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Research Areas
- Erythrocyte Function and Pathophysiology
- Immune cells in cancer
- Phagocytosis and Immune Regulation
Stanford University
2024
Atherosclerosis is an inflammatory disorder responsible for cardiovascular disease. Reactivation of efferocytosis, the phagocytic removal cells by macrophages, has emerged as a translational target atherosclerosis. Systemic blockade key 'don't-eat-me' molecule, CD47, triggers engulfment apoptotic vascular tissue and potently reduces plaque burden. However, it also induces red blood cell clearance, leading to anemia. To overcome this, we previously developed macrophage-specific nanotherapy...
10.1038/s41467-024-52005-1
article
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cc-by-nc-nd
Nature Communications
2024-09-13
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