- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Spinal Cord Injury Research
- Management of metastatic bone disease
- Traumatic Brain Injury and Neurovascular Disturbances
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Aortic Disease and Treatment Approaches
- Ultrasound Imaging and Elastography
- Spinal Dysraphism and Malformations
- Ultrasound and Hyperthermia Applications
- Surgical Simulation and Training
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Cerebrospinal fluid and hydrocephalus
- Ocular Oncology and Treatments
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Vascular Malformations Diagnosis and Treatment
- Automotive and Human Injury Biomechanics
- Trauma Management and Diagnosis
- Photoacoustic and Ultrasonic Imaging
- Spinal Hematomas and Complications
- Neurofibromatosis and Schwannoma Cases
Johns Hopkins Medicine
2021-2025
Johns Hopkins University
2021-2025
Johns Hopkins Hospital
2022-2025
Robot-assisted pedicle screw placement is associated with greater accuracy, reduced radiation, less blood loss, shorter hospital stays, and fewer complications than freehand placement. However, it can be longer operative times an extended training period. We report the initial experience of a surgeon using robot system at academic medical center.We retrospectively reviewed all patients undergoing robot-assisted single tertiary care institution by 1 from 10/2017 to 05/2022. Linear regression,...
Oligodendrogliomas present challenges in management despite their favorable prognosis. Optimal therapeutic strategies are not well-established. We aimed to characterize current practice patterns and identify areas of discordance oligodendroglioma management. A 20-question survey was distributed February-July 2023 four professional neurosurgery/neuro-oncology societies assess practices The collected data on demographics, diagnostic practices, treatment decisions. Data analysis performed using...
Brachial plexus tumors represent a challenge for neurosurgeons because of complex anatomy, risks during surgery, and limited evidence-based guidance in managing these rare tumors. We aim to investigate the clinical characteristics, complications, neurological outcomes surgical resection benign brachial reviewed medical records patients diagnosed with at (Johns Hopkins Medical Institutes) from July 2014 April 2023. Of 123 screened patients, those who had were identified. A total 56 included....
Replicating spinal cord injury (SCI) in large animals is necessary for evaluating therapeutics potential human translation, yet there currently no commercial, standardized device inducing SCI. We present the fabrication and testing of a custom impactor producing repeatable contusion SCI porcine models. first designed built device. Mechanical modeling was subsequently utilized to calibrate our benchtop setup. Benchtop verification performed measure impact force post calibration. then used...
INTRODUCTION: Frailty is a known correlate of poor outcomes following spine surgery. However, long-term are not well-studied. METHODS: TriNetX Research Network was queried by CPT for patients undergoing the 13 most common surgeries. Patients were propensity score matched to control age, sex, and race. Kaplan-Meier plots used evaluate differences in survival Clavien-Dindo Grade IV complications (unplanned intubation, prolonged ventilation, pulmonary embolism, acute kidney failure, stroke,...
INTRODUCTION: Robotic-assisted posterior spinal fusion (PSF) increases the accuracy of pedicle screw insertion. Frailty and comorbidity indices assess a patient’s capacity to tolerate surgery, but performance these for patients undergoing robotic-assisted spine surgery has not been characterized. METHODS: A retrospective cohort aged 50 older primary PSF at single center between January 2022 December 2023 was identified. Multivariable logistic regressions compared ability mFI-5, CCI, ASA...
INTRODUCTION: Mild traumatic brain injury (mTBI) is a common with lasting sequalae. Little known about mTBI care pattern variations. METHODS: 92,406 patients were retrospectively identified from the ACS Trauma Quality Programs dataset. We performed hierarchical logistic regression to investigate associations of patient-level characteristics hospitalization. Among hospitalized patients, linear was constructed for LOS using hospitals as random effects term. Each hospital classified high-LOS...
INTRODUCTION: Following spinal cord injury (SCI), treatment includes vasopressors to elevate mean arterial pressure (MAP) preserve blood flow at the injury. However, this is based on limited understanding of how interact with vasculature. Specifically, α- and β-adrenergic receptors have been implicated in vasoconstriction vasodilation, respectively, central nervous system. Depending affinity pressors each receptor, differential effects may occur. METHODS: A T4-T6 laminectomy was performed...
INTRODUCTION: Prostate cancer with spinal metastases (PCSM) is associated high morbidity and mortality. The impact of somatic mutations on the prognosis metastases, however, remains unclear. METHODS: We conducted a retrospective analysis 68 PCSM patients at Johns Hopkins from 2013 to 2023, examining influence specific targeted therapies prognosis. Criteria included diagnosis available genetic profiling. Primary outcomes were overall survival (OS) rates, identification biomarkers,...
INTRODUCTION: Intramedullary spinal cord tumors (IMSCTs) are treated by maximal safe surgical resection, during which neurosurgeons often rely on motor-evoked potentials (MEPs) and direct wave (D-wave) neuromonitoring. However, the predictive value of changes in neuromonitoring for detecting motor outcomes is unclear. METHODS: All patients undergoing resection a primary IMSCT with MEP from 2003-2023 at tertiary care hospital were retrospectively identified. Pre- post-operative...
INTRODUCTION: Neurosurgical residency applicants are traditionally evaluated on metrics that do not reflect technical ability. While dexterity tests sometimes used, they reveal the internal processing behind a test outcome. Cognitive load (CL) can provide insight into bandwidth required to perform tasks and whether residual capacity exists for increasing task burden. The baseline change in pupil diameter (BCPD) be used calculate CL, providing insights mental effort decision-making processes....
Objective: To characterize variation in the treatment of patients with mild traumatic brain injury (mTBI) who were reasonable candidates for hospitalization, we investigated patient-level associations inpatient admission and hospital-level length stay (LOS). We further whether treated at high-LOS hospitals more likely to experience home discharge. Setting: Patients retrospectively identified from ACS TQIP dataset. Participants: A total 122 406 mTBI included. Design: performed hierarchical...
Damage to the thoracolumbar spine can confer significant morbidity and mortality. The Thoracolumbar Injury Classification Severity Score (TLICS) is used categorize injuries determine patients at risk of spinal instability for whom surgical intervention warranted. However, calculating this score constitute a bottleneck in triaging treating patients, as it relies on multiple imaging studies neurological examination. Therefore, authors sought develop validate deep learning model that...
Here we investigate the ability of low-intensity ultrasound (LIUS) applied to spinal cord modulate transmission motor signals.
Synthetic computed tomography (sCT) can be created from magnetic resonance imaging (MRI) utilizing newer software. sCT is yet to explored as a possible alternative routine CT (rCT). In this study, rCT scans and MRI-derived were obtained on cadaver. Morphometric analysis was performed comparing the 2 scans. The ExcelsiusGPS robot used place lumbosacral screws with both images.In total, 14 placed. All grade A Gertzbein-Robbins scale. mean surface distance difference between reconstructed...
BACKGROUND Spinal arachnoid webs (SAWs) are rare pathologies of the spinal meninges often associated with syringomyelia and radiographic “scalpel sign.” Patients can experience pain, numbness, gait disturbances, or no symptoms at all. They typically diagnosed via magnetic resonance imaging treated laminectomy excision. OBSERVATIONS A 61-year-old male presented after a mechanical fall had an incidentally discovered SAW on imaging. He was initially asymptomatic therefore conservatively...
Growing evidence suggests that piriform cortex resection during anterior temporal lobectomy is important for achieving good seizure outcome in mesial lobe epilepsy (mTLE). However, the relationship between and ablation MR-guided laser interstitial thermal therapy (MRgLITT) remains unclear.To determine whether of was associated with patients mTLE undergoing MRgLITT.We performed preablation postablation volumetric analyses hippocampus, amygdala, cortex, volumes who underwent MRgLITT at our...