A5015539189- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Airway Management and Intubation Techniques
- Lung Cancer Treatments and Mutations
- Crystallization and Solubility Studies
- Congenital Diaphragmatic Hernia Studies
- Crystal Structures and Properties
- Solid-state spectroscopy and crystallography
- Nonlinear Optical Materials Research
- Perovskite Materials and Applications
- Myasthenia Gravis and Thymoma
- X-ray Diffraction in Crystallography
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Cancer Genomics and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Respiratory Support and Mechanisms
- Pulmonary Hypertension Research and Treatments
- RNA modifications and cancer
- Medical Imaging and Pathology Studies
- Nanocluster Synthesis and Applications
- Graph Theory and Algorithms
- Advanced battery technologies research
Universidad del Noreste
2024
Qufu Normal University
2022-2024
Shanghai Zhabei District Shibei Hospital
2014-2024
Capital Normal University
2024
East China Normal University
2024
Jiangsu University of Technology
2022-2023
Guangzhou Medical University
2012-2022
First Affiliated Hospital of Guangzhou Medical University
2011-2022
State Key Laboratory of Respiratory Disease
2011-2022
National Clinical Research Center for Digestive Diseases
2016-2022
Objective. The purposes of this study were to evaluate the feasibility, safety, and advantages nonintubated video-assisted thoracoscopic surgery (VATS) under epidural anesthesia, by comparing with performance conventional approaches. Patients methods. A total 354 patients (245 men 109 women) recruited in study. surgical procedures included bullae resection, pulmonary wedge lobectomy. anesthetic technique (epidural vs general) was selected randomly. who underwent VATS anesthesia comprised...
To comparatively assess the impact of non-intubated intravenous anaesthesia with spontaneous ventilation (NIIASV) versus intubated single-lung mechanical (IASLV) on early outcomes video-assisted thoracoscopic (VATS) anatomical resection non-small-cell lung cancer (NSCLC).A total 339 patients NSCLC undergoing VATS (282 lobectomies and 57 segmentectomies) between December 2011 2014 were included for analysis divided into two groups according to type: NIIASV (151 patients) IASLV (188 patients)....
BACKGROUND. Current clinical management of patients with pulmonary nodules involves either repeated low-dose CT (LDCT)/CT scans or invasive procedures, yet causes significant patient misclassification. An accurate noninvasive test is needed to identify malignant and reduce unnecessary tests.
Currently, organic–inorganic hybrid cuprous-based halides are receiving substantial attention for their eco-friendliness, distinctive structures, and outstanding photophysical properties. Nevertheless, most of the reported demand deep ultraviolet excitation with a narrow range that can meet commercial requirement. Herein, zero-dimensional (0D) halide (C4H10N)4Cu4I8 single crystals (SCs) were synthesized, an ultrabroad band ranging 260–450 nm greenish-yellow emission peaking at 560 nm....
Problems associated with intubation, chest drainage and urinary catheterization can have a negative impact on patient's recovery after thoracic surgery. We therefore evaluated the feasibility of new tubeless (spontaneous ventilation without tracheal catheterization, no post-operative drain placement) approach to perform video-assisted thoracoscopic surgery (VATS) for small pulmonary nodules (SPN) less than 2cm in diameter.From 1 January 2012 31 December 2014, 34 patients SPNs were treated...
To design nonlinear optical (NLO) materials, we focused on combinations of d10 metal cation (Cd2+)-based chloride and morpholine molecules to form organic-inorganic hybrids. The O containing lone-pair electrons can be integrated with Cd2+ by a ligand-to-metal charge transfer (LMCT) strategy build acentric structures benefiting from the second-order Jahn-Teller effect. Introduction high-electronegativity chlorine make polyhedrons crystals more distorted conducive strong second harmonic...
In modern society, the investigation of highly efficient photoluminescent bulk materials with excitation-induced tunable multicolor luminescence and multiexciton generation (MEG) is great significance to information security application optoelectronic devices. this study, two Cu-based halide crystals (C4H10NO)4Cu2Br5·Br (C4H10NO)4Cu2I5·I·H2O, respectively, one-dimensional structures were grown by a solvent evaporation method. Unexpectedly, (C4H10NO)4Cu2I5·I·H2O displayed dual-color...
To explore the feasibility of complete video-assisted thoracoscopic surgery (c-VATS) following neoadjuvant therapy (chemotherapy, targeted and radiotherapy, either alone or in combination) for treatment patients with non-small cell lung cancer (NSCLC).The clinical data 43 NSCLC undergoing c-VATS were retrospectively analyzed, including preoperative functional indicators, staging, concurrent diseases, surgical techniques, operation time, number lymph nodes dissected postoperative drainage...
This study aims to explore the feasibility and safety of video-assisted thoracic surgery (VATS) double sleeve lobectomy in patients with non-small lung cell cancer (NSCLC).Between June 2012 August 2014, 13 NSCLC underwent thoracoscopic mediastinal lymphadenectomy at three institutions. A retrospective analysis clinical characteristics, operative data, postoperative events follow-up was performed.Thirteen (median age, 60 years; range, 43-67 years) lobectomy. There were no conversions...
Background: The aim of this study was to reveal the short-term outcomes video-assisted thoracoscopic surgery (VATS) segmentectomy without tracheal intubation compared with intubated general anesthesia one-lung ventilation (OLV). Methods: We performed a retrospective review our institutional database consecutive 140 patients undergoing VATS anatomical from July 2011 June 2015. Among them, 48 were treated using combination thoracic epidural (TEA), intrathoracic vagal blockade, and sedation...
Zero-dimensional (0D) organic–inorganic hybrid halides present many fascinating photophysical properties for promising optoelectronic applications such as light-emitting diodes (LEDs), X-ray imaging, photodetectors, and anticounterfeiting. Herein, a centimeter-sized single crystal (C6H10N2)2MnCl6·2H2O with 0D perovskite structure was obtained via solvent evaporation method. A bright red emission at 618 nm larger Stokes shift of more than 300 long fluorescence lifetime 6.21 ms were measured....
To study one-lung respiration during VATS wedge resection of bullae and pulmonary nodules with nontracheal intubation, to explore the changes vital signs when patients return two-lung ventilation.Twenty-two normal cardiopulmonary function absence contraindications epidural anesthesia were included in this study. or was performed. 0.5% Ropivacain administrated for (T8-9), 2 mL 2% lidocaine used local anesthetic block intrathoracic vagus nerves. The BIS value maintained between 50 70 by...
To explore the feasibility and safety of complete video-assisted thoracoscopic surgery (C-VATS) under non-intubated anesthesia for resection anatomic pulmonary segments in treatment early lung cancer (T1N0M0), benign diseases metastases.The clinical data patients undergoing using C-VATS First Affiliated Hospital Guangzhou Medical University from July 2011 to November 2013 were retrospectively analyzed evaluate this technique.The procedures successfully completed 15 patients, including four...
Tumor mutation burden (TMB) serves as an effective biomarker predicting efficacy of mono-immunotherapy for non-small cell lung cancer (NSCLC). Establishing a precise TMB model is essential to select which populations are likely respond immunotherapy or prognosis and maximize the benefits treatment. In this study, available Formalin-fixed paraffin embedded tumor tissues were collected from 499 patients with NSCLC. Targeted sequencing 636 related genes was performed, calculated. Distribution...
Introducing electronegative species into organic constituents was considered to be one effective strategy for adjusting crystal symmetry and designing new nonlinear optical (NLO) materials. By substitution of C4 in piperidine (C5H11N) with oxygen, morpholine (C4H9NO) easily obtained. Therefore, design NLO crystals, we focused on combinations stereochemically active lone-pair (SCALP) cation (Pb2+)-based chloride bromide molecules. In this work, two lead halide hybrid perovskite (C4H10NO)PbX3...
Abstract Background The purpose of the present study was to assess value matrix metalloproteinase (MMP)‐2 and MMP‐9 expression other potential prognostic factors in predicting clinical outcome patients after definitive surgery for pathologic stage IA non‐small cell lung cancer (NSCLC). Methods One hundred forty‐six consecutive non‐selected who underwent NSCLC were included this study. Formalin‐fixed paraffin‐embedded specimens stained MMP‐2 MMP‐9, which statistically evaluated their...
Abstract Background The purpose of this study was to investigate the role heat shock protein 60 (HSP60) in clinical pathology lung adenocarcinoma, and explore whether expression HSP60 can act as an independent predictor for tumor relapse prognosis after radical resection adenocarcinoma. Methods Paraffin sections adenocarcinoma tissues were collected from 103 patients. Using immunohistochemistry, levels detected. correlations between clinicopathological parameters well statistically analyzed....
To explore the effectiveness of video-assisted thoracoscopic surgery (VATS) bronchial sleeve resection and reconstruction.The clinical data patients who had received VATS lobectomy in our center from January 2008 to February 2015 were retrospectively analyzed.Totally 118 (105 men 13 women) lobectomy. The procedures included right upper lobe (n=59), middle (n=7), lower (n=8), left (n=34), (n=10). lesions confirmed be squamous cell carcinoma (n=68), adenocarcinoma (n=16), mucoepidermoid...
Organic-inorganic hybrid Pb-halide perovskites have attracted tremendous interest due to their potential application in photovoltaic and optoelectronic fields. However, the toxicity poor stability of become key bottlenecks toward future commercialization industrialization. Therefore, this work, two novel lead-free perovskite nonlinear optical (NLO) crystals (2-AMP)2BiX7·H2O (X = Cl, Br) with high were successfully synthesized. Both belong orthorhombic P212121 space group, displaying a...
Abstract Colorectal cancer (CRC) stands as a major contributor to cancer-related fatalities within China. There is an urgent need identify accurate biomarkers for recurrence predicting in CRC. Reduced representation bisulfite sequencing was used perform comparative analysis of methylation profiles tissue samples from 30 non-recurrence patients with Least absolute shrinkage and selection operator method performed select the differential regions (DMRs) built DNA classifier recurrence. Based on...
Background. The objectives of this study were to report the surgical techniques and clinical outcome thoracoscopic half carina resection bronchial sleeve for central lung cancer. Methods. Between January 2011 November 2012, 675 patients with cancer underwent radical surgery by thoracoscopy, 49 (7.3%) resection. Among patients, 20 (41%) received lobectomy. Perioperative variables postoperative outcomes these cases analyzed evaluate technical feasibility safety operation. Results. In one...