A5038190499- Influenza Virus Research Studies
- Machine Learning in Bioinformatics
- Circadian rhythm and melatonin
- Neuroscience and Neuropharmacology Research
- thermodynamics and calorimetric analyses
- Ion channel regulation and function
- Spaceflight effects on biology
- vaccines and immunoinformatics approaches
- Immune Response and Inflammation
- interferon and immune responses
- Genetics, Aging, and Longevity in Model Organisms
- Nicotinic Acetylcholine Receptors Study
University of Connecticut
2023
Birla Institute of Technology and Science, Pilani
2022
Birla Institute of Technology and Science - Hyderabad Campus
2022
Melatonin is known to promote sleep, but its underlying molecular mechanisms remain poorly understood. Using CBA/CaJ mice, a strain capable of melatonin synthesis, we explored the roles BK channel (Slo1) and receptor MT1 in regulating sleep behavior action potentials suprachiasmatic nucleus (SCN). Global knockout Slo1 or reduced REM NREM increased wakefulness, broadened while abolishing afterhyperpolarization SCN neurons. These effects were primarily exclusively observed during subjective...
Nonstructural (NS1) protein is mainly involved in virulence and replication of several viruses, including influenza virus A (H1N1); surveillance the latter started India 2009. The objective this study was to identify new substitutions NS1 from (H1N1) pandemic 2009 (pdm09) strain isolated India.The sequences proteins A(H1N1) pdm09 strains were obtained publicly available databases. Multiple sequence alignment phylogeny analyses performed confirm "consistent substitutions" on H1N1 Indian...
Comparative analyses of locomotor behavior and cellular electrical properties between wild-type mutant
The routine influenza (H1N1) surveillance in India started almost a decade ago. fluctuation the number of deaths and cases different Indian states over last presumably indicated possible changes viral sequence immune response host. To track these changes, we have chosen NS1 protein that invades host antiviral response. Objective this study was to identify recent mutations on from isolates. sequences proteins H1N1 strains isolated were obtained publicly available databases. Multiple...