A5073471166- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Transcranial Magnetic Stimulation Studies
University Hospital Cologne
2021-2024
University of Cologne
2021-2024
The effects of subthalamic stimulation (subthalamic nucleus-deep brain stimulation, STN-DBS) on impulsive and compulsive behaviours (ICB) in Parkinson's disease (PD) are understudied.To investigate clinical predictors STN-DBS ICB.In this prospective, open-label, multicentre study patients with PD undergoing bilateral STN-DBS, we assessed preoperatively at 6-month follow-up postoperatively. Clinical scales included the Questionnaire for Impulsive-Compulsive Disorders PD-Rating Scale...
The satisfaction with life and, in particular, treatment Parkinson's disease (PD) is understudied.To explore a new 7-item rating tool assessing and (SLTS-7) PD.In this cross-sectional, multi-center study, including patients screened for advanced therapies, psychometric characteristics of the SLTS-7 were analyzed. An exploratory factor analysis identified underlying factorial structure SLTS-7.117 included, data quality was excellent (computable 100%), acceptability measures satisfied standard...
The effect of subthalamic stimulation (STN-DBS) on patients’ personal satisfaction with life and their Parkinson’s disease (PD) treatment is understudied, as its correlation quality (QoL). Therefore, we tested the hypothesis that STN-DBS for PD enhances treatment. In a prospective, multicenter study 6-month follow-up involving 121 patients, measured main outcomes using Satisfaction Life Treatment Scale (SLTS-7). Secondary included eight-item Questionnaire (PDQ-8), European QoL (EQ-5D-3L),...