A5052146585- IL-33, ST2, and ILC Pathways
- Immune Cell Function and Interaction
- Skin Diseases and Diabetes
- Immune cells in cancer
- Cancer and Skin Lesions
- Asthma and respiratory diseases
- Genetic and rare skin diseases.
Erasmus MC
2013-2023
Rockefeller University
2023
Codarts Rotterdam
2020
Haga Hospital
2013
Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. We investigated their role at nasal mucosa following allergen challenge with house dust mite. combined single-cell proteome and transcriptome profiling on from biopsies 30 allergic rhinitis 27 non-allergic subjects before after repeated challenge. Biopsies of patients showed infiltrating inflammatory HLA-DRhi/CD14+ CD16+ monocytes proallergic transcriptional changes in resident CD1C+/CD1A+ conventional...
A man in his 20s presented with a 10-year history of relapsing papules on the antihelix left ear. Less frequently, were found right ear as well. Sometimes lesions painful to applied pressure or when exposed cold winds.
Abstract Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. Here, we investigated their role at nasal mucosa following challenge with house dust mite. We combined single cell proteome and transcriptome profiling on from biopsy of allergic rhinitis non-allergic subjects, before after repeated allergen challenge. Nasal biopsies patients showed infiltrating inflammatory HLA-DR hi CD14 + monocytes CD16 monocytes, transcriptional changes in resident CD1C CD1A...