- Economic and Financial Impacts of Cancer
- Glioma Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Inhalation and Respiratory Drug Delivery
- Patient-Provider Communication in Healthcare
- Palliative Care and End-of-Life Issues
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Spine and Intervertebral Disc Pathology
- Health and Medical Research Impacts
- Brain Metastases and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetic factors in colorectal cancer
- Soft tissue tumor case studies
- COVID-19 and healthcare impacts
- Lung Cancer Treatments and Mutations
- Respiratory viral infections research
- Healthcare Systems and Reforms
- Cancer Immunotherapy and Biomarkers
- HER2/EGFR in Cancer Research
- Spinal Dysraphism and Malformations
- Diabetes Management and Education
University of Cambridge
2021-2025
Brigham and Women's Hospital
2022-2024
Cambridge School
2024
National University Heart Centre Singapore
2021
National University of Singapore
2021
SingHealth Polyclinics
2021
Sri Ramachandra Institute of Higher Education and Research
2018
CDK4/6 inhibitors are oral agents inhibiting key molecules of the cell cycle regulation.In patients with endocrine receptor positive (ER+), human epidermal growth factor 2 negative (HER2-) breast cancer, combination therapy is an effective treatment in metastatic setting.Now, two studies adjuvant setting -MonarchE (2 years abemaciclib) and NATALEE (3 ribociclib)report invasive disease-free survival.Here, we re-evaluate these seminal trials.First, excess drop-out or loss-to-follow up occurred...
Background: Although the Patient Protection and Affordable Care Act (ACA) has been associated with increased Medicaid coverage among prostate cancer patients, association between expansion risk group at diagnosis, time to treatment initiation (TTI), refusal of locoregional (LT) patients requires further exploration. Methods: Using National Cancer Database, we performed a retrospective cohort analysis all aged 40 64 years diagnosed localized from 2011 2016. Difference-in-difference (DID) was...
619 Background: The global burden of genitourinary (GU) cancers has been increasing due to aging populations and advancements in technology. However, little is known about the GU specific Southeast Asia (SEA), a diverse region over 690 million people. This study presents most updated trends incidence mortality bladder, kidney, prostate, testicle across SEA from 1990 2021. Methods: Data were extracted Global Burden Disease (GBD) 2021 database analyze incidence, deaths, age-standardized rates...
Global neurosurgery has witnessed transformative developments in advocacy and policy aimed at overcoming the barriers that hinder equitable access to neurosurgical care. This paper reveals stark disparities faced by low- middle-income countries (LMICs) with an annual burden of 5 million affected individuals. Despite these challenges, emergence global stands as a beacon hope, aspiring deliver timely, safe, affordable Advocacy play pivotal roles this endeavour, exemplified initiatives, like...
OBJECTIVE This study aimed to rigorously assess the accuracy of mixed-reality neuronavigation (MRN) in comparison with magnetic (MN) through a comprehensive phantom-based experiment. It introduces novel dimension by examining influence blue-green light (BGL) on MRN accuracy, previously unexplored avenue this domain. METHODS Twenty-nine phantoms, each meticulously marked 5–6 fiducials, underwent CT scans as part navigation protocol. A 3D model was then superimposed onto 3D-printed plaster...
Hydrocephalus is a significant complication arising from tuberculous meningitis (TBM). While ventriculoperitoneal shunt (VPS) remains the primary surgical approach for TBM-related hydrocephalus, there rising trend in use of endoscopic third ventriculostomy (ETV).
Background: Informed consent is a crucial aspect of modern medicine, but it can be challenging due to the complexity information involved. Mixed reality (MR) has emerged as promising technology improve communication. However, there lack comprehensive research on impact MR medical informed consent. The proposed protocol provides solid foundation for conducting future investigations and developing MR-based protocols that enhance patients’ understanding engagement in decision-making process....
Study Design. Retrospective cohort. Objective. To evaluate the impact of semaglutide treatment for Type 2 Diabetes Mellitus (T2DM) on risk short-term (<6 months) postoperative complications in patients undergoing primary cervical spine decompression and fusion (CSDF). Summary Background Data. Semaglutide, a GLP-1 receptor agonist, is gaining popularity as weekly injectable medication T2DM obesity. Existing research indicates that higher levels HbA1c obesity are linked to fewer positive...