A5101755192- Crystal Structures and Properties
- Retinal Development and Disorders
- Photoreceptor and optogenetics research
- Nonlinear Optical Materials Research
- Cellular transport and secretion
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Epigenetics and DNA Methylation
- Magnetic Properties and Applications
- Solid-state spectroscopy and crystallography
- Neuroscience and Neuropharmacology Research
- Iron-based superconductors research
- Zebrafish Biomedical Research Applications
- Advanced Fluorescence Microscopy Techniques
- Hearing, Cochlea, Tinnitus, Genetics
- Hippo pathway signaling and YAP/TAZ
- Structural Behavior of Reinforced Concrete
- Protein Degradation and Inhibitors
- Genetics, Aging, and Longevity in Model Organisms
- Dermatological and Skeletal Disorders
- Power Transformer Diagnostics and Insulation
- Chromatin Remodeling and Cancer
- Genetic and rare skin diseases.
- Skin and Cellular Biology Research
- Induction Heating and Inverter Technology
Huashan Hospital
2023-2024
Fudan University
2023-2024
State Key Laboratory of Medical Neurobiology
2023-2024
China Three Gorges University
2020-2024
Nankai University
2024
Beijing Academy of Quantum Information Sciences
2024
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2024
Yangzhou University
2021-2023
Zhengzhou University
2020-2023
Shanghai Jiao Tong University
2019
The chirality-dependent lattice distortion assisted by a crown ether leads to an intense STEs emission along with CPL. distinct endows the Sb halides multi-stimuli-responsive PL behaviours towards excitation wavelength and temperature.
Abstract Background Microbial cell population heterogeneity is now recognized as a major source of issues in the development and optimization bioprocesses. Even if single technologies are available for study microbial heterogeneity, only few these methods order to dynamics segregation directly bioreactors. In this context, specific interfaces have been developed connect flow cytometer bioreactor automated analyses. work, we propose simplified version such an interface demonstrate its...
Soft tissue engineering has been seeking ways to mimic the natural extracellular microenvironment that allows cells migrate and proliferate regenerate new tissue. Therefore, reconstruction of soft requires a scaffold possessing matrix (ECM)-mimicking fibrous structure elastic property, which affect cell functions regeneration. Herein, an effective method for fabricating nanofibrous hydrogel is demonstrated using gelatin–hydroxyphenylpropionic acid (Gel–HPA) by electrospinning enzymatic...
Biomechanical stimuli derived from the extracellular matrix (ECM) extremely tune stem cell fate through 3D and spatiotemporal changes in vivo. The stiffness is a crucial factor during bone tissue development. However, most vitro models to study osteogenesis of mesenchymal cells (MSCs) are static or stiffening 2D environment. Here, dynamic controllable biomimetic model created regulate osteogenic differentiation MSCs with dual-functional gelatin macromer that can generate double-network...
Context: Temporal lobe epilepsy (TLE) is resistant to antiepileptic drugs (AEDs) and associated with cognitive impairment. The modern Chinese medicine, compound Danshen dripping pills (CDDP), clinically effective in treating improving impairment.Objective: This study evaluated the protective effects of CDDP alone combination carbamazepine (CBZ) on kainic acid-induced TLE impairment rats.Materials methods: Sprague–Dawley rats were randomly divided into five groups: control (sham operated),...
In the past few decades, many new infrared (IR) second-order nonlinear optical (NLO) materials have been prepared by various synthetic methods to satisfy growing market demand. However, ones high potentials be applicable since their comprehensive NLO properties cannot meet standards, which include a series of indicators like large effects, laser-induced damage thresholds (LIDTs), phase matchability, thermal stability, good growth habit, and so on. Considering available IR materials'...
Abstract Disseminated superficial porokeratosis (DSP) is a rare keratinization disorder of the epidermis. It characterized by keratotic lesions with an atrophic center encircled prominent peripheral ridge. We investigated genetic basis DSP in two five-generation Chinese families members diagnosed DSP. By whole-exome sequencing, we sequencing identified nonsense variation c.412C > T (p.Arg138*) phosphomevalonate kinase gene ( PMVK ), which encodes cytoplasmic enzyme catalyzing conversion...
A series of pentanary chalcogenoborates (A3X)[InB12(InQ4)3] (A = K, Rb, Cs; X Cl, Br, I; Q S, Se) were obtained by high-temperature solid-state reactions. These salt-inclusion chalcogenides crystallize in the hexagonal space group P6322, a type Kleinman-forbidden noncentrosymmetric structure. Their structures feature [InB12(InQ4)3] open framework built InQ6 octahedra and InQ4 tetrahedra consolidated B12 cluster, which accomodates octahedral cavities for XA6 units. They are second-harmonic...
Second-order nonlinear optical (NLO) materials are extensively applied in laser-related techniques. For developing IR NLO materials, chalcogenides the main candidates. Here, NaGa3Se5 was explored as inspired by its unique anionic structure. It crystallizes with orthorhombic chiral P212121 structure, featuring 12 types of GaSe4 tetrahedra built into a three-dimensional {[Ga3Se5]-}∞ network, representing new NLO-functional motif. exhibits large and phase-matchable response 1.37 × AgGaS2. has...
Rare-earth (RE) chalcogenide borates are very rarely discovered in view of the difficulties synthesis though they have demonstrated attractive physical performances. Here, first mixed RE Eu5.4Sm3.6MgS2B20O41 (1) and Eu3Gd6MgS2B20O41 (2) synthesized by combining RE, sulfur, borate ions into one structure. They crystallize centrosymmetric hexagonal space group P63/m, their 3D honeycomb-like {[B20O41]22-}∞ open frameworks built [B6O9(O0.5)6]6- [B7O13(O0.5)3]8- polyanionic clusters consolidated...
Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation. However, this frequently requires relatively high laser powers. Here, we developed a novel strategy that improve the efficiency of current stimulation technologies positioning fluorescent proteins or small molecules cross-sections in vicinity opsins. This generates highly localized source endogenous single-photon illumination tailored to match optimal opsin absorbance. Through neuronal and vascular...
Hematopoietic stem and progenitor cells (HSPCs) have the ability to self-renew differentiate into various blood cells, thus playing an important role in maintenance of lifelong hematopoiesis. Brahma-related gene 1 (BRG1), which acts as ATP subunit mammalian SWI-SNF-related chromatin remodeling complexes, is involved human acute myeloid leukemia highly expresses short-term HSPCs. But its regulatory mechanism for HSPC development not yet been well established. Here, we generated a brg1...
In this paper, a coupled flow-thermal field simulation model is established based on the parameters of transformer. Then distribution flow and thermal fields are obtained. The results show that oil backflow occurs to varying degrees at top bottom addition, with formation backflow, hot spot temperature transformer increases. Through combination orthogonal experiments finite element method, geometric structure winding passage selected as optimization variable. law between maximum acquired by...
Both borates and sulfides are important inorganic multifunctional materials. Encouraged by this background, thioborates attract considerable interest. However, their investigations highly hindered the scarcity of available ones synthetic difficulty new ones. Here, we report a thioborate KEu2In3B12S13 (1), which was obtained via facile solid-state reaction in KI flux. It crystallizes trigonal R3̄m structure, three-dimensional structure features six InS6 octahedron consolidated B12 icosahedron...
Tumor necrosis factor alpha (TNF-α) is a crucial in the control of Mycobacterium tuberculosis ( Mtb ) infection. Pathogenic mycobacteria can inhibit and/or regulate host cell TNF-α production variety ways to evade antituberculosis (anti-TB) immunity as well facilitate immune escape. However, mechanisms by which expression cells modulated benefit still an interesting topic and needs further study. Here, we report that macrophages infected with marinum Mm )—a close relative —upregulated E3...
In this paper, a fluid‐thermal coupled finite element model is established based on the design parameters of dry‐type core reactor, detailed temperature distribution results are given, and heat transfer process layer coils was analyzed. Meanwhile, electromagnetic characteristics reactor have been analyzed, it shows that structure adjustment little effect inductance reactor. Taking metal conductor usage as optimization object, dissipation between air ducts equivalent to vertical pipe,...
A novel thioborate KNa 0.78 Eu 0.27 In 3.80 B 12 S features {[In ] 2.6− } ∞ framework built by clusters and InS x ( = 4, 5, 6) units. Its structural chemistry is well described, compared with known compounds containing Q cluster.
In this paper, according to the parameters of dry type air core smoothing reactor, stress‐sound field and fluid‐temperature coupling simulation model is established, detailed temperature sound distribution are obtained, influence law arrester on pressure level rise analyzed. It can be found that encapsulation coils significantly increased when adding arrester, reasons given by analyzing fluid velocity in ducts. Meanwhile, optimization design method about proposed based orthogonal experiment...
Optical nonlinearities are one of the most fascinating properties two-dimensional (2D) materials. While tremendous efforts have been made to find and optimize second-order optical nonlinearity in enormous 2D materials, opportunities explore higher-order ones elusive because much lower efficiency. Here, we report giant high odd-order centrosymmetric correlated van der Waals insulator manganese phosphorus triselenide. When illuminated by two near-infrared femtosecond lasers, sample generates a...
Real-time approaches are typically needed in studies of learning and memory, vivo calcium imaging provides the possibility to investigate neuronal activity awake animals during behavior tasks. Since hippocampus is closely associated with episodic spatial it has become an essential brain region this field's research. In recent research, engram cells place were studied by recording neural activities hippocampal CA1 using miniature microscope mice while performing behavioral tasks including...