A5028392761- Cardiovascular and exercise physiology
- Cardiovascular Effects of Exercise
- Chemotherapy-induced cardiotoxicity and mitigation
- Long-Term Effects of COVID-19
- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Thermal Regulation in Medicine
- Pulmonary Hypertension Research and Treatments
- Lymphatic System and Diseases
- Acute Ischemic Stroke Management
- Medical and Biological Ozone Research
- Peripheral Artery Disease Management
- Mitochondrial Function and Pathology
- Qualitative Research Methods and Ethics
- Cardiac Arrhythmias and Treatments
- Geographies of human-animal interactions
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Imaging and Diagnostics
- Birth, Development, and Health
- Atrial Fibrillation Management and Outcomes
Baker Heart and Diabetes Institute
2021-2024
University of Glasgow
2005
Breast cancer survivors treated with anthracycline-based chemotherapy (AC) have increased risk of functional limitation and cardiac dysfunction. We conducted a 12-month randomized controlled trial in 104 patients early-stage breast scheduled for AC to determine whether 12 months exercise training (ExT) could attenuate disability (primary end point), improve cardiorespiratory fitness (VO2peak), prevent dysfunction.Women 40 75 years age stage I III were 3 4 days per week aerobic resistance ExT...
Increased left atrial (LA) size and reduced LA function have been associated with heart failure fibrillation (AF) in at-risk populations. However, remodeling has also exercise training the relationship between fitness, size, not defined across fitness spectrum. In a cross-sectional study of 559 ostensibly healthy participants, comprising 304 males (mean age, 46 ± 20 yr) 255 females 47 15 yr), we sought to define cardiorespiratory (CRF), function. We aimed interrogate sex differences factors...
Coronavirus disease-19 (COVID-19) has been associated with cardiac pathology raising the possibility of serious arrhythmias among athletes returning to competition post infection.1–3 Several studies have assessed function and structure in post-COVID-19 infection but challenged by selection bias, lack an appropriate control group none included comprehensive imaging, exercise testing, clinical electrophysiology.2,4–7 We recruited every player from a squad professional basketballers involved...
BACKGROUND: Survivors of allogeneic stem cell transplant (SCT) receive intensive cancer treatments that are associated with cardiovascular dysfunction. Markers vascular age can indicate early signs adverse (cardio)vascular changes; however, the impact SCT on these makers is unknown. We aimed to determine short (3 months) and longer-term (≥2 years) effect markers in hematologic survivors compared an age-matched noncancer control group. METHODS: The short-term effects SCT, (aortic compliance,...
Background and Aims: We wanted to determine the prevalence of atrial fibrillation (AF) in a community based cross sectional study greater Glasgow how current anti thrombotic management compares published guidelines. Methods: 1466 patients with AF were identified General Practices our 1008 consented take part. Their demographic details medical history recorded. Results: (mean age 73.4; 55% female) identified, community, giving 1%. 53% on warfarin therapy. Of those not receiving warfarin, only...
HISTORY: A 50-year-old male suffered a cardiac arrest after an endurance cycling event. After prompt cardiopulmonary resuscitation and electrical cardioversion, coronary angiography demonstrated severe intermediate vessel stenosis treated with percutaneous intervention. Echocardiography showed mildly reduced Left Ventricular (LV) systolic function wall motion abnormalities discordant angiography. Magnetic Resonance Imaging interventricular septum, mid-inferolateral LV apex hypokinesis....
Abstract Background A hypertensive response to exercise (HRE) is considered indicative of increased arterial stiffness (1). However, HRE common in individuals with high cardiorespiratory fitness (CRF) (2), which we hypothesize due stroke volume (SV) and cardiac output (Qc). Purpose This study compared differences CRF peak-exercise SV (SVpeak) Qc (Qcpeak) according absolute workload-indexed definitions hypertension women. Methods Women free overt CVD (n=142; 52±8years, BMI: 26.3±4.5kg/m2)...
Introduction: Post-acute COVID-19 sequalae (PASC) is a poorly understood constellation of symptoms that persist or emerge following the post-viral convalescent period. We sought to comprehensively evaluate cardiac and autonomic function deconditioning as possible contributors PASC associated fatigue. Methods: Thirty individuals with (20F:10M; 41±11yrs; 137-730 days post-infection) prospectively underwent measures (heart rate [HR] muscle sympathetic nerve activity [MSNA] response passive...
62 year old male was referred for evaluation of exertional breathlessness, predominantly when commuting to work by bicycle. There no associated chest pain, palpitations, syncope or family history cardiovascular disease. He had untreated hypertension, a remote hairy cell leukemia treated with cladribine in remission and polycythemia rubra vera venesection pegylated-interferon therapy. Trans-thoracic echocardiogram demonstrated normal biventricular size systolic function valvular function....