- Retinal Development and Disorders
- Photoreceptor and optogenetics research
- Helminth infection and control
- Parasite Biology and Host Interactions
- Optical Network Technologies
- Neuroscience and Neuropharmacology Research
- Advanced Optical Network Technologies
- Nicotinic Acetylcholine Receptors Study
- Parasites and Host Interactions
- Advanced Fluorescence Microscopy Techniques
- Advanced Steganography and Watermarking Techniques
- Study of Mite Species
- Internet Traffic Analysis and Secure E-voting
- Semiconductor Lasers and Optical Devices
- Aquatic Invertebrate Ecology and Behavior
- Caching and Content Delivery
- Advanced Photonic Communication Systems
- Radiation Effects and Dosimetry
- Genetic diversity and population structure
- Radiation Therapy and Dosimetry
- Network Packet Processing and Optimization
- Security in Wireless Sensor Networks
- User Authentication and Security Systems
- Image and Video Quality Assessment
- Cell Adhesion Molecules Research
Tencent (China)
2021-2024
Yale University
2012-2023
Beijing University of Posts and Telecommunications
2010
Hunan University
2007
National Institute for Parasitic Diseases
2001-2006
Chinese Center For Disease Control and Prevention
2005
Retinal bipolar cells (BCs) transmit visual signals in parallel channels from the outer to inner retina, where they provide glutamatergic inputs specific networks of amacrine and ganglion cells. Intricate network computation at BC axon terminals has been proposed as a mechanism for complex computation, such direction selectivity, but direct knowledge receptive field property synaptic connectivity various types is required order understand role axonal by BCs. The present study tested...
Retinal waves are correlated bursts of spontaneous activity whose spatiotemporal patterns critical for early activity-dependent circuit elaboration and refinement in the mammalian visual system. Three separate developmental wave epochs or stages have been described, but mechanism(s) pattern generation each their distinct roles development remain incompletely understood. We used neuroanatomical, vitro vivo electrophysiological, optical imaging techniques genetically manipulated mice to...
Spontaneous activity during early development is necessary for the formation of precise neural connections, but it remains uncertain whether plays an instructive or permissive role in brain wiring. In visual system, retinal ganglion cell (RGC) projections to form two prominent sensory maps, one reflecting eye origin and other retinotopic location. Recent studies provide compelling evidence supporting spontaneous eye-specific projections, a similarly retinotopy more equivocal. Here, we report...
Significance Retinal vGluT3 amacrine cells (GACs) release glutamate and glycine to enhance suppress contrast/motion sensitivity, respectively. GACs' relatively compact size diffuse ramification pattern suggest global dendritic processing of visual signals across ON OFF sublayers the inner plexiform layer. Surprisingly, we find that signal spread in GAC dendrites is limited both vertical lateral dimensions. Vertical restriction preserves fundamental ON-OFF segregation scheme, while enables...
A novel robust watermarking algorithm based on the second-LSB (least significant bit) is proposed. The first groups data by hash value of primary key and positions with in every group. watermark not directly embedded one single item, but bit into group setting a pseudo-random number to LSB data. threshold, which used for detection be compared occurrence frequency positioned embedding, set according distribution probabilities Without affecting usability data, scattered databases evenly hard...
Wireless sensor networks are self-organized and data-centric. Security is a critical issue in many applications. In order to protect the security of data, we propose novel secure transmission strategy based on information hiding (IH). this design, acquire sensitive securely so as make use advantage IH technique without encryption. Our approach deal with weakness limitation node resources threats, it suitable for stream data nodes. The simulation experiments also demonstrate that effective...
Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation. However, this frequently requires relatively high laser powers. Here, we developed a novel strategy that improve the efficiency of current stimulation technologies positioning fluorescent proteins or small molecules cross-sections in vicinity opsins. This generates highly localized source endogenous single-photon illumination tailored to match optimal opsin absorbance. Through neuronal and vascular...
Abstract Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation; however, this frequently requires relatively high laser powers or holographic illumination. Here we developed a practical strategy to improve the efficiency of stimulation positioning fluorescent proteins small molecules cross-sections in vicinity opsins. This generates highly localized source endogenous single-photon illumination that tailored match optimal opsin absorbance. Through...
Efficient video transcoding has become a critical technology in content delivery network (CDN) service for social networked application. In this paper, we propose data-driven parallel solution CDN. The key to the is compute ranking of popular videos through web log analysis and then transcode by mapreduce. Experimental results show that our can significantly improve efficiency transcoding.
A novel robust watermarking algorithm based on the second-LSB (least significant bit) is proposed. The first groups data by hash value of primary key and positions with in every group. watermark not directly embedded one single item, but bit into group setting a pseudo-random number to LSB data. threshold, which used for detection be compared occurrence frequency positioned embedding, set according distribution probabilities Without affecting usability data, scattered databases evenly hard...
M1 intrinsically photosensitive retinal ganglion cells (ipRGCs) are known to encode absolute light intensity (irradiance) for non-image-forming visual functions (subconscious vision), such as circadian photoentrainment and the pupillary reflex. It remains unclear how respond relative (contrast) patterned signals. The present study identified a special form of contrast sensitivity (suppressed-by-contrast) in cells, suggesting role signals regulating vision potential ipRGCs encoding...
Purpose: To develop a simple model that fully utilizes the information of 4DCT and accurately incorporates priori knowledge patient motion into plan optimization evaluation in 4D radiotherapy. Methods Materials: We IMRT as two independent schemes, beamlet dose calculation scheme weights updating scheme. All is encoded A used to calculate associated with each phase. Deformable registration determines voxel‐to‐voxel map from arbitrary phase reference phase, which respiration modeled...
A multi-dimensional EDFA gain spectrum optimization scheme based on the penalty method with gradient descent is proposed to increase capacity of a WDM system. 5.47% achieved in simulations.