A5103261263- Pituitary Gland Disorders and Treatments
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Scoliosis diagnosis and treatment
- Intracranial Aneurysms: Treatment and Complications
- Glioma Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Head and Neck Surgical Oncology
- Traumatic Brain Injury and Neurovascular Disturbances
- Adrenal and Paraganglionic Tumors
- Vascular Malformations Diagnosis and Treatment
- Cervical and Thoracic Myelopathy
- Cerebrospinal fluid and hydrocephalus
- Management of metastatic bone disease
- Trauma and Emergency Care Studies
- History of Medical Practice
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Analysis
- Spinal Hematomas and Complications
- Spinal Cord Injury Research
- Neurogenesis and neuroplasticity mechanisms
- Cerebral Venous Sinus Thrombosis
Harvard University
2015-2025
Brigham and Women's Hospital
2016-2025
Neurological Surgery
2011-2023
Civil Hospital Karachi
2023
Imperial College London
2022
Drexel University
2021
Leiden University Medical Center
2021
Dana-Farber Cancer Institute
2020
Dana-Farber Brigham Cancer Center
2020
Boston University
2019
Mesoporous silica-coated hollow manganese oxide (HMnO@mSiO(2)) nanoparticles were developed as a novel T(1) magnetic resonance imaging (MRI) contrast agent. We hypothesized that the mesoporous structure of nanoparticle shell enables optimal access water molecules to core, and consequently, an effective longitudinal (R(1)) relaxation enhancement protons, which value was measured be 0.99 (mM(-1)s(-1)) at 11.7 T. Adipose-derived mesenchymal stem cells (MSCs) efficiently labeled using...
The average hospital cost for shunt infection treatment is $50,000, making it the most financially costly implant-related in United States. We set out to determine whether introduction of antibiotic-impregnated shunts (AISs) our practice has decreased incidence or infection-related costs at institution.Clinical and billing records pediatric patients undergoing cerebrospinal fluid (CSF) insertion a single institution from April 2001 December 2006 were retrospectively reviewed. Eighteen months...
Acute hydrocephalus is a well-known sequela of aneurysmal subarachnoid hemorrhage (SAH). Controversy exists about whether open microsurgical methods serve to reduce shunt dependency compared with endovascular techniques.To determine predictors shunt-dependent and functional outcomes after SAH.A total 471 patients who were part prospective, randomized, controlled trial from 2003 2007 retrospectively reviewed. All variables including demographic data, medical history, treatment, imaging,...
Spinal arteriovenous fistulas (AVFs) and malformations (AVMs) are rare, complex spinal vascular lesions that challenging to manage. Recently, understanding of these has increased thanks neuroimaging technology. Published reports surgical results clinical outcome limited small series. The authors present a large contemporary series patients with AVFs AVMs who were treated at Barrow Neurological Institute in Phoenix, Arizona.Retrospective detailed review prospective database was performed for...
Microscopic and endoscopic transsphenoidal approaches to the sellar are well established. Surgical freedom is an important skull base principle that can be measured objectively used compare approaches.To surgical of 4 sella turcica aid in approach selection.Four were performed on 8 silicon-injected cadaveric heads. was determined with stereotactic image guidance using previously established techniques. The results presented as area angular (angle attack) axial sagittal planes.Mean total...
Endoscopic skull base surgery has become increasingly popular among the community, with improved illumination and angled visualization potentially improving tumor resection rates. Intraoperative MRI (iMRI) is used to detect residual disease during course of resection. This study an investigation utility 3-T iMRI in combination transnasal endoscopy regard gross-total (GTR) pituitary macroadenomas.The authors retrospectively reviewed all endoscopic transsphenoidal operations performed Advanced...
The objective of this study was to investigate whether disparities in access high-volume centers for neurooncological care existed the United States 1988-2005.A retrospective analysis Nationwide Inpatient Sample (1988-2005) performed, with additional factors incorporated from Area Resource File (2006). International Classification Diseases, Ninth Revision, diagnosis/procedure coding used identify patients. High-volume were defined as those > or =50 neurosurgical cases per year. Patients >18...
Indocyanine green (ICG) angiography is commonly used to map the vascular configuration of cerebral arteriovenous malformations (AVMs) during resection.To determine whether ICG improves rates resection and clinical outcomes.A retrospective chart review was done for all patients undergoing an AVM by senior author (R.F.S.) between 2007 2011. Operative reports, hospital records, radiographic imaging were use ICG, incidence residual disease, total 130 cases (56 74 non-ICG) identified. Average...