- Multiple Sclerosis Research Studies
- SARS-CoV-2 and COVID-19 Research
- Rheumatoid Arthritis Research and Therapies
- Polyomavirus and related diseases
- Systemic Lupus Erythematosus Research
- Peripheral Neuropathies and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Research on Leishmaniasis Studies
- Alcoholism and Thiamine Deficiency
- Acute Lymphoblastic Leukemia research
- Stroke Rehabilitation and Recovery
- Viral Infections and Immunology Research
- Pharmaceutical Practices and Patient Outcomes
- Metabolism and Genetic Disorders
- Prion Diseases and Protein Misfolding
- Cerebrovascular and genetic disorders
- Moyamoya disease diagnosis and treatment
- Hair Growth and Disorders
- Melanoma and MAPK Pathways
- Vitamin D Research Studies
- Vitamin C and Antioxidants Research
- Chronic Myeloid Leukemia Treatments
- Biological Research and Disease Studies
- Viral-associated cancers and disorders
Sheikh Shakhbout Medical City
2020-2024
Khalifa University of Science and Technology
2023
Gulf Medical University
2021
Mafraq Hospital
2014-2020
Spectrum Health
2012
Background: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, associated with demyelination and inflammation. Relapsing forms MS (RMS) encompass all patients experiencing relapses. While there currently no cure for MS, introduction several disease-modifying therapies (DMTs) has significantly reduced risk relapse disability in MS. There a high unmet need easy-to-administer DMT that can be used early treatment pathway. Objectives: This study aimed to evaluate...
This article discusses the opinions of multiple sclerosis (MS) experts in Gulf region on use high-efficacy disease-modifying drugs (DMDs; natalizumab, fingolimod, alemtuzumab, cladribine tablets, and ocrelizumab) clinical practice. The reviewed current literature including pivotal trials meta-analyses for DMDs, supplemented by expert usage these DMDs Several criteria were discussed panel based different efficacy, safety, convenience attributes. concluded that all available treatment MS have...
Inconvenient administration and side effects of some disease-modifying therapies (DMTs) for relapsing multiple sclerosis (RMS) can deter adherence. We evaluated treatment satisfaction with cladribine tablets (CladT) RMS in the Arabian Gulf. This was a non-interventional, multicentre, prospective observational study non-pregnant/lactating adults (aged ≥ 18 years) eligible 1st CladT (EU labelling). The primary outcome overall at 6 months (Treatment Satisfaction Questionnaire Medication...
It is unknown whether neurohospitalist evaluation improves door-to-needle times (DNT) in patients with acute ischemic stroke.The purpose of this study to determine the impact on DNT for stroke receiving intravenous tissue plasminogen activator (tPA) presenting within 4.5 hours symptom onset.We retrospectively identified consecutive who received tPA between 0 and hours. We determined compared nonneurohospitalists versus neurohospitalists a 26-month period from 2009 2011. Our main outcome...
Recent research has expanded our understanding of the natural history and clinical course multiple sclerosis (MS) in Arabian Gulf region. In addition, number available therapies for MS increased greatly recent years, which complicates considerably design therapeutic regimens. We, an expert group physicians practising countries, present pragmatic consensus recommendations use disease-modifying therapy, according to level disease activity, objective criteria, prior treatment (if any) received...
The prevalence of multiple sclerosis (MS) is increasing in Gulf Cooperation Council (GCC) countries. Multiple contributes to significant burden on patients and caregivers. pharmacological treatment MS involves treating acute exacerbations preventing relapses disability progression using disease-modifying therapies. Clinical evidence suggests that teriflunomide one the therapeutic choices for with relapsing-remitting (RRMS). However, genetic cultural differences across different regions may...
Objective: Wernicke encephalopathy (WE) is a rare disorder resulting from deficiency of thiamine (vitamin B1). It precipitated by conditions including thyrotoxicosis, hyperemesis gravidarum, and alcoholism. The disease not always suspected in pediatric patients, its presentation can be atypical, so it often underdiagnosed.
Background: Hypovitaminosis D is amongst those strongly suggested risk factors for multiple sclerosis (MS). Although the association of vitamin deficiency with MS has been established in several studies recent years, there are not many to assess and compare degree status newly diagnosed patients versus control group worldwide, especially UAE. Objective: To observe state cases determine presence any significant association. Methods: In this retrospective study, 30 were randomly selected...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare genetic disorder due to NOTCH 3 mutation on chromosome 19 resulting in small vessel disease that may mimic many other neurological disorders like migraine, stroke, transient ischaemic attack (TIA), dementia psychiatric illnesses. The confirmed by testing investigations MRI skin biopsy are also helpful. Here, we present 43-year-old male CADASIL through testing, who was initially...