Minggang Chen

ORCID: 0009-0002-2493-1902
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About
Contact & Profiles
Research Areas
  • Retinal Development and Disorders
  • Photoreceptor and optogenetics research
  • Helminth infection and control
  • Parasite Biology and Host Interactions
  • Optical Network Technologies
  • Neuroscience and Neuropharmacology Research
  • Advanced Optical Network Technologies
  • Nicotinic Acetylcholine Receptors Study
  • Parasites and Host Interactions
  • Advanced Fluorescence Microscopy Techniques
  • Advanced Steganography and Watermarking Techniques
  • Study of Mite Species
  • Internet Traffic Analysis and Secure E-voting
  • Semiconductor Lasers and Optical Devices
  • Aquatic Invertebrate Ecology and Behavior
  • Caching and Content Delivery
  • Advanced Photonic Communication Systems
  • Radiation Effects and Dosimetry
  • Genetic diversity and population structure
  • Radiation Therapy and Dosimetry
  • Network Packet Processing and Optimization
  • Security in Wireless Sensor Networks
  • User Authentication and Security Systems
  • Image and Video Quality Assessment
  • Cell Adhesion Molecules Research

Tencent (China)
2021-2024

Yale University
2012-2023

Beijing University of Posts and Telecommunications
2010

Hunan University
2007

National Institute for Parasitic Diseases
2001-2006

Chinese Center For Disease Control and Prevention
2005

Retinal bipolar cells (BCs) transmit visual signals in parallel channels from the outer to inner retina, where they provide glutamatergic inputs specific networks of amacrine and ganglion cells. Intricate network computation at BC axon terminals has been proposed as a mechanism for complex computation, such direction selectivity, but direct knowledge receptive field property synaptic connectivity various types is required order understand role axonal by BCs. The present study tested...

10.1152/jn.00283.2014 article EN Journal of Neurophysiology 2014-07-17

Retinal waves are correlated bursts of spontaneous activity whose spatiotemporal patterns critical for early activity-dependent circuit elaboration and refinement in the mammalian visual system. Three separate developmental wave epochs or stages have been described, but mechanism(s) pattern generation each their distinct roles development remain incompletely understood. We used neuroanatomical, vitro vivo electrophysiological, optical imaging techniques genetically manipulated mice to...

10.1523/jneurosci.3549-15.2016 article EN cc-by-nc-sa Journal of Neuroscience 2016-03-30

Spontaneous activity during early development is necessary for the formation of precise neural connections, but it remains uncertain whether plays an instructive or permissive role in brain wiring. In visual system, retinal ganglion cell (RGC) projections to form two prominent sensory maps, one reflecting eye origin and other retinotopic location. Recent studies provide compelling evidence supporting spontaneous eye-specific projections, a similarly retinotopy more equivocal. Here, we report...

10.1002/dneu.22288 article EN Developmental Neurobiology 2015-03-18

Significance Retinal vGluT3 amacrine cells (GACs) release glutamate and glycine to enhance suppress contrast/motion sensitivity, respectively. GACs' relatively compact size diffuse ramification pattern suggest global dendritic processing of visual signals across ON OFF sublayers the inner plexiform layer. Surprisingly, we find that signal spread in GAC dendrites is limited both vertical lateral dimensions. Vertical restriction preserves fundamental ON-OFF segregation scheme, while enables...

10.1073/pnas.1711622114 article EN Proceedings of the National Academy of Sciences 2017-09-27

A novel robust watermarking algorithm based on the second-LSB (least significant bit) is proposed. The first groups data by hash value of primary key and positions with in every group. watermark not directly embedded one single item, but bit into group setting a pseudo-random number to LSB data. threshold, which used for detection be compared occurrence frequency positioned embedding, set according distribution probabilities Without affecting usability data, scattered databases evenly hard...

10.1109/ias.2007.25 article EN 2007-08-01

Wireless sensor networks are self-organized and data-centric. Security is a critical issue in many applications. In order to protect the security of data, we propose novel secure transmission strategy based on information hiding (IH). this design, acquire sensitive securely so as make use advantage IH technique without encryption. Our approach deal with weakness limitation node resources threats, it suitable for stream data nodes. The simulation experiments also demonstrate that effective...

10.1109/mobiq.2007.4451044 article EN 2007-01-01

Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation. However, this frequently requires relatively high laser powers. Here, we developed a novel strategy that improve the efficiency of current stimulation technologies positioning fluorescent proteins or small molecules cross-sections in vicinity opsins. This generates highly localized source endogenous single-photon illumination tailored to match optimal opsin absorbance. Through neuronal and vascular...

10.1016/j.isci.2023.107857 article EN cc-by-nc-nd iScience 2023-09-09

Abstract Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation; however, this frequently requires relatively high laser powers or holographic illumination. Here we developed a practical strategy to improve the efficiency of stimulation positioning fluorescent proteins small molecules cross-sections in vicinity opsins. This generates highly localized source endogenous single-photon illumination that tailored match optimal opsin absorbance. Through...

10.1101/2020.06.29.179077 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-06-30

Efficient video transcoding has become a critical technology in content delivery network (CDN) service for social networked application. In this paper, we propose data-driven parallel solution CDN. The key to the is compute ranking of popular videos through web log analysis and then transcode by mapreduce. Experimental results show that our can significantly improve efficiency transcoding.

10.1109/cscloud/edgecom.2018.00042 article EN 2018-06-01

A novel robust watermarking algorithm based on the second-LSB (least significant bit) is proposed. The first groups data by hash value of primary key and positions with in every group. watermark not directly embedded one single item, but bit into group setting a pseudo-random number to LSB data. threshold, which used for detection be compared occurrence frequency positioned embedding, set according distribution probabilities Without affecting usability data, scattered databases evenly hard...

10.1109/isias.2007.4299789 article EN 2007-08-01

M1 intrinsically photosensitive retinal ganglion cells (ipRGCs) are known to encode absolute light intensity (irradiance) for non-image-forming visual functions (subconscious vision), such as circadian photoentrainment and the pupillary reflex. It remains unclear how respond relative (contrast) patterned signals. The present study identified a special form of contrast sensitivity (suppressed-by-contrast) in cells, suggesting role signals regulating vision potential ipRGCs encoding...

10.1113/jp281717 article EN The Journal of Physiology 2021-07-22

Purpose: To develop a simple model that fully utilizes the information of 4DCT and accurately incorporates priori knowledge patient motion into plan optimization evaluation in 4D radiotherapy. Methods Materials: We IMRT as two independent schemes, beamlet dose calculation scheme weights updating scheme. All is encoded A used to calculate associated with each phase. Deformable registration determines voxel‐to‐voxel map from arbitrary phase reference phase, which respiration modeled...

10.1118/1.2240874 article EN Medical Physics 2006-06-01

A multi-dimensional EDFA gain spectrum optimization scheme based on the penalty method with gradient descent is proposed to increase capacity of a WDM system. 5.47% achieved in simulations.

10.1364/networks.2021.nef1b.5 article EN OSA Advanced Photonics Congress 2021 2021-01-01
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