A5026035028- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Viral Infections and Immunology Research
- Global Health Care Issues
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Virus-based gene therapy research
- Herpesvirus Infections and Treatments
- Thermoregulation and physiological responses
- Per- and polyfluoroalkyl substances research
- Immunodeficiency and Autoimmune Disorders
- Thermal Regulation in Medicine
- Parvovirus B19 Infection Studies
- Viral gastroenteritis research and epidemiology
- Air Quality Monitoring and Forecasting
- Toxin Mechanisms and Immunotoxins
- Ginkgo biloba and Cashew Applications
- Eosinophilic Disorders and Syndromes
- COVID-19 epidemiological studies
- Noise Effects and Management
- Cytomegalovirus and herpesvirus research
- Celiac Disease Research and Management
- Bird parasitology and diseases
- Connective Tissue Growth Factor Research
- SARS-CoV-2 and COVID-19 Research
University of Padua
2007-2024
Barcelona Institute for Global Health
2024
Public Health Department
2021
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2019
University of Turin
2019
Azienda USL di Bologna
1992
<h3>Background</h3> Motor Neurone Disease (MND) is a life-shortening condition with no cure. Consequently, hospice and palliative care are recommended from diagnosis. Family carers provide vital support for people MND but caregiving can be very physically mentally demanding. It therefore crucial to ensure healthcare practitioners (HCPs) timely fitting their individual needs. Currently there UK interventions this. <h3>Aim</h3> To adapt an existing Carer Support Needs Assessment Tool (CSNAT)...
Objective: Overall mortality is a relevant indicator of the population burden during an epidemic. It informs on both undiagnosed cases and effects health system disruption. Methods: We aimed at evaluating extent total death excess COVID-19 epidemic in Italy. Data from 4433 municipalities providing reports until April 15th, 2020 were included for 34.5 million residents all Italian regions. analyzed by region, sex age, compared to expected 2015–2019. Results: In genders, overall was stable...
Abstract Ginkgolic acids (GA) are alkylphenol constituents of the leaves and fruits Ginkgo biloba . GA has shown pleiotropic effects in vitro , including: antitumor through inhibition lipogenesis; decreased expression invasion associated proteins AMPK activation; potential rescue amyloid-β (Aβ) induced synaptic impairment. was also reported to have activity against Escherichia coli Staphylococcus aureus Several mechanisms for this been suggested SUMOylation inhibition; blocking formation...
Abstract Background Guidelines about febrile neutropenia in paediatric patients are not homogeneous; the best empiric treatment of this condition should be driven by local epidemiology. The Weighted-Incidence Syndromic Combination Antibiogram (WISCA) addresses need for disease-specific susceptibility evidence that could guide antibiotic prescriptions based on outcome estimates regimens obtained as a weighted average pathogen susceptibilities. This study developed WISCA model to inform...
The year of 2024 was the warmest on record, both globally and in Europe, first to exceed 1.5&#176;C global mean temperature above preindustrial level. Successive record-breaking temperatures recent years emphasized urgent need develop implement a new generation impact-based early-warning systems (EWS), using epidemiological models transform weather forecasts into health predictions (see https://forecaster.health/).Here we combined newly created daily continental mortality database...
Herpes simplex virus type 1 (HSV-1) causes a lifelong latent infection with an estimated global prevalence of 66%. Primary and recurrent HSV infections are characterized by tingling sensation, followed eruption vesicles, which can cause painful erosions. Commonly used antiviral drugs against nucleoside analogues including acyclovir (ACV), famciclovir, valacyclovir. Although these reduce morbidity mortality in immunocompetent individuals, ACV-resistant strains (ACVR-HSV) have been isolated...
Canine visceral leishmaniasis frequently causes renal damage that leads to chronic kidney disease. Fifteen dogs seropositive for Leishmania were selected and biopsied before (T0) 60 days later after (T1) treatment with a specific anti- pharmacological agent. Various parameters evaluating the glomerular tubulointerstitial damage. At T0, mesangioproliferative membranoproliferative glomerulonephritis observed in 6 dogs, glomerulosclerosis 5, end-stage 3; tissue from 1 dog was within normal...
Background Finding of intracardiac lead masses in patients with cardiac implantable electronic devices remains controversial, as such have been observed cases exclusively local infections whereas they not recognized positive cultures intravascular fragments. In this study, we aim to describe the prevalence true asymptomatic devices, identify their predictive factors and define prognostic impact at long-term follow-up. Methods Seventy-eight consecutive admitted over a 6-month period for...
Several epidemiological studies found an association between acute exposure to fine particulate matter of less than 2.5 μm and 10 in aerodynamic diameter (PM2.5 PM10) cardiovascular diseases, ventricular fibrillation incidence mortality. The effects pollution on atrial (AF) beyond the first several hours remain controversial. A total 145 patients with implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy defibrillators (ICD-CRT), or pacemakers were enrolled this...
X-linked hereditary nephropathy (XLHN) in Navasota dogs is a spontaneously occurring disease caused by mutation resulting defective production of type IV collagen and juvenile-onset renal failure. The study was aimed at examining the evolution damage expression selected molecules potentially involved pathogenesis XLHN. Clinical data samples were obtained 10 XLHN male 5 controls 4 (T0), 6 (T1), 9 (T2) months age. Glomerular tubulointerstitial lesions scored light microscopy, 21 investigated...
Rationale: Outdoor air pollution contributes to asthma development and exacerbations, yet its effects on airway pathology have not been defined in children. Objectives: To explore the possible link between pathology, we retrospectively examined relationship environmental pollutants pathological changes bronchial biopsy specimens from children undergoing a clinically indicated bronchoscopy. Methods: Structural inflammatory (basement membrane [BM] thickness, epithelial loss, eosinophils,...
Background the COVID-19 epidemic severely affected Italy among European countries causing a considerable number of deaths across country, especially in Northern Italy, leading also to serious problems Italian healthcare system, particular overcrowding Intensive Care Units (ICU). In literature, debate on overall mortality during epidemic, directly and indirectly, associated with disease, is still open. Objectives describe time trend pandemic accounting for age, gender, geographical areas....
Introduction Air pollution is a risk factor for respiratory infections and asthma exacerbations. We previously reported impaired Type-I Type-III interferons (IFN-β/λ) from airway epithelial cells of preschool children with and/or atopy. In this study we analyzed the association between rhinovirus-induced IFN-β/λ expression acute exposure to principal outdoor air pollutants in same cohort. Methods studied 34 (17asthmatics/17non-asthmatics) undergoing fiberoptic bronchoscopy clinical...
Abstract Background Italy has been the first European country to be affected by COVID-19 epidemic which started out at end of February. In this report, we focus our attention on Veneto Region, in North-East Italy, is one areas that were rapid spread SARS-CoV-2. We aim evaluate trend all-cause mortality and give a description characteristics studied population. Methods Data used analyses released majority municipalities cover 93% total population living Region. evaluated overall from Jan.01...
Abstract Air pollution has been linked to an increased risk of several respiratory diseases in children, especially tract infections. The present study aims evaluate the association between pediatric emergency department (PED) presentations for bronchiolitis and air pollution. PED due children aged less than 1 year were retrospectively collected from 2007 2018 Padova, Italy, together with daily environmental data. A conditional logistic regression based on a time‐stratified case‐crossover...