A5100453759- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Lipoproteins and Cardiovascular Health
- Epigenetics and DNA Methylation
- Plant Molecular Biology Research
- Circular RNAs in diseases
- Genetic Mapping and Diversity in Plants and Animals
- Healthcare professionals’ stress and burnout
- Parasite Biology and Host Interactions
- GABA and Rice Research
- Parasites and Host Interactions
- Neurological Disease Mechanisms and Treatments
- Genomic variations and chromosomal abnormalities
- Cerebrovascular and Carotid Artery Diseases
- Diversity and Career in Medicine
- RNA Research and Splicing
- Medical Education and Admissions
- Identification and Quantification in Food
- Dental Anxiety and Anesthesia Techniques
- Advanced Proteomics Techniques and Applications
- COVID-19 and Mental Health
- Salmonella and Campylobacter epidemiology
- Plant Taxonomy and Phylogenetics
Hezhou University
2023-2024
Yuxi Normal University
2024
Case Western Reserve University
2023
Changzhi Medical College
2009-2022
Affiliated Hospital of Southwest Medical University
2021
Chinese Academy of Agricultural Sciences
2015-2020
Institute of Crop Sciences
2015-2020
First Affiliated Hospital of Sichuan Medical University
2020
Hebei General Hospital
2019
Zhejiang University
2017
Sorghum, an African grass related to sugar cane and maize, is grown for food, feed, fibre fuel. We present initial analysis of the ∼730-megabase Sorghum bicolor (L.) Moench genome, placing ∼98% genes in their chromosomal context using whole-genome shotgun sequence validated by genetic, physical syntenic information. Genetic recombination largely confined about one-third sorghum genome with gene order density similar those rice. Retrotransposon accumulation recombinationally recalcitrant...
This study aimed to analyze the potential function of lncRNA CCAT2 in cervical cancer cell proliferation and apoptosis.Expression level lines (HeLa, CaSki, SiHa) was detected by quantitative real-time PCR. knockdown established transfecting siRNA into human cells. Its effects on were studied using cell-counting kit-8 assay. The effect cells cycle apoptosis assessed flow cytometry assay.CCK8 assay showed that inhibited HeLa, SiHa confirmed results could induce G1 phase arrestment trigger...
// Lin Yu 1 , Lina Tai Lifang Zhang Yi Chu Yixing Li and Lei Zhou State Key Laboratory for Conservation Utilization of Subtropical Agro-Bioresources, College Animal Science Technology, Guangxi University, Nanning, P.R. China Correspondence to: Li, email: liyixing39@163.com Zhou, zhoulei@gxu.edu.cn Keywords: lncRNA, pig, obesity, QTL Received: April 28, 2017 Accepted: May 15, Published: 26, 2017 ABSTRACT Objectives: Current studies have revealed that long...
Heading date (HD) and panicle length (PL) are important traits that affect rice breeding controlled by pleiotropic genes. Some alleles associated with HD PL from wild relatives might differ those in cultivated rice. In this study, a main effect quantitative trait locus rice, qHD7.2, was identified using chromosomal segment substitution line (CSSL) population. First, qHD7.2 determined to be located near RM172 on chromosome 7 based association analysis of phenotype data six environments 181...
Abstract Due to the remarkable adaptability various environments, rice varieties with diverse flowering times have been domesticated or improved from Oryza rufipogon . Detailed knowledge of genetic factors controlling time will facilitate understanding adaptation mechanism in cultivated and enable breeders design appropriate genotypes for distinct preferences. In this study, four genes ( Hd1 , DTH8 Ghd7 OsPRR37 ) a long‐day suppression pathway were collected sequenced 154, 74, 69 62 sativa...
Aberrantly expressed microRNAs contribute to the initiation and progression of human cancer. MiRNA-187 has been reported in nasopharyngeal, renal, pancreatic, prostate, esophageal cancer, acts as a tumor suppressor or oncogene. However, underlying function miRNA-187 cervical cancer remains largely unexplored. In present study, we demonstrated significantly down-regulation tissues cell lines compared their normal counterparts. Kaplan-Meier analysis revealed that decreased was closely...
The effects of the expression a small heat shock protein (shsp) gene from Streptococcus thermophilus on stress resistance in Lactococcus lactis under different environmental stresses were investigated this study. pMG36e-shsp, an vector, was first constructed by inserting shsp open reading frame (ORF) cloned S. strain St-QC into pMG36e. Then, food-grade pMG-shsp, generated deleting erythromycin pMG36e-shsp. transformation rate pMG-shsp comparable to that pMG36e-shsp when each these two...
Growing cultivated rice with a moderate heading date is the key to expanding its cultivation area and maintaining stable yields. The genes that regulates are largely cloned; however, it remains unclear how genetic mutations their combinations affect adaptability of rice. Here, we report analysis variation in eight long-day flowering suppressor (Hd1, DTH8, Ghd7, OsCOL4, DTH7, Hd6, Se5, PhyB) phylogenetic relationship genes. Genetic variations Hd1, PhyB OsCOL4 correlated differences...
Abstract Background The undergraduate program of psychiatry has been widely established in recent years to improve the education and recruitment psychiatrists China. We aim investigate career choice medical students majoring China influential factors. Method This multicenter study was conducted 26 schools from May October 2019. Participants included 4610 3857 clinical medicine. Multivariable logistic regression used factors students’ choices at matriculation as a career. Results 44.08%...
Autophagy is essential in lens organelle degradation. This study aimed to seek potential autophagy-associated long noncoding RNAs (lncRNAs) and their relative mechanisms human development using the "fried egg" lentoid body (LB) generation system. The expression pattern of LC3B differentiating LBs was similar that developing a mouse vivo. Among massive lncRNAs expressed with significant difference between induced pluripotent stem cells (iPSCs) LBs, lncRNA affecting (ALB), which predicted have...
Abstract Background MicroRNA (miRNA), which is short non-coding RNA, plays a pivotal role in the regulation of many biological processes and affects stability and/or translation mRNA. Recently, machine learning algorithms were developed to predict potential miRNA targets. Most these methods are robust but not sensitive redundant or irrelevant features. Despite their good performance, relative importance each feature still unclear. With increasing experimental data becoming available,...
Emerging studies demonstrate that single nucleotide polymorphisms (SNPs) resided in the microRNA recognition element seed sites (MRESSs) 3′UTR of mRNAs are putative biomarkers for human diseases and cancers. However, exhaustively experimental validation causality MRESS SNPs is impractical. Therefore bioinformatics have been introduced to predict causal SNPs. Genome-wide association study (GWAS) provides a way detect susceptibility millions simultaneously by taking linkage disequilibrium (LD)...
This study was to explore the application of MRI based on artificial intelligence technology combined with neuropsychological assessment cognitive impairment patients neurological cerebrovascular diseases. A total 176 were divided into a control group, vascular non-dementia (VCIND) dementia (VD) and an Alzheimer's disease (AD) group. All underwent evaluation examination, improved fuzzy C-means (FCM) clustering algorithm proposed for processing. It found that segmentation accuracy (SA)...
Anoikis is a specific form of programmed cell death induced by loss contact between cells and extracellular matrices or other cells. Only tumor that are resistant to anoikis can survive in the state detachment from primary tissue during early stages metastasis. The ability resist crucial for cancer ILF2 proto-oncogene previously studied glioma, NSCLC, esophageal pancreatic ductal carcinoma. results present study revealed transcription factor interleukin enhancer-binding 2 (ILF2) was highly...
Arterial hypertension is considered the most prevalent risk factor for stroke. Both pathophysiologic and clinical data previously acquired suggest a strong correlation between hemodynamic nature of arterial an increase in ischemic insult to tissues. However, knowledge specific molecular interactions stroke (IS) limited. In this study, we performed systematic bioinformatics analysis stroke-prone spontaneous hypertensive brain tissue samples rats (GSE41452), middle cerebral artery occlusion...
The research was to analyze the number and pattern of microsatellites in Periplaneta americana’s genome, also developed tetranucleotide SSR markers. We thoroughly scrutinized dissected inherent traits that govern allocation microsatellite sequences within profound domain P. software MSDBv2 allowed for utilization 2.67 Gb. There were precisely 1,498,458 flawless sequences, encompassed approximately 1.57%. cumulative length 45,076,707 bp, abundance 16889.577 loci/Mb. Out all repeat variations,...
To present on a prenatally diagnosed case with complex structural rearrangements of chromosome 8.Chromosome karyotyping, chromosomal microarray analysis (CMA) and fluorescence in situ hybridization (FISH) were carried out for fetus increased nuchal thickness.The karyotype the amniotic fluid sample showed extra materials 8p. FISH revealed centromeric signal at terminal 8p absence telomeric signal. CMA partial deletion 8p23.3 [(208049_2256732)×1], duplication 8p23.3p23.2 [(2259519_3016818)×3],...
The study aimed to explore the risk factors of effects patients with vascular mild cognitive impairment (VaMCI) through functional magnetic resonance imaging (fMRI). In this study, 62 were selected from department neurology, admitted Changzhi People's Hospital October 1, 2018 February 2020. Patients VaMCI defined as group according Clinical Dementia Rating (CDR), and subjects normal function control (NC) group. All underwent fMRI identify amplitude low-frequency fluctuation (ALFF) regional...