- Cardiac, Anesthesia and Surgical Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Cardiac and Coronary Surgery Techniques
- Anesthesia and Sedative Agents
- Traumatic Brain Injury Research
- Anesthesia and Neurotoxicity Research
- Organ Transplantation Techniques and Outcomes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Long-Term Effects of COVID-19
- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- Aortic Disease and Treatment Approaches
- COVID-19 Clinical Research Studies
- Optical Imaging and Spectroscopy Techniques
- Transplantation: Methods and Outcomes
- Spinal Fractures and Fixation Techniques
- Cardiac Ischemia and Reperfusion
- Epilepsy research and treatment
- Organ Donation and Transplantation
- Cardiac Valve Diseases and Treatments
- Cardiovascular and Diving-Related Complications
- Vestibular and auditory disorders
- Pericarditis and Cardiac Tamponade
Ca' Foncello Hospital
2010-2025
Azienda Ospedaliera Universitaria Integrata Verona
2017-2024
University of Verona
2017-2024
AULSS 2 Marca Trevigiana
2011-2023
University of Campania "Luigi Vanvitelli"
2020-2021
University of Padua
2008-2021
European Society of Anaesthesiology
2014
Azienda Ospedaliero-Universitaria Careggi
2006
Ospedale di Santa Maria dei Battuti
1998
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
1991
A 45 year old male obese patient with a previous history of repaired congenital heart disease developed worsening failure making transplantation listing mandatory. Unfortunately, due to his anthropometric measures, the search for suitable brain-dead donor was unsuccessful. For this reason, he accepted be enrolled in controlled donation after circulatory death (cDCD) program. According Italian Law regulating declaration cardiac arrest (no-touch period 20 minutes-one longest world), we faced...
Abstract The efficacy of non-invasive ventilation (NIV) in acute respiratory failure secondary to SARS-CoV-2 infection remains controversial. Current literature mainly examined efficacy, safety and potential predictors NIV provided out the intensive care unit (ICU). On contrary, outcomes ICU patients, intubated after failure, remain be explored. aims present study are: (1) investigating in-hospital mortality coronavirus disease 2019 (COVID-19) patients receiving endotracheal intubation (2)...
Extracorporeal membrane oxygenation (ECMO) supplies systemic blood perfusion and gas exchange in patients with cardiopulmonary failure. The current literature lacks of papers reporting the possible risks microembolism among complications this treatment.In study we present our preliminary experience on brain flow velocity emboli detection through transcranial Doppler monitoring during ECMO.Six suffering heart failure, four after cardiac surgery two resuscitation were treated ECMO submitted to...
Lung protective strategies using low tidal volumes and moderate positive end expiratory pressures (PEEP) are considered best practice in critical care, but interventional trials have never been conducted acutely brain-injured patients due to concerns about carbon dioxide control effect of PEEP on cerebral hemodynamic.
Donation after circulatory death (DCD) donation is becoming more and popular worldwide. However, in this setting of donation, heart graft suffers from the ischemic injury related with cardiac arrest. In Italy, declaration parameters requires registration electrocardiograph for twenty minutes resulting a very prolonged grafts' warm ischemia time. The aim study to present Italian preliminary experience on transplantation (HTx) controlled DCD (cDCD) donors. Despite long period time (WIT)...
Background: Midazolam is widely used in clinical anesthesia, but its effects on the Bispectral Index (BIS) and propofol concentration at effector site (CeP) are underexplored. This study investigates pharmacodynamic interaction between midazolam total intravenous anesthesia (TIVA) with target-controlled infusion (TCI), focusing Schnider Eleveld models. Methods: prospective included breast surgery patients receiving TIVA-TCI. BIS CeP were assessed loss of responsiveness (LoR), during...
This extension study investigated the association between preoperative cerebral blood flow (CBF) velocity and postoperative cognitive decline (POCD) at a three-month follow-up in patients who underwent cardiac surgery. Continuous transcranial Doppler ultrasound on both middle arteries (MCAs) was used preoperatively 31 right-handed surgery rest. Each patient performed neuropsychological evaluation to assess performance before surgery, discharge follow-up. Patients with POCD had marginally...
Abstract Background Pathophysiological features of coronavirus disease 2019-associated acute respiratory distress syndrome (COVID-19 ARDS) were indicated to be somewhat different from those described in nonCOVID-19 ARDS, because relatively preserved compliance the system despite marked hypoxemia. We aim ascertaining whether static (Crs), driving pressure (DP), and tidal volume normalized for ideal body weight (VT/kg IBW) at 1st day controlled mechanical ventilation are associated with...
<h3>BACKGROUND AND PURPOSE:</h3> Early brain injury is a major determinant of clinical outcome in poor-grade (World Federation Neurosurgical Societies [WFNS] IV–V) aneurysmal SAH and radiologically defined by global cerebral edema. Little known, though, about the effect intracranial hemorrhage volume on early development outcome. <h3>MATERIALS METHODS:</h3> Data from multicentric prospective Poor-Grade Aneurysmal Subarachnoid Hemorrhage (POGASH) Registry consecutive patients with admitted...
Postoperative cognitive decline (POCD) is a frequent complication after cardiac surgery. Although intraoperative events are risk factors for POCD, the role played by preoperative hypoperfusion in has not yet been investigated. It also unknown whether impact of left or right middle cerebral arteries (MCAs) can differentially account POCD. The main aims this study were to investigate was associated with early POCD and lateralized would affect patients surgery.Bilateral MCA continuous...
Background: Adverse neurological events during extracorporeal membrane oxygenation (ECMO) are common and may be associated with devastating consequences. Close monitoring, early identification prompt intervention can mitigate late morbidity. Neuromonitoring neurocognitive/neurodevelopmental follow-up critically important to optimize outcomes in both adults children. Objective: To assess current practice of neuromonitoring ECMO after across Europe inform the development guidelines. Methods:...
BACKGROUND: Scarce data are available regarding rebleeding predictors in poor-grade aneurysmal subarachnoid hemorrhage (aSAH). OBJECTIVES: To investigate and clinical impact of a national multicentric aSAH. METHODS: Retrospective analysis prospectively collected from the Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group (POGASH) registry consecutive patients treated January 1, 2015, to June 30th, 2021. Grading was defined as pretreatment World Federation Neurological Surgeons grading...
Early prediction of a good outcome in comatose patients after cardiac arrest still remains an unsolved problem. The main aim the present study was to examine accuracy middle-latency SSEP triggered by painful electrical stimulation on median nerves predict favorable outcome.No- and low-flow times, pupillary reflex, Glasgow motor score biochemical data were evaluated at ICU admission. following considered within 72 h arrest: highest creatinine value, hyperthermia occurrence, EEG, low- (10 mA)...