Wen-Chin Chiu

ORCID: 0009-0003-4526-6478
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About
Contact & Profiles
Research Areas
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • AI in cancer detection
  • Bacterial biofilms and quorum sensing
  • Drug Transport and Resistance Mechanisms
  • Digital Imaging for Blood Diseases
  • Vibrio bacteria research studies
  • Aquaculture disease management and microbiota
  • Curcumin's Biomedical Applications
  • Cell Image Analysis Techniques
  • RNA Interference and Gene Delivery

I-Shou University
2023-2024

Vibrio parahaemolyticus is a marine bacterium that can infect and cause the death of aquatic organisms. V . also human foodborne infection via contaminated seafood, with clinical syndromes which include diarrhea, abdominal cramps, nausea so on. Since controlling important for aquaculture health, various strategies have been explored. This study investigates application antagonistic microorganisms to inhibit growth We screened environment samples identified Bacillus subtilis strain O-741...

10.1371/journal.pone.0299015 article EN cc-by PLoS ONE 2024-04-04

Drug efflux transporters, especially those belonging to the ATP-binding cassette (ABC) transporter superfamily, play a crucial role in various drug resistance issues, including multidrug (MDR) cancer and treatment-resistant depression (TRD) individuals with major depressive disorder. Key transporters this context include P-glycoprotein (P-gp), protein 1 (MRP1), breast (BCRP). This study aimed investigate modulatory effects of polyoxyethylene (20) sorbitan monolaurate (Tween 20) on these...

10.1080/1061186x.2024.2429006 article EN Journal of drug targeting 2024-11-12

Although the combination of chemotherapy and radiotherapy has increased survival rate patients with nasopharyngeal carcinoma (NPC), certain do not respond well to treatment have a poor prognosis. Therefore, novel therapeutic drugs strategies improve prognosis NPC are required. As plant extracts can suppress viability cancer cells, present study investigated whether oligonol, polyphenolic compound primarily found in lychee fruit, exerts anticancer activities cells. MTT, ELISA immunoblotting...

10.3892/br.2024.1831 article EN Biomedical Reports 2024-08-05

Abstract Endothelial cells of the aorta are an excellent model system for studying inflammatory responses, angiogenesis, atherosclerosis, blood clotting, vascular contraction, and vasodilation. Cell counting is necessary when culturing human aortic endothelial (HAECs) in order to determine cell concentration quantity, as well assess viability proliferation. Here, a machine learning-based image recognition was developed create counter. The system’s hardware includes digital microscope,...

10.1088/1742-6596/2631/1/012023 article EN Journal of Physics Conference Series 2023-11-01
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