A5077198405- Analytical Chemistry and Chromatography
- Crystallization and Solubility Studies
- Drug Solubulity and Delivery Systems
- Supramolecular Chemistry and Complexes
- Material Properties and Processing
- Microfluidic and Capillary Electrophoresis Applications
- Supramolecular Self-Assembly in Materials
- Engineering Education and Pedagogy
- X-ray Diffraction in Crystallography
- Luminescence and Fluorescent Materials
- Lipid Membrane Structure and Behavior
- Microfluidic and Bio-sensing Technologies
- Spectroscopy and Quantum Chemical Studies
- Rheology and Fluid Dynamics Studies
- Surfactants and Colloidal Systems
- Photoreceptor and optogenetics research
- Music Technology and Sound Studies
Louisiana State University
2023-2024
Bavarian Polymer Institute
2019
University of Würzburg
2019
Despite decades of research, our understanding the molecular interactions between drugs and polymers in drug-loaded polymer micelles does not extend much beyond concepts such as "like-dissolves-like" or hydrophilic/hydrophobic. However, polymer–drug compatibility strongly affects formulation properties therefore translation a into clinics. Specific hydrogen-bonding, π–π stacking, coordination can be utilized to increase drug loading. This is commonly based on trial error eventually leads an...
This work presents an automatic extruder as a research experience for undergraduate students. The system offers user-friendly approach to preparing vesicles, such liposomes or polymersomes, with defined size and polydispersity-properties crucial in biology macromolecules. It comprises two syringe pumps connected by membrane filter. setup is controlled software. Compared manual extrusion, this automated provides advantages, precisely variables. project describes tool enhance learning science...
<p></p><p>Despite decades of research, our understanding the molecular interactions between drugs and polymers in drug loaded polymer micelles does not extend much beyond concepts such as “like-dissolves-like“ or hydrophilic/hydrophobic. However, polymer-drug compatibility strongly affects formulation properties therefore translation a into clinics. Specific hydrogen-bonding, π-π stacking coordination can be utilized to increase drug-loading. This is commonly based on...
A well-rounded introduction to work in a STEM laboratory is vital scientific education. Besides the ability use available instrumentation for sample characterization, students should also be imparted knowledge steps of instrument development and construction. These concepts can taught using example lipid vesicle preparation via extrusion. Vesicle extrusion common technique that involves syringes pushing solutions through membrane filters used fundamental studies on vesicles. Such research...
Despite intense research, methods for controlling soft matter's spontaneous self-assembly into well-defined layers remain a significant challenge. We observed ion-induced structural discontinuities of phospholipid vesicles that can be exploited controlled materials, using DOPC and NaCl as model system. The observations were made the 0.25 wt % lipid concentration. used dynamic light scattering, zeta-potential measurement, cryo-electron microscopy, small-angle X-ray, neutron scattering to...
Despite decades of research, our understanding the molecular interactions between drugs and polymers in drug loaded polymer micelles does not extend much beyond concepts such as “like-dissolves-like“ or hydrophilic/hydrophobic. However, polymer-drug compatibility strongly affects formulation properties therefore translation a into clinics. Specific hydrogen-bonding, π-π stacking coordination can be utilized to increase drug-loading. This is commonly based on trial-and-error eventually leads...
Light-activated molecular motors rotate at a similar frequency in polymersomes and solution.