A5100307459- Simulation Techniques and Applications
- Wireless Signal Modulation Classification
- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Cancer Immunotherapy and Biomarkers
- Computational Drug Discovery Methods
- Ferroptosis and cancer prognosis
- Underwater Vehicles and Communication Systems
- Biomimetic flight and propulsion mechanisms
- FOXO transcription factor regulation
- Immunotherapy and Immune Responses
- Optimal Experimental Design Methods
- Mass Spectrometry Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Pharmacogenetics and Drug Metabolism
- Neural Networks and Applications
- Advanced Data Storage Technologies
- Ultrasound Imaging and Elastography
- Software Reliability and Analysis Research
- Flood Risk Assessment and Management
- Ultrasound and Hyperthermia Applications
- Scientific Computing and Data Management
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Multi-Objective Optimization Algorithms
- Reproductive biology and impacts on aquatic species
Nanjing University of Posts and Telecommunications
2023-2025
Yunnan Academy of Agricultural Sciences
2023-2025
First Affiliated Hospital of Anhui Medical University
2021-2025
Beijing Institute of Neurosurgery
2007-2025
Anhui Medical University
2021-2025
Capital Medical University
2007-2025
University of Science and Technology of China
2024
Southwest Medical University
2024
Affiliated Hospital of Southwest Medical University
2024
Wuhan University of Science and Technology
2023-2024
Lipoid proteinosis (LP), also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease (OMIM 247100) is a rare, autosomal recessive disorder typified by generalized thickening of skin, and certain viscera. Classical features include beaded eyelid papules laryngeal infiltration leading to hoarseness. Histologically, there widespread deposition hyaline (glycoprotein) material disruption/reduplication basement membrane. The aetiology LP currently unknown. Using DNA from three affected...
In this paper the possibility of using phased array generated multiple-focus patterns to reduce overall treatment time in ultrasound surgery while restraining prefocal heating was investigated. This done by comparing through computer simulation performance different possible schemes, i.e., single-focus scans, and simultaneous multiple focusing without scanning, when used "ablate" a 10/spl times/10/spl times/10 mm/sup 3/ tissue volume 100 mm deep. all cases, 41 foci were cover volume....
Starting from the theoretical mechanism of impact financial agglomeration on regional green innovation efficiency, and using panel data 30 provinces in China 2009 to 2017, this study calculates a index efficiency applying principal component analysis slacks-based measure (SBM) super-efficiency. The then constructs static dynamic spatial Durbin models two different weight matrices empirically test spillover effect efficiency. results reveal significant positive correlation between China's...
Radio Frequency Fingerprinting Identification (RFFI) leverages signal processing to extract unique characteristics from wireless signals for device identification. In recent years, deep learning (DL) has significantly advanced identification, catalyzing progress in RFFI research. This paper proposes an enhanced method manage variable-length inputs, typically problematic neural networks such as convolutional (CNNs) and multilayer perceptrons (MLPs), by treating these images solve data...
Glioblastoma (GBM) is one of the most lethal adult brain tumors with limited effective therapeutic options. Immunotherapy targeting B7-H3 (CD276) has shown promising efficacy in treatment gliomas. However, response to this varies among glioma patients due individual differences. It's necessary find an strategy improve immunotherapy for non-responders. In study, we demonstrated a strong correlation between aurora kinase A (AURKA) and CD276 expression tissue samples. Additionally, both AURKA...
Background Investigating the pivotal role of CTHRC1 in tumor microenvironment triple-negative breast cancer (TNBC). Method The RNA transcriptomic data obtained from Cancer Genome Atlas and single-cell sequencing TNBC Gene Expression Omnibus (GEO) were acquired subjected to analysis. A comprehensive investigation was conducted with a specific focus on characterizing its correlation invasive genes. Furthermore, additional analyses performed explore relationship between CTHRC1, immune cell...
Abstract Fragaria iinumae , a diploid progenitor species of octoploid strawberries, likely occupies basal position within the genus . In this study, we report near-complete genome assembly F. v2.0, totaling 241.14 Mb with contig N50 33.31 Mb. We identified 14 telomeric and 7 centromeric regions across its seven chromosomes. Compared to previous assemblies, v2.0 demonstrates substantial improvements in both continuity (gaps reduced from 29 0) annotation completeness, including 4,144 new genes...
Abstract Drug resistance is a major obstacle to the effective treatment of colorectal cancer (CRC). However, underlying mechanism remains unclear. In this study, we investigated function and TIPE3 in drug CRC. expression clinical samples CRC cell lines was detected using qPCR. CCK-8 colony formation assays were employed analyze proliferation cells. The apoptosis cells analyzed flow cytometry, autophagy western blotting, transmission electron microscopy, immunofluorescence. Moreover,...
Background The Comprehensive T Cell Vaccine Immune Monitoring Consortium (CTC-VIMC) was created to provide standardized immunogenicity monitoring services for HIV vaccine trials. ex vivo interferon-gamma (IFN-γ) ELISpot is used extensively as a primary assay assess cell-based candidates in trials infectious diseases and cancer. Two independent, GCLP-accredited central laboratories of CTC-VIMC routinely use their own standard operating procedures (SOPs) within two major networks Studies are...
To investigate the therapeutic effect of urolithin A (UA) on pediatric pneumonia and underlying mechanisms.The infantile model was constructed by intratracheal induction lipopolysaccharide (LPS) in 1-week-old C57BL/6 mice (male, 4-5 g). UA also injected intraperitoneally. Lung tissues each group were examined histological analysis. Autophagy, inflammation, oxidative stress assessed enzyme-linked--immunosorbent serologic assay immunoblot Moreover, pyrophosis endoplasmic reticulum evaluated...
Background Immunogenic cell death (ICD) is a result of immune infiltration (ICI)-mediated death, which also novel acknowledgment to regulate cellular stressor-mediated including drug therapy and radiotherapy. Methods In this study, TCGA GEO data cohorts were put into artificial intelligence (AI) identify ICD subtypes, in vitro experiments performed. Results Gene expression, prognosis, tumor immunity, sensitivity showed significance among subgroups, Besides, 14-gene-based AI model was able...
Background: Before the discovery of cuproptosis, copper-loaded nanoparticle is a wildly applied strategy for enhancing tumor-cell-killing effect chemotherapy. Although copper(ii)-related researches are wide, details cuproptosis-related bioprocess in pan-cancer not clear yet now, especially prognosis and drug sensitivity prediction now. Methods: In this study, VOSviewer used literature review, R4.2.0 data analysis. Public collected from TCGA GEO, local breast cancer cohort to verify...
Road crack and damage detection (RoadCDD) has been received strong attention for maintaining intelligent transportation safety. Computer vision techniques based on deep learning have proven to be very effective in detecting pavement defects related parameter information. In this paper, we propose a lightweight road method using You Only Look Once v5s (Yolov5s) framework. First, build real dataset of RoadCAVS, which contains 15,612 images with 18,709 labels, 12 kinds or rational assets. Then,...
Objective Thoracic aortic aneurysm and dissection (TAAD) is a cardiovascular disease with high mortality rate. Aging an important risk factor for TAAD. This study explored the relationship between aging TAAD investigated underlying mechanisms, which may contribute to diagnosis treatment of Methods Human genes were obtained from Atlas official website. Various datasets downloaded GEO database:the human dataset GSE52093 used screening differentially expressed (DEGs); GSE137869, GSE102397...
Most sensors for structural testing and health monitoring are “point” which strongly limit the ability to correct damage detection assessment. In this paper, long-gauge FBG sensor can sense whole area within gauge length is introduced. Bridge assessment with microstrain distribution acquired by distributed also studied. Experiments were conducted application a real prestressed box bridge was implemented. Static dynamic results show that long-gage sensing technique obtain not only global...
Simulation models are integral to modern scientific research, national defense, industry and manufacturing, in public policy debates. These tend be extremely complex, often with thousands of factors many sources uncertainty. To understand the impact these their interactions on model outcomes requires efficient, high-dimensional design experiments. Unfortunately, all too often, large-scale simulation continue explored ad hoc ways. This suggests that more researchers practitioners need aware...
Abstract Background: Intensive phototherapy (IPT) and exchange transfusion (ET) are the main treatments for extreme hyperbilirubinemia. However, there is no reliable evidence on determining thresholds these treatments. This multicenter study compared effectiveness complications of IPT ET in treatment Methods: retrospective cohort was conducted seven centers from January 2015 to 2018. Patients with hyperbilirubinemia that met criteria were included. divided into three subgroups (low-,...
A formal and general thermal dose optimisation method is developed tested. Prior methods require brute force searches wherein the temperature distributions must be computed at each iteration by solving bioheat transfer equation (BHTE) numerically. This extremely time-consuming can only used to compare a few prespecified strategies instead of obtaining more optimal result. With here, distribution calculated without BHTE done in matter minutes compared with many hours. Moreover, optimization...