- Monoclonal and Polyclonal Antibodies Research
- Immune cells in cancer
- Systemic Lupus Erythematosus Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune Response and Inflammation
- Inflammatory Myopathies and Dermatomyositis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- T-cell and Retrovirus Studies
- Signaling Pathways in Disease
- Chronic Lymphocytic Leukemia Research
- Heterotopic Ossification and Related Conditions
- Effects of Radiation Exposure
- Rheumatoid Arthritis Research and Therapies
- Viral Infections and Immunology Research
- Neurological Disease Mechanisms and Treatments
- Multiple Sclerosis Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- Herpesvirus Infections and Treatments
- Nuclear and radioactivity studies
- Lipid metabolism and disorders
- Blood Coagulation and Thrombosis Mechanisms
- Pharmacological Effects of Natural Compounds
- Biochemical and Structural Characterization
- Peripheral Nerve Disorders
- Orthopedic Infections and Treatments
University of Manchester
2024-2025
Manchester Academic Health Science Centre
2024-2025
University College Hospital
1987
University College London
1987
Wellcome Trust
1961-1983
United States Department of Veterans Affairs
1975
University of California, Los Angeles
1974-1975
Royal National Hospital for Rheumatic Diseases
1974
London Postgraduate Medical and Dental Education
1969-1971
University of Dundee
1971
the pig by Mayer in 1825 and Bang 1876 a female patient who died of volvulus.It was reported living Hahn 1899.Since then there have been number reports, mostly single cases, but Doub Shea (1960) described 16 cases their practice.Despite those records natural history is badly docu- mented.Jones (1948) case which laparotomy had shown no cysts.Two half years later repeated showed pneumatosis colon mesentery.Griffiths (1955) 1946 cysts; colonic symptoms began one year later-for example, blood...
Inflammation is a key contributor to stroke pathogenesis and exacerbates brain damage leading poor outcome. Interleukin-1 (IL-1) an important regulator of post-stroke inflammation, blocking its actions beneficial in pre-clinical models safe the clinical setting. However, distinct roles two major IL-1 receptor type 1 agonists, IL-1α IL-1β, specific role ischemic remain largely unknown. Here we show that IL-1β have different spatio-temporal expression profiles after experimental stroke, with...
Certain drugs, originally developed for the chemo- therapy of cancer, are now also used in control autoimmune diseases man.Cyclophosphamide, a potent alkylating agent, has an established place treatment nephrotic syndrome children (Cameron, 1968) and been with some success systemic lupus erythematosus (Seah, Wong, Chew, Jayaratnam, 1966) lupus-like nephritis NZB NZW F1 hybrid mouse (Russell Hicks, 1968).More recently cyclophosphamide (Fosdick, 1968; Smyth, azathioprine (Mason, Currey,...
Abstract The biological and chemical examination of thyroid samples has demonstrated the inadequacy B.P. assay, which is based upon determination so-called “thyroxine iodine”. It suggested that, in absence specific methods for determining thyroxine tri-iodothyronine thyroid, assay should be replaced by a assay. mouse anoxia method shown to suitable this purpose. potencies assayed thus over past 3 years, together with data clinical comments are presented. relative activities constituents...
Abstract Inflammation is a key contributor to stroke pathogenesis and exacerbates brain damage leading poor outcome. Interleukin-1 (IL-1) an important regulator of post-stroke inflammation, blocking its actions beneficial in pre-clinical models safe the clinical setting. However, distinct roles two major IL-1 receptor type 1 agonists, IL-1α IL-1β, specific role ischemic remain largely unknown. Here we show that IL-1β have different spatio-temporal expression profiles after experimental...
The cells in synovial fluid from patients with rheumatoid arthritis contain a small percentage of macrophages. Such macrophages were isolated and cultured alone homologous heterologous lymphocytes for 24 hours, an attempt to identify possible contact between living was found, clustering around macrophages, particularly well shown by scanning electron microscopy.