Denise Günther

ORCID: 0009-0003-0206-7188
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About
Contact & Profiles
Research Areas
  • Laser Material Processing Techniques
  • Surface Modification and Superhydrophobicity
  • Nanofabrication and Lithography Techniques
  • Advanced Surface Polishing Techniques
  • RNA Research and Splicing
  • Molecular Biology Techniques and Applications
  • Bone Tissue Engineering Materials
  • Tribology and Lubrication Engineering
  • Advanced Semiconductor Detectors and Materials
  • Bone Metabolism and Diseases
  • Semiconductor Quantum Structures and Devices
  • Adhesion, Friction, and Surface Interactions
  • Biochemical and Structural Characterization
  • Technology Use by Older Adults
  • Near-Field Optical Microscopy
  • Osteoarthritis Treatment and Mechanisms
  • Advanced Battery Technologies Research
  • Single-cell and spatial transcriptomics
  • Bacterial biofilms and quorum sensing
  • Microfluidic and Bio-sensing Technologies
  • Advancements in Semiconductor Devices and Circuit Design
  • Advanced Optical Sensing Technologies
  • Fuel Cells and Related Materials
  • 3D Printing in Biomedical Research
  • Pickering emulsions and particle stabilization

Institute for Biomedical Engineering
2024-2025

ETH Zurich
2024-2025

Fraunhofer Institute for Material and Beam Technology
2015-2018

TU Dresden
2015-2018

University of Technology
2016

Forschungszentrum Jülich
2016

ZeptoMetrix (United States)
2006

The changes in structure periods the microscale strongly affect initial bacterial adhesion.

10.1039/c6bm00078a article EN Biomaterials Science 2016-01-01

Starting from a simple concept, transferring the shape of an interference pattern directly to surface material, method Direct Laser Interference Patterning (DLIP) has been continuously developed in last 20 years. From lamp-pumped high power diode-pumped lasers, DLIP permits today for achievement impressive processing speeds even close 1 m<sup>2</sup>/min. The objective: improve performance surfaces by use periodically ordered micro- and nanostructures. This study describes years evolution...

10.1117/12.2252595 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2017-02-17

Direct laser interference patterning (DLIP) is used to produce periodic line-like patterns on titanium surfaces. An Nd:YAG operating at 532 nm wavelength with a pulse duration of 8 ns for the process. The generated spatial periods 5, 10, and 20 µm are produced energy densities between 0.44 2.6 J cm-2 single pulse. With variation density, different shapes arising topography observed due development solidification front molten material maxima positions. Characterization surface chemistry shows...

10.1002/adhm.201600858 article EN Advanced Healthcare Materials 2016-12-08

In recent decades, the field of bone mechanobiology has sought experimental techniques to unravel molecular mechanisms governing phenomenon mechanically regulated fracture healing. Each cell within a site resides different local microenvironments characterized by levels mechanical strain; thus, preserving spatial location each is critical in relating cellular responses stimuli. Our transcriptomics–based “mechanomics” platform facilitates spatially resolved analysis profiles cells with...

10.1126/sciadv.adp8496 article EN cc-by-nc Science Advances 2025-01-01

Here, we present a protocol for using spatial transcriptomics in bone and multi-tissue musculoskeletal formalin-fixed paraffin-embedded (FFPE) samples from mice. We describe steps tissue harvesting, sample preparation, paraffin embedding, FFPE selection. detail procedures sectioning placement on slides prior to imaging, decrosslinking, library final analyses of the sequencing data. The complete takes ca. 18 days mouse femora with adjacent muscle; this time, >50% is required mineralized...

10.1016/j.xpro.2024.102986 article EN cc-by STAR Protocols 2024-03-29

We discuss a new simple InGaAs-InAlAs avalanche photodiode (APD) with planar buried multiplication region. Some of the advantages compared to standard APDs are as follows: 1) The thickness and charge control regions accurately controlled by molecular beam epitaxy growth in contrast diffusion process; 2) InAlAs is material (avalanching faster electrons) instead InP slower holes); 3) gain has lower noise figure than that for InP; 4) guard ring not required; 5) fabrication p-i-n detector; 6)...

10.1109/lpt.2006.881684 article EN IEEE Photonics Technology Letters 2006-08-29

Abstract In recent decades, the field of bone mechanobiology has sought experimental techniques to unravel molecular mechanisms governing phenomenon mechanically-regulated fracture healing. Each cell within a site resides different local micro-environments characterized by levels mechanical strain - thus, preserving spatial location each is critical in relating cellular responses stimuli. Our transcriptomics based “mechanomics” platform facilitates spatially-resolved analysis profiles cells...

10.1101/2024.04.18.590091 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-04-22

Direct laser interference patterning (DLIP) is used to create periodic crater‐ and pillar‐like patterns on titanium surfaces. A Nd:YAG operating at 532 nm wavelength with a pulse duration of 8 ns the ability control polarization each individual beam for process. The generated spatial periods 5 10 μm are produced energy densities between 0.3 5.1 J cm −2 single pulse. By varying interfering density, various forms occurring topography observed due different shape intensity pattern...

10.1002/adem.201800160 article EN Advanced Engineering Materials 2018-04-23

Smart surfaces are a source of innovation in the 21st Century. Potential applications can be found wide range fields where improved optical, mechanical or biological properties enhance functions products. In last years, method called Direct Laser Interference Patterning (DLIP) has demonstrated to capable fabricating periodic surface patterns even with resolution at nanometer and sub-micrometer scales. This article describes recent advances DLIP process 2D 3D parts. Firstly, possibility...

10.1117/12.2214948 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2016-03-14

Hierarchical microstructures offer improved surface functionalities or a combination of properties compared to single‐scale patterns, e.g., low reflectivity and hydrophobicity. The fabrication three‐level length‐scales on polyethylene terephthalate (PET) substrates is demonstrated using UV nanosecond‐pulsed direct laser interference patterning. 1st level created by an array with 10 µm spatial period. 2nd results from the within holographic pixel (1–2 periods), while 3rd related distance (35...

10.1002/adem.201600201 article EN Advanced Engineering Materials 2016-07-19

Springtails are hexapods, which have a complex skin surface composed of periodically arranged mushroom‐like features. This topography offers functionalities like non‐wetting and preventing bacterial settlement. study demonstrates novel way replicating the morphology springtail using interference lithography. The micro patterns produced with an undercut contour in multilayer resist system on Si‐wafers consisting lower lift‐off upper photo‐sensitive resist. After irradiation, several...

10.1002/adem.201600855 article EN Advanced Engineering Materials 2017-02-21

We discuss a new simple InGaAs/InAlAs avalanche photodiode (APD) with planar buried multiplication region. Some of the advantages compared to standard APDs are: 1. The thickness and charge control regions are accurately controlled by molecular beam epitaxy (MBE) growth in contrast diffusion process; 2. InAlAs is material (avalanching faster electrons) instead InP slower holes); 3. gain has lower noise figure than that for InP; 4. A guard ring not required; 5. Fabrication as p-i-n detector;...

10.1117/12.688353 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2006-09-22
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