A5012072318- MicroRNA in disease regulation
- Congenital Diaphragmatic Hernia Studies
- Virus-based gene therapy research
- Fibroblast Growth Factor Research
- Congenital Anomalies and Fetal Surgery
- Connective Tissue Growth Factor Research
- Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- RNA modifications and cancer
- Kruppel-like factors research
- Oropharyngeal Anatomy and Pathologies
- Circular RNAs in diseases
- Neonatal Respiratory Health Research
- Cleft Lip and Palate Research
Guangzhou Medical University
2013-2024
Guangzhou University of Chinese Medicine
2024
Connective tissue growth factor (CTGF) has different roles in types of cancer. However, the involvement and molecular basis CTGF tumor progression prognosis human nasopharyngeal carcinoma (NPC) have almost never been reported. In this study, we observed that downregulated expression was significantly associated with NPC poor prognosis. Knockdown markedly elevated ability cell proliferation vivo vitro. Subsequently, discovered reduction increased miR-18b, an oncomir-promoting proliferation....
To assess the value of chromosome microarray analysis (CMA) for identifying etiology patients with congenital cleft lip and palate.Twenty-two no identifiable chromosomal aberrations by conventional cytogenetic technique were selected. DNA was extracted hybridized Affymetrix CytoScan(TM) HD arrays following manufacturer's protocol. The data analyzed a CHAS v2.0 software.CMA has identified submicroscopic copy number variants (CNVs) in all cases, which have ranged from 100 kb to 1.8 Mb....
Abstract To investigate the role and mechanism of miR-342 FOXP1 on hepatocellular carcinoma cells. QRT-PCR was applied to determine expression miR-342, MYCBP in normal hepatocyte cell lines (NHC), (HEK-293 T) human (HepG2, MHCC97-L, Huh7 SMMC7721). After knockdown or over-expression HepG2 cells respectively, proliferation viability were measured using MTT assay colony formation assay. Flow cytometry adopted test for apoptosis. Dual luciferase gene reporter assays performed validate target...