A5042345014- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neuroendocrine Tumor Research Advances
- Occupational exposure and asthma
- Sarcoidosis and Beryllium Toxicity Research
- Neuroblastoma Research and Treatments
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Pulmonary Hypertension Research and Treatments
University of Padua
2021-2025
Background Recent literature has shown the presence of B cells and autoantibodies in idiopathic pulmonary fibrosis (IPF) which would imply tertiary lymphoid structures (TLS, sites where immune response is triggered), yet TLS are not considered features histological characteristics IPF. Aim This study aims to quantify presence, size, degree activation biopsied explanted lungs from patients with early- late-IPF, never treated antifibrotics, relate their activity clinical course, disease...
This report describes the case of a 46-year-old non-smoker housewife. She presented to our attention having diagnosis "difficult asthma" from another center in previous two years. had no allergies and not been exposed an excessive amount noxious stimuli. Her chronic respiratory symptoms (dyspnea on exertion with wheezing) remained uncontrolled despite maximal anti-asthmatic inhaled therapy. An HRCT scan was performed further investigate other pulmonary diseases that mimic asthma. It revealed...
<b>Background:</b> Increasing evidence suggests that an immune dysregulation may be involved in the progression of IPF. The presence lymphoid follicles (LF) (sites where response is triggered) earlyIPF and their evolution with disease, have never been caracterized as part natural history <b>Aim:</b> 1) To investigate LF earlyIPF(EIPF) end-stage late IPF(LIPF) 2) quantify numbers, dimensions state activation from EIPF to LIPF. <b>Methods:</b> immunostained for B-lymphocytes were counted...