A5047040720- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- SARS-CoV-2 and COVID-19 Research
- Rheumatoid Arthritis Research and Therapies
- Acute Lymphoblastic Leukemia research
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- Ocular Diseases and Behçet’s Syndrome
- Immunotherapy and Immune Responses
- Research on Leishmaniasis Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Autoimmune and Inflammatory Disorders Research
- Viral Infections and Immunology Research
- Hereditary Neurological Disorders
- CNS Lymphoma Diagnosis and Treatment
- Autoimmune Neurological Disorders and Treatments
- Global Health Workforce Issues
- Mesenchymal stem cell research
- Garlic and Onion Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pregnancy and Medication Impact
- Phagocytosis and Immune Regulation
- Sarcoidosis and Beryllium Toxicity Research
- Monoclonal and Polyclonal Antibodies Research
King Saud bin Abdulaziz University for Health Sciences
2019-2025
King Abdullah International Medical Research Center
2020-2025
National Guard Health Affairs
2019-2025
King Abdulaziz Medical City
2019-2024
Oakland University
2021
King Fahad Specialist Hospital
2020
University of Calgary
2012
Abstract Background In 2015, the first nationwide, multicenter Multiple Sclerosis (MS) registry was initiated in Kingdom of Saudi Arabia (KSA) mainly with an objective to describe current epidemiology, disease patterns, and clinical characteristics MS Arabia. This article aimed report initial findings regional prevalence MS. Method a national launched KSA register all patient confirmed diagnosis according 2010 McDonald Criteria. The identify recruit healthcare facilities treating patients...
Abstract Background In the phase 2 CAMMS223 trial (NCT00050778), alemtuzumab significantly improved clinical and MRI outcomes versus subcutaneous interferon beta-1a over 3 years in treatment-naive patients with relapsing–remitting MS. Here, we assess efficacy safety of 12 who enrolled CAMMS03409 extension (NCT00930553), available follow-up through subsequent TOPAZ (NCT02255656). Methods CAMMS223, received courses (12 mg/day; baseline: 5 days; months later: days); 22% a third course....
The emergence of high-efficacy disease-modifying therapies (HE DMT) for multiple sclerosis (MS) may pose challenges to the administration and monitoring burden therapies. This article presents results Delphi consensus method generate insights from experts on HE DMT in Saudi Arabia with a special focus cladribine. Between January March 2023, two-round modified was used establish regarding DMTs MS. Through questionnaire, advisors evaluated 17 properties six individual basis their clinical...
To investigate whether Persons with MS (pwMS) in Saudi Arabia want to discuss their long-term prognosis (LTP) and the factors influencing this decision using a self-administered online questionnaire. In cross-sectional study, an questionnaire was distributed from December 2022 July 2023 across determine pwMS interest discussing LTP. Participants included patients over 18 years, of any gender, diagnosed MS. A nonprobability convenience sampling technique used, questionnaires sent through...
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic, progressive neurodegeneration of the central nervous system (CNS), and it most common inflammatory neurological affecting young adults. Given nature disease, psychiatric disorders are more prevalent among these patients, as reported in literature; however, data Saudi Arabia limited. This study aimed to estimate prevalence major depression generalized anxiety disorder patients with MS their association different...
Background Multiple Sclerosis (MS) is a chronic CNS inflammatory disease commonly affecting young adults. Both genetics and environmental factors have been reported to role in pathophysiology of the disease. Objective This article aims report familial nature aspects MS Saudi Arabia. Method The study utilized data collected by National Registry between 2015 2018; especially relevant history MS. SPSS 22 was used for all analysis reporting. Statistical significance set at p-value < 0.05....
Introduction: Brucellosis is a zoonotic disease that can affect the central and peripheral nervous system it has variable neurological manifestation. However, brucellosis infection presents with acute neuropathy mimicking Guillain-Barre syndrome (GBS) rarely reported in literature. Objective method: We report 56-year-old man who was initially diagnosed GBS, then he confirmed to have Brucella infection. also did systematic literature review study natural history management of previously cases...
Background Multiple sclerosis (MS) patients are no strangers to the emergency department (ED) due relapsing and progressive nature of disease associated complications. This study aimed identify patterns ED visits among diagnosed with MS, underlying causes these visits, factors visits. Methods was a single center retrospective cohort which utilized non-probability consecutive sampling technique include all MS (471 patients) from March 2016 October 2021 in King Abdulaziz Medical City, Jeddah,...
ntravascular lymphoma (IVL) is an extranodal B-cell that involves the lumina of small and medium size vessels. 1 Neurologic presentations are varied include encephalopathy, myelopathy, polyradiculoneuropathy, among other features. 1,23][4] Early diagnosis treatment before disease dissemination difficult but increases progression-free survival remission. 1We describe a patient with isolated CES subtle non-nodular MRI nerve root enhancement, who was identified to harbor IVL by cauda equina...
Multiple sclerosis (MS) is a chronic autoimmune disease that causes demyelination of the central nervous system. No treatment has been shown to be curative; thus, we assume tendency for patients with MS use unconventional therapies, such as complementary and alternative medicine (CAM), might increase. The aim this study was explore pattern CAM among at tertiary health care center in Saudi Arabia (SA). This questionnaire-based observational cross-sectional targeted adult diagnosed King...
Tacrolimus is an immunosuppressant agent utilized for solid organ transplantations. It has been associated with rare neurotoxic effects. This case highlights one possible delayed effect. A 52-year-old lady on tacrolimus (3 mg daily) among her immunosuppressive regimen kidney transplant 16 year ago. She presented unilateral left paracentral black dots progressing over a week, periorbital and temporal pain. The patient was diagnosed papillitis. tapered then changed to cyclosporine....
BackgroundThe outbreak of coronavirus disease 2019 (COVID-19) has rapidly spread and developed as a pandemic threatening global health. Patients with multiple sclerosis (MS)–an autoimmune demyelinating inflammatory the central nervous system (CNS)–are predominantly treated immunomodulatory/immunosuppressive disease-modifying therapies (DMTs), which can increase risk infection. Therefore, there is concern that these patients may have higher COVID-19. In response to growing concerns...
Patients with isolated neurosarcoidosis (NS) can present neurological symptoms that mimic other neurologic conditions, such as multiple sclerosis (MS). In this article, we a case of 25-year-old man transverse myelitis. Magnetic resonance imaging (MRI) the brain and spine showed several, periventricular, infratentorial, spinal cord white matter lesions. He was diagnosed MS started on fingolimod, which did not result in any improvement. Follow-up MRI longitudinally extensive lesion...
The prevalence of multiple sclerosis (MS) appears to be increasing worldwide. However, data on the pediatric onset MS is lacking, particularly in developing countries. This study aimed at reporting current burden five regions Saudi Arabia. used relevant from National Registry that was operational between 2015 and 2018. patients with all hospitals included registry retrospectively analyzed using age diagnosis. Patients who were 1-18 years old when diagnosed analysis. 287 MS, a mean diagnosis...