Hanfei Deng

ORCID: 0009-0003-7070-461X
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About
Contact & Profiles
Research Areas
  • Neural dynamics and brain function
  • Neural and Behavioral Psychology Studies
  • Memory and Neural Mechanisms
  • Radiation Therapy and Dosimetry
  • Human-Automation Interaction and Safety
  • Neuroscience and Neuropharmacology Research
  • Radiation Effects and Dosimetry
  • Tactile and Sensory Interactions
  • Advanced Radiotherapy Techniques
  • Medical Imaging Techniques and Applications
  • Autism Spectrum Disorder Research
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neural Engineering
  • Neuroendocrine regulation and behavior
  • Psychosomatic Disorders and Their Treatments
  • Neuroscience of respiration and sleep
  • Neurological disorders and treatments
  • Receptor Mechanisms and Signaling
  • Ergonomics and Musculoskeletal Disorders
  • Multisensory perception and integration
  • Action Observation and Synchronization
  • Photoreceptor and optogenetics research

Beihang University
2025

Fudan University
2024

State Key Laboratory of Medical Neurobiology
2024

Cold Spring Harbor Laboratory
2020-2021

Shanghai Institutes for Biological Sciences
2016-2017

Chinese Academy of Sciences
2016-2017

Center for Excellence in Brain Science and Intelligence Technology
2016

University of Chinese Academy of Sciences
2016

Johns Hopkins Medicine
2006

Johns Hopkins University
2006

Defense is a basic survival mechanism when animals face danger. Previous studies have suggested that the midbrain periaqueductal gray (PAG) essential for generation of defensive reactions. Here we showed optogenetic activation neurons in PAG mice was sufficient to induce series responses (including running, freezing, and avoidance). However, endogenous neural dynamics underlying behaviors still remain elusive. Using chronic extracellular recording, recorded spiking activities freely behaving...

10.1523/jneurosci.4425-15.2016 article EN Journal of Neuroscience 2016-07-20

Abstract The anterior cingulate cortex (ACC) has long been thought to regulate conflict between an object of attention and distractors during goal-directed sustained attention. However, it is unclear whether ACC serves itself. Here, we developed a task in which the time course could be controlled rats. Then, using pharmacological lesion experiments, employed assess function We then recorded neuronal activity multichannel extracellular recording techniques identified specific neurons...

10.1038/srep43101 article EN cc-by Scientific Reports 2017-02-23

Abstract Working memory (WM) research has primarily focused on visual and verbal information, while relatively little is known about tactile information. This study aims to explore the capacity of vibrotactile WM (vtWM) using frequency sequencing task, focuses its functions in simultaneous maintenance transformation supervision, coordination. We conducted four experiments: Experiments 1 2 used simple 3 4 added additional processing tasks (a task a task) task. demonstrated 3‐unit during vtWM...

10.1111/nyas.15327 article EN Annals of the New York Academy of Sciences 2025-04-04

The willingness to wait for delayed reward and information is of fundamental importance deliberative behaviors. orbitofrontal cortex (OFC) thought be a core component the neural circuitry underlying capacity control waiting. However, correlates active waiting causal role OFC in still remain largely unknown. Here, we trained rats perform task (waiting pseudorandom time obtain water reward), recorded neuronal ensembles throughout task. We observed that subset neurons exhibited ramping...

10.1111/ejn.13320 article EN European Journal of Neuroscience 2016-06-23

Purpose: A small animal radiation platform equipped with on-board conebeam CT and conformal irradiation capabilities is being constructed for translational research. This work reports on the dosimetric characteristics of x-ray lens subsystem used high-resolution dose delivery. Method Materials: constant voltage 225 kVp beam from a 0.4 mm focal spot shaped directed to enter 1.5 cm long, 2 diameter cylindrical multi-layer graphite placed 16 downstream source. The emits converging circular...

10.1118/1.2241748 article EN Medical Physics 2006-06-01

ABSTRACT The salience assignment is pivotal for both natural and artificial intelligence. Pioneering studies established that basal forebrain cholinergic neurons process behaviorally relevant salient information. However, the neural circuit mechanism underlying remains poorly understood. Here we show acetylcholine (ACh) level in basolateral amygdala (BLA) dynamically represented behavioral salience. Distinct neuronal subpopulations nucleus accumbens (NAc), D1- D2-expressing medium spiny...

10.1101/2024.07.30.605919 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-07-31
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