A5000738539- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Mechanical Circulatory Support Devices
- IL-33, ST2, and ILC Pathways
- Diabetes Management and Research
- Eosinophilic Esophagitis
- Pneumothorax, Barotrauma, Emphysema
- Chronic Lymphocytic Leukemia Research
- Long-Term Effects of COVID-19
- Lung Cancer Research Studies
- Airway Management and Intubation Techniques
- Pediatric health and respiratory diseases
- Neuroblastoma Research and Treatments
- Lymphoma Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Air Quality and Health Impacts
- COVID-19 Clinical Research Studies
- Neuroendocrine Tumor Research Advances
- Pulmonary Hypertension Research and Treatments
- Lymphatic Disorders and Treatments
- Diabetes Treatment and Management
- Respiratory and Cough-Related Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Ca' Foncello Hospital
2022-2023
University of Padua
1996-2022
Azienda Ospedaliera di Padova
2020
SARS-CoV-2 may lead to a large spectrum of respiratory manifestations, including pulmonary sequelae. We conducted single-center longitudinal study survivors from severe COVID-19 cases who underwent chest CT during hospitalization (CTH). Three months after being discharged, these patients were evaluated by clinical examination, function tests and chest-CT scan (CTFU). Sixty-two enrolled. At follow-up, 27% complained exertional dyspnoea 12% cough. Dyspnoeic had lower forced expiratory flow...
Background: Patients with COVID-19 may experience hypoxemic Acute Respiratory Failure (hARF) requiring O2-therapy by High-Flow Nasal Cannula (HFNO). Although Prone Positioning (PP) improve oxygenation in non-intubated patients, the results on its clinical efficacy are controversial. The present study aims to prospectively investigate whether PP reduce need for endotracheal intubation (ETI) patients receiving HFNO. Methods: All consecutive unselected adult bilateral lung opacities chest X-ray...
Introduction Air pollution is a risk factor for respiratory infections and asthma exacerbations. We previously reported impaired Type-I Type-III interferons (IFN-β/λ) from airway epithelial cells of preschool children with and/or atopy. In this study we analyzed the association between rhinovirus-induced IFN-β/λ expression acute exposure to principal outdoor air pollutants in same cohort. Methods studied 34 (17asthmatics/17non-asthmatics) undergoing fiberoptic bronchoscopy clinical...
This report describes the case of a 46-year-old non-smoker housewife. She presented to our attention having diagnosis "difficult asthma" from another center in previous two years. had no allergies and not been exposed an excessive amount noxious stimuli. Her chronic respiratory symptoms (dyspnea on exertion with wheezing) remained uncontrolled despite maximal anti-asthmatic inhaled therapy. An HRCT scan was performed further investigate other pulmonary diseases that mimic asthma. It revealed...
<b>Background:</b> Asthma in children is usually considered a T2-high (T2H) atopic disease, yet the T2H non-atopic and T2-low (T2L) endotypes, seen adults, have not been well defined children. <b>Aim:</b> To investigate expression of innate lymphoid cells-2 (ILC2), IL-4 IL-5 different endotypes childhood asthma. <b>Methods:</b> In bronchial biopsies 109 (61 with, 48 without asthma) undergoing clinical indicated bronchoscopy, we quantified by immunohistochemistry eosinophils (eos), ILC2,...
Presentiamo il caso di un uomo affetto da dispnea ed ipossiemia persistenti, ma con esame obiettivo, volumi polmonari e radiografia del torace nella norma. Anamnesi patologica remota sostanzialmente muta. Questa presentazione deve far pensare all’ipertensione polmonare idiopatica, una patologia relativamente rara che essere sospettata nei pazienti lamentano sforzo, ipossiemia, dolore toracico oppressivo o tosse persistente, in presenza quadro funzionale radiologico essenzialmente negativo.
<b>Background:</b> Asthma can present in early age and progress through adulthood or de novo adulthood. <b>Aim:</b> to investigate possible differences pathogenetic clinical features of early-onset asthma persisting into late-onset asthma. <b>Method:</b> We conducted a cross-sectional study 250 adult patients (54±16 years-old) recruited at our clinic. defined persistent (EOA) as onset <12 years (LOA) >40 years. Severity was graded by GINA steps (STEP1, 2, 3 controlled; STEP3...
We describe the case of a 56 years-old man with subacute onset symptoms mimicking granulomatosis polyangiitis. He was admitted to our hospital acute respiratory failure requiring oxygen therapy, fever and crusted rhinitis. Despite initial improvement in radiological clinical features steroids his condition worsened rapidly he re department ARDS. antibiotic, antiviral antifungal an endotracheal intubation necessary ultimately patient passed away. Only histological examination on autopsy had...
<b>Background:</b> Age of asthma onset may have significant pathogenetic implications. While early and late phenotypes been well studied, intermediate onset-asthma is not understood. <b>Aim:</b> To investigate the impact comorbidities, smoking history inflammatory on control (GINA) in patients stratified by age onset. <b>Methods:</b> In a cohort 250 patients(54±16 yr) followed at clinic 3 clusters were defined: early-onset asthma(EA)<12 yr; asthma(IA) 12-40 late-onset asthma(LA)>40 yr....