A5013144530- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Ultrasound and Hyperthermia Applications
- Ultrasound Imaging and Elastography
- Congenital Anomalies and Fetal Surgery
- Aortic Disease and Treatment Approaches
- Spinal Dysraphism and Malformations
- Photoacoustic and Ultrasonic Imaging
- Intracranial Aneurysms: Treatment and Complications
- Spinal Cord Injury Research
- Cerebrovascular and Carotid Artery Diseases
- Spondyloarthritis Studies and Treatments
- Ultrasound in Clinical Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Neurobiology and Insect Physiology Research
- Shoulder Injury and Treatment
- Automotive and Human Injury Biomechanics
- Non-Invasive Vital Sign Monitoring
- Osteomyelitis and Bone Disorders Research
- Management of metastatic bone disease
- Surgical Simulation and Training
- Cellular transport and secretion
- Traumatic Brain Injury Research
- Musculoskeletal pain and rehabilitation
Johns Hopkins Medicine
2022-2025
Johns Hopkins University
2022-2025
University of Baltimore
2023
Vanderbilt University Medical Center
2021
Robot-assisted pedicle screw placement is associated with greater accuracy, reduced radiation, less blood loss, shorter hospital stays, and fewer complications than freehand placement. However, it can be longer operative times an extended training period. We report the initial experience of a surgeon using robot system at academic medical center.We retrospectively reviewed all patients undergoing robot-assisted single tertiary care institution by 1 from 10/2017 to 05/2022. Linear regression,...
INTRODUCTION: Robotic-assisted posterior spinal fusion (PSF) increases the accuracy of pedicle screw insertion. Frailty and comorbidity indices assess a patient’s capacity to tolerate surgery, but performance these for patients undergoing robotic-assisted spine surgery has not been characterized. METHODS: A retrospective cohort aged 50 older primary PSF at single center between January 2022 December 2023 was identified. Multivariable logistic regressions compared ability mFI-5, CCI, ASA...
Here we investigate the ability of low-intensity ultrasound (LIUS) applied to spinal cord modulate transmission motor signals.
Synthetic computed tomography (sCT) can be created from magnetic resonance imaging (MRI) utilizing newer software. sCT is yet to explored as a possible alternative routine CT (rCT). In this study, rCT scans and MRI-derived were obtained on cadaver. Morphometric analysis was performed comparing the 2 scans. The ExcelsiusGPS robot used place lumbosacral screws with both images.In total, 14 placed. All grade A Gertzbein-Robbins scale. mean surface distance difference between reconstructed...
OBJECTIVE Few large studies have investigated the factors and outcomes related to concomitant injuries occurring alongside mild traumatic brain injury (mTBI) after motor vehicle collisions (MVCs). Thus, objective of this study was assess whether MVC characteristics predict which patients with mTBI will whiplash injury, affects care utilization for these patients. METHODS This retrospective cohort included 22,213 identified from American College Surgeons Trauma Quality Programs dataset. A...
OBJECTIVE The authors investigated the predictors of cost admission (CoA) for robot-assisted pedicle screw placement to assess value robotic systems in spine operations. METHODS Demographic, operative, and postoperative variables were retrospectively collected from 506 patients undergoing surgery utilizing ExcelsiusGPS robot at two high-volume tertiary care centers 2017 2023. Perioperative parameters evaluated against total hospital Kruskal-Wallis Wilcoxon rank-sum tests followed by...
Low-intensity focused ultrasound (LIFU) uses ultrasonic pulsations at lower intensities than and is being tested as a reversible precise neuromodulatory technology. Although LIFU-mediated blood-brain barrier (BBB) opening has been explored in detail, no standardized technique for blood-spinal cord (BSCB) established to date. Therefore, this protocol presents method successful BSCB disruption using LIFU sonication rat model, including descriptions of animal preparation, microbubble...
ABSTRACT The synaptic cleft manifests enriched glycosylation, with structured glycans coordinating signaling between presynaptic and postsynaptic cells. Glycosylated ligands orchestrating communication are tightly regulated by secreted glycan-binding lectins. Using the Drosophila neuromuscular junction (NMJ) as a model glutamatergic synapse, we identify new Ca2+-binding (C-type) lectin, Lectin-galC1 (LGC1), which modulates function neurotransmission strength. We find that LGC1 is in...
Ultrasound technology can provide high-resolution imaging of blood flow following spinal cord injury (SCI). Blood may improve critical care management SCI, yet its duration is limited clinically by the amount contrast agent injection required for high-resolution, continuous monitoring. In this study, we aim to establish non-contrast ultrasound as a translatable technique via comparison contrast-based methods and measuring spatial distribution after SCI. A rodent model contusion SCI at T12...
INTRODUCTION: Stem cells promote spinal cord injury (SCI) recovery by secreting paracrine factors that orchestrate endogenous healing mechanisms. However, effects in clinical trials are modest and there no approved stem cell therapies to treat SCI. Major barriers include washout, immune attack, oncogenic potential. METHODS: ITBs were implanted three pigs. One pig received a cell-loaded ITB without (Cells), another with (Cells + SCI), sham (SCI). SCIs induced weight drop at T5. cranial the...
While deep learning has catalyzed breakthroughs across numerous domains, its broader adoption in clinical settings is inhibited by the costly and time-intensive nature of data acquisition annotation. To further facilitate medical machine learning, we present an ultrasound dataset 10,223 Brightness-mode (B-mode) images consisting sagittal slices porcine spinal cords (N=25) before after a contusion injury. We additionally benchmark performance metrics several state-of-the-art object detection...
<h3>Background</h3> Robotic platforms have increased in sophistication for pedicle screw placement. Here, we review our institutional experience using ExcelsiusGPS to assess the accuracy rate of placement throughout spine and characterize predictors inaccuracy. <h3>Study Design</h3> Retrospective cohort study. <h3>Methods</h3> Patients from 2017 2022 undergoing spinal fusion surgery with ExelsiusGPS-assisted implantation at a single tertiary center were retrospectively identified. Patient...
BACKGROUND AND OBJECTIVES: Flow diversion of intracranial aneurysms results in high occlusion rates. However, 10% to 20% remain persistently filling at 1 year. Often, these are retreated, but benefits retreatment not well established. A better understanding the long-term rupture risk after flow is needed. METHODS: Our institutional database 974 cases was queried for saccular clinoidal, ophthalmic, and communicating segments internal carotid artery treated with pipeline embolization device...
INTRODUCTION: Flow diversion of intracranial aneurysms results in high occlusion rates. However, 10-20% remain persistently filling on one year angiography. Often, these are retreated, but risks and benefits retreatment not well established. Calculating benefit requires a better understanding rupture risk flow diverted aneurysms, which is sufficiently METHODS: Our single institution database 1000 cases was queried for saccular the clinoidal, ophthalmic, communicating segments internal...
Abstract Ultrasound technology can provide high-resolution imaging of blood flow following spinal cord injury (SCI). Blood may improve critical care management SCI, yet is limited clinically by the invasive nature contrast agent injection required for high-resolution, continuous monitoring. In this study, we aim to establish non-contrast ultrasound as a translatable technique via comparison contrast-based methods and measuring spatial distribution after SCI. A rodent model contusion SCI at...