A5052290998- Photodynamic Therapy Research Studies
- Cancer, Hypoxia, and Metabolism
- Porphyrin and Phthalocyanine Chemistry
- Nanoplatforms for cancer theranostics
- Metal complexes synthesis and properties
MIREA - Russian Technological University
2023-2024
Chemotherapy is among the main classical approaches to treatment of oncologic diseases. Its efficiency has been comprehensively proven by clinical examinations; however, low selectivity chemotherapeutic agents limits possibilities this method, making it necessary search for new therapy Photodynamic least invasive method and a very efficient alternative malignant tumors; its depends on depth light penetration into tissue degree oxygenation zone. In work, hitherto unknown conjugate natural...
Combined therapy is currently a popular method for increasing the efficiency of antitumor treatment. It involves use two different tumor treatment methods, namely, chemotherapy and PDT. Combining cytotoxic agent photosensitizer in single molecule results synergistic effect that overcomes multiple drug resistance reduces therapeutic doses. In this work, pyridine-containing natural chlorins were obtained by introducing pyridine group into 13 1 -[Formula: see text]-(4-aminobutyl)amide chlorin...