A5027371207- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Transplantation: Methods and Outcomes
- Long-Term Effects of COVID-19
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Spine and Intervertebral Disc Pathology
- Meta-analysis and systematic reviews
- COVID-19 diagnosis using AI
- Organ Transplantation Techniques and Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Chronic Obstructive Pulmonary Disease (COPD) Research
University of Padua
2015-2025
Azienda Ospedaliera di Padova
2016-2024
March of Dimes
2013-2023
VA Palo Alto Health Care System
2021
Stanford University
2021
Santa Maria Nuova Hospital
2018
University of Virginia Health System
2015
Barro Colorado Island
2015
University of Virginia
2011-2013
American Heart Association
2013
In late December 2019 an outbreak of a novel coronavirus (SARS-CoV-2) causing severe pneumonia (COVID-19) was reported in Wuhan, Hubei Province, China. A common finding most COVID-19 patients is high D-dimer levels which are associated with worse prognosis. We aimed to evaluate coagulation abnormalities via traditional tests and whole blood thromboelastometry profiles group 22 (mean age 67 ± 8 years, M:F 20:2) consecutive admitted the Intensive Care Unit Padova University Hospital for acute...
Background Clinically used general anesthetics, alone or in combination, are damaging to the developing mammalian brain. In addition causing widespread apoptotic neurodegeneration vulnerable brain regions, exposure anesthesia at peak of synaptogenesis causes learning and memory deficiencies later life. vivo rodent studies have suggested that activation intrinsic (mitochondria-dependent) pathway is earliest warning sign neuronal damage, suggesting a disturbance mitochondrial integrity...
Abstract Background: General anesthetics induce apoptotic neurodegeneration in the developing mammalian brain. anesthesia (GA) also causes significant disturbances mitochondrial morphogenesis during intense synaptogenesis. Mitochondria are dynamic organelles that undergo remodeling via fusion and fission. The fine balance between these two opposing processes determines morphometric properties, allowing for their regeneration enabling normal functioning. As mitochondria exquisitely sensitive...
The American Society of Anesthesiologists physical status (ASA-PS) is a grading system adopted worldwide by anesthesiologists to classify the overall health patients. Its importance demonstrated not only its routinely use in clinical practice, but also deployment other healthcare-related environments. However, weak/moderate inter-observer agreement for ASA-PS has been previously shown and, although definitions and examples each class were provided ASA, doubts remain on individual factors...
Abstract Objectives Thrombin generation (TG) with and without thrombomodulin (TM) was evaluated in COVID-19 patients different disease severity thromboprophylaxis regimen, order to understand the prothrombotic profile. Methods We enrolled consecutive confirmed diagnosis of admitted Medical Departments (MD) or Intensive Care Units (ICU), 54 healthy controls. Results Eighty-nine were included (mean age 60.4±16.1 years, 68.5% male); 33.7% ICU. Twenty-four (26.9%) before administration; 45...
Investigating the health-related quality of life (HRQoL) after intensive care unit (ICU) discharge is necessary to identify possible modifiable risk factors. The primary aim this study was investigate HRQoL in COVID-19 critically ill patients one year ICU discharge.
Abstract Purpose Erector spinae plane (ESP) block is an interfascial blockade used in different clinical scenarios. This study investigated the ventral extent of dye diffusion ESP block. Methods The ultrasound-guided was bilaterally performed with injection at T5 vertebral level (21-Gauge, 50 mm needle), using diluted black tissue marking (20 mL; 1:4 ratio standard saline solution) instead local anesthetic on two fresh-frozen corpses within body donation program University Padova....
Despite thromboprophylaxis, patients with coronavirus disease 2019 (COVID-19) exhibit hypercoagulability and higher venous thromboembolic risk, although its real incidence is still unknown. The aim of this study was to evaluate the thromboembolism (VTE) in COVID-19 admitted both intensive care units (ICUs) medical wards (MWs). Consecutive for MW ICU at Padua University Hospital, all receiving underwent systematic ultrasonography internal jugular, upper lower limbs veins every 7 days (± 1...
Introduction Erector spinae plane (ESP) block is an emerging interfascial with a wide range of indications for perioperative analgesia and chronic pain treatment. Recent studies have focused their attention on mechanisms action ESP block. However, the pharmacokinetics drugs injected in is, as now, uninvestigated. The aim this brief report to investigate lidocaine series 10 patients. Methods We are reporting case patients undergoing bilateral multilevel lumbar spine surgery. was performed 3.5...
The risk of barotrauma associated with different types ventilatory support is unclear in COVID-19 patients. primary aim this study was to evaluate the effect respiratory strategies on occurrence; we also sought determine frequency and clinical characteristics patients who experienced complication.
Abstract The efficacy of non-invasive ventilation (NIV) in acute respiratory failure secondary to SARS-CoV-2 infection remains controversial. Current literature mainly examined efficacy, safety and potential predictors NIV provided out the intensive care unit (ICU). On contrary, outcomes ICU patients, intubated after failure, remain be explored. aims present study are: (1) investigating in-hospital mortality coronavirus disease 2019 (COVID-19) patients receiving endotracheal intubation (2)...
An increasing number of reports have described the COVID-19-associated pulmonary aspergillosis (CAPA) as being a further contributing factor to mortality. Based on recent consensus statement supported by international medical mycology societies, it has been proposed define CAPA possible, probable, or proven basis sample validity and thus diagnostic certainty. Considering current challenges associated with diagnoses, there is pressing need study epidemiology CAPA.We report incidence...
Retracted articles represent research withdrawn from the existing body of literature after publication. Research may be retracted for several reasons ranging honest errors to intentional misconduct. They should not used as reliable sources, and it is unclear why they are cited occasionally by other articles. This study hypothesized that mechanisms contribute citing aimed analyze characteristics in anesthesiology critical care.Using Retraction Watch database, we retrieved on intensive care...