A5100723159- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Antibiotic Use and Resistance
- Hematological disorders and diagnostics
- Acute Myeloid Leukemia Research
- Bacterial Identification and Susceptibility Testing
- Pleural and Pulmonary Diseases
- Cardiac Valve Diseases and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Neutropenia and Cancer Infections
- Medical Imaging and Pathology Studies
- Hemostasis and retained surgical items
- Cardiac Imaging and Diagnostics
- Reconstructive Surgery and Microvascular Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Nosocomial Infections in ICU
- Antibiotic Resistance in Bacteria
Soochow University
2023-2025
First Affiliated Hospital of Soochow University
2023-2025
Sun Yat-sen University
2018-2021
Sun Yat-sen University Cancer Center
2018-2021
State Key Laboratory of Oncology in South China
2018-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2019
Cancer Institute (WIA)
2019
Peking Union Medical College Hospital
2018
State Key Laboratory of Respiratory Disease
2018
Wenzhou Medical University
2018
Purpose The efficacy of neoadjuvant chemoradiotherapy (NCRT) plus surgery for locally advanced esophageal squamous cell carcinoma (ESCC) remains controversial. In this trial, we compared the survival and safety NCRT with alone in patients ESCC. Patients Methods From June 2007 to December 2014, 451 potentially resectable thoracic ESCC, clinically staged as T1-4N1M0/T4N0M0, were randomly allocated (group CRT; n = 224) S; 227). group CRT, received vinorelbine 25 mg/m2 intravenously (IV) on days...
Few studies have exclusively investigated the value of pathological complete response (pCR), in esophageal squamous cell carcinoma (ESCC) patients, although it is a clinically significant parameter to evaluate impact neoadjuvant chemoradiotherapy (nCRT) on treatment outcome after surgery. The aim our study was explore relationship between pCR nCRT and survival among patients with local ESCC.All receiving followed by surgery NEOCRTEC5010-trial (NCT01216527) were included. Non-pCR classified...
Objective: This study retrospectively analyzed the clinical characteristics of patients newly diagnosed with acute myeloid leukemia (AML) who were admitted to hematology intensive care unit (HCU) critical illness. It also examined factors associated illness and early mortality in these patients. Methods: Clinical data collected from 91 AML HCU Department Hematology, First Affiliated Hospital Soochow University, October 2020 2024. Reasons for admission, major therapeutic interventions, risk...
Esophagectomy is a pivotal curative modality for localized esophageal or esophagogastric junction cancer (EC EJC). Postoperative anastomotic leakage (AL) remains problematic. The use of fibrin sealant (FS) may improve the strength anastomosis and reduce incidence AL.To assess efficacy safety applying FS to prevent AL in patients with EC EJC.In this single-arm, phase II trial (Clinicaltrial.gov identifier: NCT03529266), we recruited aged 18-80 years resectable EJC clinically staged as...
Objective: To assess the efficacy and safety of polymyxin B in neutropenic patients with hematologic disorders who had refractory gram-negative bacterial bloodstream infection. Methods: From August 2021 to July 2022, we retrospectively analyzed infection were treated Department Hematology First Affiliated Hospital Soochow University between 2022. The cumulative response rate was then computed. Results: study included 27 infections. Polymyxin therapy effective 22 patients. median time onset...
Background: Surgery is the primary treatment for esophageal or esophagogastric junction cancer (EC EJC), but anastomotic leakage (AL) remains problematic. The use of fibrin sealant (FS) may reduce incidence AL. We aimed to assess efficacy and safety application porcine FS in prevention cervical AL patients with EC EJC. Methods: In this phase 2, single-arm, prospective study, we recruited aged 18-80 years resectable EJC, clinically staged as T1-4aN0-3M0. An open minimally invasive McKeown...