A5060195279- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Head and Neck Surgical Oncology
- Neurosurgical Procedures and Complications
- Cancer, Hypoxia, and Metabolism
- Diversity and Career in Medicine
- Vascular Malformations Diagnosis and Treatment
- Lung Cancer Research Studies
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Palliative Care and End-of-Life Issues
- Surgical Simulation and Training
- Spinal Fractures and Fixation Techniques
- Cancer Genomics and Diagnostics
- Anatomy and Medical Technology
- Spine and Intervertebral Disc Pathology
- Epigenetics and DNA Methylation
- Cervical and Thoracic Myelopathy
- Pancreatic and Hepatic Oncology Research
- Spinal Dysraphism and Malformations
- Management of metastatic bone disease
Johns Hopkins University
2015-2025
Johns Hopkins Medicine
2014-2025
Johns Hopkins Hospital
2014-2025
Hospital Clínic de Barcelona
2022-2024
Sidney Kimmel Comprehensive Cancer Center
2022-2024
Universitat de Barcelona
2013-2024
Cancer Research Center
2022-2023
Sidney Kimmel Cancer Center
2022-2023
Mayo Clinic in Florida
2019
Neurological Surgery
2014-2019
Abstract BACKGROUND: A craniotomy with direct cortical/subcortical stimulation either awake or under general anesthesia (GA) present 2 approaches for removing eloquent region tumors. With a reported higher prevalence of intraoperative seizures occurring during resections perirolandic lesions, oftentimes, surgery GA is chosen these lesions. OBJECTIVE: To evaluate single-surgeon's experience craniotomies (AC) vs resecting perirolandic, eloquent, motor-region gliomas. METHODS: Between 2005 and...
Surgical simulation using postmortem human heads is one of the most valid strategies for neurosurgical research and training. The authors customized an embalming formula that provides optimal retraction profile lifelike physical properties while preventing microorganism growth brain decay simulations in cadavers. They studied compared its use with standard processing techniques: cryopreservation formaldehyde-based embalming.Eighteen specimens were prepared simulation: 6 formaldehyde...
Cost effectiveness has become an important factor in the health care system, requiring surgeons to improve efficacy of procedures while reducing costs. An awake craniotomy (AC) with direct cortical stimulation (DCS) presents one method resect eloquent region tumors; however, some authors assert that this procedure is expensive alternative surgery under general anesthesia (GA) neuromonitoring.To evaluate cost and clinical outcomes between AC GA patients.Retrospective analysis a cohort 17...
Endoscopic skull base surgery has become increasingly popular among the community, with improved illumination and angled visualization potentially improving tumor resection rates. Intraoperative MRI (iMRI) is used to detect residual disease during course of resection. This study an investigation utility 3-T iMRI in combination transnasal endoscopy regard gross-total (GTR) pituitary macroadenomas.The authors retrospectively reviewed all endoscopic transsphenoidal operations performed Advanced...
Background Perirolandic motor area gliomas present invasive eloquent region tumors within the precentral gyrus that are difficult to resect without causing neurologic deficits. Study Aims This study evaluates role of awake craniotomy and mapping on outcome extent resection (EOR) tumor in perirolandic region. It also analyzes preoperative risk factors for intraoperative seizures. Methods We evaluated 57 patients who underwent an a glioma. Patients had positive (PM) or identification regions...
Oligodendrogliomas present challenges in management despite their favorable prognosis. Optimal therapeutic strategies are not well-established. We aimed to characterize current practice patterns and identify areas of discordance oligodendroglioma management. A 20-question survey was distributed February-July 2023 four professional neurosurgery/neuro-oncology societies assess practices The collected data on demographics, diagnostic practices, treatment decisions. Data analysis performed using...
OBJECTIVE Brain metastases (BMs) are the most common CNS tumors, yet their prevalence is difficult to determine. Most studies only report synchronous metastases, which make up a fraction of all BMs. The authors incidence and prognosis patients with metachronous BMs over decade. METHODS Study data were obtained from TriNetX Research Network. Patients included if they had primary cancer diagnosis BM diagnosis, occurring between January 1, 2013, 2023. Metachronous was defined as diagnosed more...
Abstract Background Glioblastomas (GBMs) are the main primary brain tumors in adults with almost 100% recurrence rate. Patients lateral ventricle proximal GBMs (LV-GBMs) exhibit worse survival compared to distal locations for unknown reasons. One hypothesis is proximity of these cerebrospinal fluid (CSF) and its chemical cues that can regulate cellular phenotype. We therefore investigated role CSF on GBM gene expression a CSF-induced gene, SERPINA3, malignancy vitro vivo. Methods utilized...
BACKGROUND Spinal arachnoid webs (SAWs) are rare pathologies of the spinal meninges often associated with syringomyelia and radiographic “scalpel sign.” Patients can experience pain, numbness, gait disturbances, or no symptoms at all. They typically diagnosed via magnetic resonance imaging treated laminectomy excision. OBSERVATIONS A 61-year-old male presented after a mechanical fall had an incidentally discovered SAW on imaging. He was initially asymptomatic therefore conservatively...