A5074733824- CRISPR and Genetic Engineering
- Nanoplatforms for cancer theranostics
- RNA and protein synthesis mechanisms
- Marine Sponges and Natural Products
- Microbial Metabolic Engineering and Bioproduction
- Microbial Natural Products and Biosynthesis
- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- Luminescence and Fluorescent Materials
- Financial Markets and Investment Strategies
- Covalent Organic Framework Applications
- Animal Nutrition and Physiology
- Viral Infectious Diseases and Gene Expression in Insects
- Complex Network Analysis Techniques
- Protein purification and stability
- Synthesis of Indole Derivatives
- Lanthanide and Transition Metal Complexes
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Complex Systems and Time Series Analysis
- Cancer-related molecular mechanisms research
- Advanced Nanomaterials in Catalysis
- Metal-Organic Frameworks: Synthesis and Applications
- RNA Research and Splicing
- Luminescence Properties of Advanced Materials
Beijing Institute of Technology
2022-2025
Chinese Academy of Sciences
2023-2025
Xidian University
2024
Microbiology Institute of Shaanxi
2023
Institute of Microbiology
2023
Xi'an University of Technology
2023
East China University of Science and Technology
2020
South China Agricultural University
2015-2016
The pore apertures dictate the guest accessibilities of pores, imparting diverse functions to porous materials. It is highly desired construct crystalline polymers with predesignable and uniform mesopores that can allow large organic, inorganic, biological molecules enter. However, due ease formation interpenetrated and/or fragile structures, largest aperture reported in metal-organic frameworks 8.5 nm, value for covalent organic (COFs) only 5.8 nm. Herein, we a series COFs record values...
How to develop antitumor nanodrugs with low toxicity and a good curative effect is an urgent problem in the current biomedicine field. In this work, different proposed composites were simulated by finite difference time domain (FDTD) COMSOL, including material element, refractive index, particle size, shape. Also, machine learning algorithms are utilized predict absorbance at near-infrared laser of 980 nm materials. Through train, validation, test, prediction as-synthesized Pt–Mn has high...
Thermophilic cell factories have remarkably broad potential for industrial applications, but are limited by a lack of genetic manipulation tools and recalcitrance to transformation. Here, we identify thermophilic type I-B CRISPR-Cas system from Parageobacillus thermoglucosidasius find it displays highly efficient transcriptional repression or DNA cleavage activity that can be switched adjusting crRNA length less than greater 26 bp, respectively, without ablating Cas3 nuclease. We then...
is emerging as a highly promising thermophilic organism for metabolic engineering. The utilization of CRISPR-Cas technologies has facilitated programmable genetic manipulation in
A series of new antimicrobial dibenzospiroketals epicospirocins, and their biosynthetic pathway, were investigated <italic>via</italic> molecular networking from phytopathogenic fungi EN09116 for the first time.
Runting and stunting syndrome (RSS), which is characterized by lower body weight, widely occurs in broilers. Some RSS chickens simply exhibit slow growth without pathological changes. An increasing number of studies indicate that broiler strains differ susceptibility to infectious diseases, most likely due their genetic differences. The objective this study was detect the differentially expressed miRNAs mRNAs normal chickens. By integrating miRNA with mRNA expression profiling, potential...
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Abstract This paper explores the influence of fund managers’ social networks on herding behavior securities investment funds (SIFs) in China. Using data Chinese SIFs recent years as a sample, it adopts CSAD model to measure SIFs’ behavior. Combining indicators such network centrality, constraint, and size, constructs regression conducts an empirical study. The heterogeneity this is investigated four dimensions, degree behavior, gender, diploma, region. results show that: (i) larger size...
High-throughput sequencing has identified a large number of sense-antisense transcriptional pairs, which indicates that these genes were transcribed from both directions. Recent reports have demonstrated many antisense RNAs, especially lncRNA (long non-coding RNA), can interact with the sense RNA by forming an duplex. Many methods, such as RNA-sequencing, Northern blotting, RNase protection assays and strand-specific PCR, be used to detect transcript gene orientation. However, applications...