A5072757526- Computational Drug Discovery Methods
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- HER2/EGFR in Cancer Research
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac electrophysiology and arrhythmias
- Biosimilars and Bioanalytical Methods
- Protein Degradation and Inhibitors
- Cerebral Palsy and Movement Disorders
- Bioinformatics and Genomic Networks
- Click Chemistry and Applications
- CAR-T cell therapy research
- Complementary and Alternative Medicine Studies
- Cell Image Analysis Techniques
National Cancer Institute
2023
Frederick National Laboratory for Cancer Research
2023
Abstract The NCI-60 human tumor cell line panel has proved to be a useful tool for the global cancer research community in search novel chemotherapeutics. publicly available characterization and compound screening data from assay have significantly contributed understanding of cellular mechanisms targeted by new oncology agents. Signature sensitivity/resistance patterns generated given chemotherapeutic agent against long served as fingerprint presentations that encompass target information...
<p>Analytical Data</p>
<p>Analytical Data</p>
<p>Figures S1 and S2</p>
<p>Table of GI50 data</p>
<div>Abstract<p>The NCI-60 human tumor cell line panel has proved to be a useful tool for the global cancer research community in search novel chemotherapeutics. The publicly available cell-line characterization and compound screening data from assay have significantly contributed understanding of cellular mechanisms targeted by new oncology agents. Signature sensitivi-ty/resistance patterns generated given chemotherapeutic agent against long served as fingerprint presentations...
<p>Table of GI50 data</p>
<p>Figures S1 and S2</p>
Abstract The NCI60 human tumor cell line panel is a useful tool in the discovery and development of new anticancer agents. publicly available cell-line characterization compound screening data from screen have contributed to identifying cellular mechanisms potential Mean-graph sensitivity/resistance patterns serve as fingerprint for molecular target identification mechanism action (MOA). A resource was developed based on 175 FDA-approved oncology drugs (AOD) plus &gt;825 investigational...
<div>Abstract<p>The NCI-60 human tumor cell line panel has proved to be a useful tool for the global cancer research community in search novel chemotherapeutics. The publicly available characterization and compound screening data from assay have significantly contributed understanding of cellular mechanisms targeted by new oncology agents. Signature sensitivity/resistance patterns generated given chemotherapeutic agent against long served as fingerprint presentations that...
<div>Abstract<p>The NCI-60 human tumor cell line panel has proved to be a useful tool for the global cancer research community in search novel chemotherapeutics. The publicly available cell-line characterization and compound screening data from assay have significantly contributed understanding of cellular mechanisms targeted by new oncology agents. Signature sensitivi-ty/resistance patterns generated given chemotherapeutic agent against long served as fingerprint presentations...
<p>Figures S1 and S2</p>
<p>Analytical Data</p>
<p>Figures S1 and S2</p>
<p>Table of GI50 data</p>
<p>Table of GI50 data</p>
<p>Analytical Data</p>