A5014844988- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Protease and Inhibitor Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Sarcoidosis and Beryllium Toxicity Research
- GDF15 and Related Biomarkers
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hair Growth and Disorders
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Global Cancer Incidence and Screening
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac Arrest and Resuscitation
- COVID-19 and healthcare impacts
- Peptidase Inhibition and Analysis
- Inflammasome and immune disorders
- Transplantation: Methods and Outcomes
- Tracheal and airway disorders
- Dermatological and COVID-19 studies
University of Padua
2021-2025
Pulmonary fibrosis (PF), a pathological outcome of chronic and acute interstitial lung diseases associated to compromised wound healing, is key component the "post-acute COVID-19 syndrome" that may severely complicate patients' clinical course. Although inconclusive, available data suggest more than third hospitalized patients develop fibrotic abnormalities after their discharge from hospital. The pathogenesis PF in recovering severe case complex, several hypotheses have been formulated...
Background: Patients suffering from idiopathic pulmonary fibrosis (IPF) may experience acute exacerbation (AE-IPF), which frequently results in respiratory failure (ARF) requiring hospitalization. Objective: This study aims to determine if survival has improved over the last decade patients hospitalized for ARF consequent AE-IPF, view of progress recently made pharmacological and supportive treatment strategies. Methods: was an observational retrospective single-center study. The data 14...
Post-acute COVID-19 is characterized by the persistence of dyspnea, but pathophysiology unclear. We evaluated prevalence dyspnea during follow-up and factors at admission associated with persistence. After five months from discharge, 225 consecutive patients hospitalized for moderate to severe pneumonia were assessed clinically laboratory tests, echocardiography, six-minute walking test (6MWT), pulmonary function tests. Fifty-one reported persistent dyspnea. C-reactive protein (p = 0.025, OR...
Background: A higher risk for COVID-19 infection and severity men compared to women has been described since the beginning of pandemic. The role androgens recently highlighted as they control two key steps coronavirus mediated through transmembrane protease serin 2 (TMPRRS2) angiotensin-converting enzyme (ACE2) receptor in lung tissue. Furthermore, a high incidence androgenic alopecia among males with disease have reported.Objective: This study aims evaluate telogen effluvium (TE) prevalence...
(1) Background: Emerging data regarding patients recovered from COVID-19 are reported in the literature, but cardiac sequelae have not yet been clarified. To quickly detect any involvement at follow-up, aims of research were to identify: elements admission predisposing subclinical myocardial injury follow up; relationship between and multiparametric evaluation follow-up; longitudinal evolution. (2) Methods Results: A total 229 consecutive hospitalised for moderate severe pneumonia initially...
Background: Patients with COVID-19 may experience hypoxemic Acute Respiratory Failure (hARF) requiring O2-therapy by High-Flow Nasal Cannula (HFNO). Although Prone Positioning (PP) improve oxygenation in non-intubated patients, the results on its clinical efficacy are controversial. The present study aims to prospectively investigate whether PP reduce need for endotracheal intubation (ETI) patients receiving HFNO. Methods: All consecutive unselected adult bilateral lung opacities chest X-ray...
(1) Background: Because of a complicated intraoperative course and/or poor recovery graft function, approximately 15% lung transplant (LT) recipients require prolonged mechanical ventilation (PMV) and receive tracheostomy. This prospective study aimed to assess the effect High-Flow Tracheal Oxygen (HFTO) on tracheostomy tube removal in LT receiving PMV postoperatively. (2) Methods: The clinical 14 HFTO was prospectively evaluated compared that 13 comparable controls conventional oxygen...
A previous analysis carried out in Northeastern Italy reported a 14% increase the number of COPD-related deaths 2020 compared to 2018-2019 average. The study aimed assess impact all pandemic waves on mortality by means time series analyses causes death data yearly and monthly age-standardized rates residents aged ≥40 ys with any mention COPD were extracted from Venetian region registry, January 1, 2008, March 31, 2022. Using age standardized rates, generalized estimating equation (GEE)...
<b>Background:</b> Cell entry of coronaviruses depends on the viral spike S protein priming by serine protease TMPRSS2. A protease-antiprotease imbalance, in particular deficiency Alpha1-Antitrypsin (AAT), could play a central role virulence SARS-CoV-2 (Vianello and Braccioni F. Arch Bronconeumol. 2020;56:609-10). <b>Aims objecives:</b> To investigate prevalence AAT (AATD) among adult patients with ARDS consequent to infection. <b>Methods:</b> Subjects who recovered from (group A)...