A5100722164- Cancer-related molecular mechanisms research
- Cervical Cancer and HPV Research
- Cardiac Arrest and Resuscitation
- Head and Neck Cancer Studies
- interferon and immune responses
- Ultrasound in Clinical Applications
- Genital Health and Disease
- Immune Response and Inflammation
- Respiratory Support and Mechanisms
- Hepatitis B Virus Studies
- Immune Cell Function and Interaction
Act Health
2024
Australian National University
2024
Hai phong University Of Medicine and Pharmacy
2021
Hai Phong University
2021
Kanazawa University
2016-2018
Abstract Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and etiologically linked to several cancers, including cervical genital cancers. NKG2D, an activating receptor expressed by NK cells, plays important role in cancer immune-surveillance. We analyzed impact of a NKG2D gene variant, rs1049174, on incidence HPV-related cancers Vietnamese patients utilized various molecular approaches elucidate mechanisms regulation rs1049174. In group 123 with HPV+...
Oropharyngeal squamous cell carcinoma (OPSCC), a subset of head and neck (HNSCC), involves the palatine tonsils, soft palate, base tongue, uvula, with ability to spread adjacent subsites. Personalized treatment strategies for Human Papillomavirus-associated oropharynx (HPV+OPSCC) are yet be established. In this article, we summarise our current understanding pathogenesis HPV+OPSCC, intrinsic role immune system, ICI clinical trials, potential small molecule immunotherapy in HPV+OPSCC.
We previously reported human papillomavirus type 52 (HPV52) as the most prevalent high-risk genotype in non-cancer individuals Vietnam. This study aimed to evaluate HPV genotypes and HPV16 E6 E7 (E6/E7) gene variations Vietnamese patients with genital cancers. Biopsy samples were collected from 124 cancers (20 vaginal, 50 vulvar, 54 penile cancer). The HPV-DNA was amplified genotyped, E6/E7 genes compared those for women normal cervical cytology (N = 23). detected 80.6% (100/124) of cancer...