Tomás A. Peña

ORCID: 0009-0003-3201-743X
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About
Contact & Profiles
Research Areas
  • Fermentation and Sensory Analysis
  • Fungal and yeast genetics research
  • Yeasts and Rust Fungi Studies
  • Plant Pathogens and Fungal Diseases
  • Horticultural and Viticultural Research
  • Mycorrhizal Fungi and Plant Interactions
  • Fungal Biology and Applications
  • Astronomy and Astrophysical Research
  • Gamma-ray bursts and supernovae
  • Stellar, planetary, and galactic studies
  • Microbial Metabolism and Applications
  • Tea Polyphenols and Effects

Universidad de Santiago de Chile
2020-2025

Millennium Institute for Integrative Biology
2020-2025

Millennium Science Initiative
2020-2021

<title>Abstract</title> The nature and formation history of our Galaxy's largest most enigmatic stellar cluster, known as Omega Centauri (oCen) remains debated. Here, we offer a novel approach to disentangling the complex populations within oCen based on phylogenetics methodologies from evolutionary biology. These include Gaussian Mixture Model Neighbor-Joining clustering algorithms applied set chemical abundances members. Instead using classical in astronomy grouping them into separate...

10.21203/rs.3.rs-5806252/v1 preprint EN cc-by Research Square (Research Square) 2025-01-22

Lager beer is traditionally fermented using Saccharomyces pastorianus. However, the limited availability of lager yeast strains restricts potential range profiles. Recently, eubayanus showed to impart novel aromas beer, with slower fermentation rates than commercial strains. Here, we applied experimental evolution nine S. three different selective conditions generate improved fermentative environments. We observed environment-dependent fitness changes across strains, ethanol-enriched media...

10.1093/femsyr/foaf004 article EN cc-by-nc-nd FEMS Yeast Research 2025-01-28

Species delineation in microorganisms is challenging due to the limited markers available for accurate species assignment. Here, we applied an integrative taxonomy approach, combining extensive sampling, whole-genome sequence-based classification, phenotypic profiling, and assessment of interspecific reproductive isolation. Our work reveals presence a distinct Saccharomyces lineage Nothofagus forests coastal Patagonia. This lineage, designated chiloensis sp. nov., exhibits 7% genetic...

10.1371/journal.pgen.1011396 article EN cc-by PLoS Genetics 2024-09-06

Evaluating domestication signatures beyond model organisms is essential for a thorough understanding of the genotype-phenotype relationship in wild and human-related environments. Structural variations (SVs) can significantly impact phenotypes playing an important role physiological adaptation species to different niches, including during domestication. A detailed characterization fitness consequences these genomic rearrangements, however, still limited non-model systems, largely due paucity...

10.1128/msystems.01058-23 article EN cc-by mSystems 2023-12-12

Summary Although the typical genomic and phenotypic changes that characterize evolution of organisms under human domestication syndrome represent textbook examples rapid evolution, molecular processes underpin such are still poorly understood. Domesticated yeasts for brewing, where short generation times large plasticity were attained in a few generations selection, prime examples. To experimentally emulate lager yeast process, we created genetically complex (panmictic) artificial population...

10.1111/1751-7915.13803 article EN Microbial Biotechnology 2021-03-23

Abstract Most organisms belonging to the Saccharomycotina subphylum have high genetic diversity and a vast repertoire of metabolisms lifestyles. Lachancea cidri is an ideal yeast model for exploring interplay between genetics, ecological function evolution. diverged from Saccharomyces lineage before whole‐genome duplication distributed across South Hemisphere, displaying important success. We applied phylogenomics investigate variation L . isolates obtained Australia America. Our approach...

10.1111/1462-2920.16103 article EN Environmental Microbiology 2022-06-29

Most organisms belonging to the Saccharomycotina subphylum have high genetic diversity and a vast repertoire of metabolisms lifestyles, which explains its ecological versatility. The yeast Lachancea cidri is an ideal model for exploring interplay between genetics, function evolution. L. species that diverged from Saccharomyces lineage before whole-genome duplication exhibits broad distribution across South Hemisphere, thus displaying important success. Here, we applied phylogenomics...

10.22541/au.164182824.45750907/v1 preprint EN Authorea (Authorea) 2022-01-10

ABSTRACT Species delineation in microorganisms is challenging due to the limited markers available for accurate species assignment. Here, we applied an integrative taxonomy approach, combining extensive sampling, whole-genome sequence-based classification, phenotypic profiling, and assessment of interspecific reproductive isolation. Our work reveals presence a distinct Saccharomyces lineage Nothofagus forests coastal Patagonia. This lineage, designated chiloensis sp. nov., exhibits 7%...

10.1101/2024.04.29.591617 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-05-01

Abstract Evaluating domestication signatures beyond model organisms is essential for thoroughly understanding the genotype-phenotype relationship in wild and human-related environments. Structural variations (SVs) can significantly impact phenotypes playing an important role physiological adaptation of species to different niches, including during domestication. A detailed characterization fitness consequences these genomic rearrangements, however, still limited non-model systems, largely...

10.1101/2023.06.12.544598 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-06-13

ABSTRACT Although the typical genomic and phenotypic changes that characterize evolution of organisms under human domestication syndrome represent textbook examples rapid evolution, molecular processes underpin such are still poorly understood. Domesticated yeasts for brewing, where short generation times large plasticity were attained in a few generations selection, prime examples. To experimentally emulate lager yeast process, we created genetically complex (panmictic) artificial...

10.1101/2020.12.07.415240 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-12-08
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