A. Mamiya

ORCID: 0009-0002-8813-0784
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About
Contact & Profiles
Research Areas
  • RNA Interference and Gene Delivery
  • Cell Adhesion Molecules Research
  • DNA Repair Mechanisms
  • Virus-based gene therapy research
  • Cancer-related molecular mechanisms research
  • Cancer Research and Treatments
  • interferon and immune responses
  • RNA modifications and cancer

Nagoya University
2023

Nihon University
2019

Oncogene-induced DNA replication stress (RS) and consequent pathogenic R-loop formation are known to impede S phase progression. Nonetheless, cancer cells continuously proliferate under such high-stressed conditions through incompletely understood mechanisms. Here, we report taurine upregulated gene 1 (TUG1) long noncoding RNA (lncRNA), which is highly expressed in many types of cancers, as an important regulator intrinsic cells. Under RS conditions, TUG1 rapidly via activation the ATR-CHK1...

10.1038/s41467-023-40243-8 article EN cc-by Nature Communications 2023-08-22
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