A5017184363- Child Nutrition and Feeding Issues
- Food Allergy and Anaphylaxis Research
- Eosinophilic Esophagitis
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Infant Health and Development
- Dermatology and Skin Diseases
- Immunodeficiency and Autoimmune Disorders
- Respiratory and Cough-Related Research
- Voice and Speech Disorders
- Tracheal and airway disorders
- Contact Dermatitis and Allergies
- Human-Animal Interaction Studies
- Clinical Nutrition and Gastroenterology
- Lymphoma Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
National Center For Child Health and Development
2023-2025
Tokyo Metropolitan Hiroo Hospital
2023-2024
Down syndrome (DS) is a risk factor for severe food protein-induced enterocolitis (FPIES), with DS patients tending to have multiple-food FPIES. This the first case where infant history of chronic FPIES milk and soy could effectively be introduced some untested high-risk foods through hospital-based oral challenges (OFCs). The 20-month-old girl DS, who was diagnosed milk- soy-induced Considering her intensive care unit reactions, we considered that introducing other foods, such as wheat...
The association between pet exposure in infancy, early childhood eczema, and FLG mutations remains unclear. This was a birth cohort study performed Tokyo, Japan. primary outcome current eczema based on questionnaire responses collected repeatedly from to 5 years of age. Generalized estimating equations generalized linear modeling were used evaluate the association. Data 1448 participants for analyses. Household dog ownership during gestation, 18 months age significantly reduced risk eczema....
Background: There is a lack of data regarding the early introduction consumption allergenic food among Asian infants. Methods: We examined infants who had early-onset eczema before 6 months age and received instructions from certified allergists for hen’s eggs, milk, wheat, peanuts, tree nuts. Results: The rates eggs were 100% at 24 months. For peanuts walnuts, rate was moderate 12 (48.5% 30.3%, respectively), but by months, it progressed to 78.8% 81.3%, respectively. In contrast, cashews...
The aim of this study was to evaluate the basic performance and accuracy as a screening test by comparing SiLIS Allergy 45+1 with View 39.
Currently, individual participant data sharing is unavailable because the IRB permission has not yet been obtained under Ethical Guidelines for Medical and Biological Research Involving Human Subjects Personal Information Protection Commission, Japan. The will be available after granted. Any queries can emailed to Primary Investigator Kiwako Yamamoto-Hanada at [email protected].
Inducible laryngeal obstruction (ILO) refers to respiratory disorders caused by airflow limitation in the larynx, including vocal cord dysfunction, and may sometimes be misdiagnosed as bronchial asthma (BA). Here, we report case of an 11-year-old boy diagnosed with BA infancy. He was referred our Allergy Center taking a high dose inhaled corticosteroids (ICS) due frequent coughing from age 10 years persistent following COVID-19 infection at 11. However, patient continued experience attacks...
急性食物蛋白誘発胃腸炎(acute FPIES)の経口食物負荷試験(OFC)における,OFC施行時期,過去の症状の重症度や負荷量と,OFCでの誘発症状の重症度の関係については明らかでない.今回,生後1か月まで混合栄養で症状がなかったが,生後3か月時の普通ミルク再導入により軽症のacute FPIESを疑う症状を呈し,確定診断のために国際コンセンサスガイドラインに準拠した通常負荷量でOFCを施行したところ,意識障害やアシドーシスを伴う重症な症状を呈したacute FPIESの乳児例を経験したため報告する.乳児期,また最終エピソードからOFCまでの期間が短い場合は,ガイドラインに準拠した負荷量でも重症の誘発症状を生じる可能性があり,負荷量設定,緊急時対応の事前準備が,安全なOFC実施に重要である.Acute FPIESに対するOFCの方法はまだ標準化されておらず,今後のエビデンスの蓄積が必要である.