNA gene was performed 15 collected at different locations Mountains. The abundance-based coverage estimate (ACE), Chao1, Shannon indices indicated that abundance these were high. There are some differences among...
Long-term monitoring and recognition of underwater organism objects are great significance in marine ecology, fisheries science many other disciplines. Traditional techniques this field, including manual fishing-based ones sonar-based ones, usually flawed. Specifically, the method based on fishing is time-consuming unsuitable for scientific researches, while one, has defects low acoustic image accuracy large echo errors. In recent years, rapid development deep learning its excellent...
The bacterial prepeptidase C-terminal (PPC) domain can be found in the C termini of a wide variety proteases that are secreted by marine bacteria. However, functions these PPC domains remain unknown due to lack systematic research. Here, binding and swelling abilities eight from six different were compared systematically via scanning electron microscopy (SEM), enzyme assays, fluorescence spectroscopy. These all possess ability bind swell insoluble collagen. expose collagen monomers but...
The study reported on the isolation of a metalloprotease named EH2 from Pseudoalteromonas sp. H2. maintained more than 80% activity over wide pH range 5-10, and stability was also nearly independent pH. Over 65% detected at temperature 20-70 °C. high protease in presence different surfactants oxidizing agents observed. Moreover, we investigated antioxidant activities hydrolysates generated porcine salmon skin collagen by EH2. results showed that demonstrated higher DPPH...