A5089483953- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Advanced Radiotherapy Techniques
- Neuroendocrine Tumor Research Advances
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Inflammatory mediators and NSAID effects
- Brain Metastases and Treatment
- Phagocytosis and Immune Regulation
- Bioactive Compounds and Antitumor Agents
- Cytokine Signaling Pathways and Interactions
- Cancer, Lipids, and Metabolism
- Air Quality Monitoring and Forecasting
- Air Quality and Health Impacts
- Lung Cancer Treatments and Mutations
- Natural product bioactivities and synthesis
- Inflammatory Biomarkers in Disease Prognosis
- Angiogenesis and VEGF in Cancer
- Protein Tyrosine Phosphatases
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Ferroptosis and cancer prognosis
- Synthesis and biological activity
- MRI in cancer diagnosis
Chongqing University
2020-2023
Chongqing Cancer Hospital
2020-2023
Civil Aviation Flight University of China
2023
University of California, San Diego
2020-2022
Moores Cancer Center
2022
Lanzhou University
2019
First Hospital of Lanzhou University
2019
Chinese PLA General Hospital
2013-2014
Nankai University
2014
Background: This study aimed to explore the prognostic value of angiogenesis-related genes (ARGs) and their association with immune cell infiltration (ICI) in breast cancer (BC). Methods: Transcriptome data BC were obtained from TCGA GEO databases. Differentially expressed ARGs identified by limma package. The identification key construction risk score model performed univariate multivariate Cox regression algorithms. was assessed ROC curves nomogram. GO, KEGG pathway, GSEA used investigate...
Advanced pancreatic cancer patients have poor prognosis and scarcely respond to conventional therapies. Clinical trials support the use of molecular-targeted therapy against epidermal growth factor receptor (EGFR) signaling. The objective current study was evaluate contribution a monoclonal antibody EGFR, nimotuzumab, standard gemcitabine therapy. Patients with unresectable locally advanced or metastatic adenocarcinoma were assigned receive plus nimotuzumab. primary end point overall...
Abstract Background The leaves of the plant Ilex latifolia Thunb. can be made into Kuding tea, which is a drink rich in polyphenols. This study aimed to observe effect polyphenols (ILTPs) on human lung cancer cell line A549 (A549 cells) by regulating phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway. Methods In vitro cultured cells were treated with ILTPs; proliferation and BEAS-2B normal epithelial (Beas-2B was observed using...
Background and Aims: SH2 domain–containing protein tyrosine phosphatase 2 (Shp2) is the first identified pro‐oncogenic that acts downstream of receptor kinases (RTKs) to promote Ras–extracellular signal–regulated kinase signaling. However, this was also shown be antitumorigenic in HCC. This study aimed at deciphering paradoxical Shp2 functions mechanisms hepatocarcinogenesis exploring its value as a pharmaceutical target HCC therapy. Approaches Results: We took both genetic approaches...
Immunotherapy may be an effective and potentially less toxic treatment for cancer in addition to the traditional therapies. The current study presents a case of advanced pancreatic that was treated with cell‑based immunotherapy using expanded activated allogeneic lymphocytes (EAAL*) vitro cluster differentiation (CD)3(+) CD8(+) cytotoxic T lymphocytes, CD3(‑) CD56(+) natural killer cells as major effector cells, together chemotherapy targeted agents. A 46‑year‑old female diagnosed at Chinese...
Purpose Brain metastases (BMs) are common in Small Cell Lung Cancer (SCLC), but the prognosis is very poor. Currently, there no standard of care on what constitutes optimal treatment, and consensus regarding maintenance therapy SCLC. Case description We report case a 55-year-old man with advanced After initial diagnosis, he received routine chemotherapy chest radiotherapy developed brain 2 lesions seven months later. used an effective combination consisting antiangiogenic inhibitor,...
Objective: To investigate the efficacy and safety of pegaspargase, gemcitabine, oxaliplatin(P-Gemox) chemotherapy combined with radiotherapy in treatment newly diagnosed, stage IE to IIE Extranodal nasal type natural killer/T-cell lymphoma(ENKTL) patients.Method: P-Gemox was used analyze its clinical value factors affecting prognosis 43 diagnosed ENKTL patients. In addition, toxicity related assessed. Result: The complete remission rate 86.05% patients,the partial 6.98%, total effective...
The main visibility forecast factors were identified with the support of data from routine meteorological observations Mianyang Airport and Environmental Monitoring Station 2015 to 2018, a grading model was established tested by dint multiple linear regression KNN algorithm based on big mining technology, variation characteristics in winter at studied. results showed that (1) addition having significant positive correlation wind speed, has negative relative humidity, dew point temperature,...