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Elena Guido Vinzoni

ORCID: 0009-0003-7163-1360
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About
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A5091946256
Research Areas
  • Cancer Cells and Metastasis
  • Phagocytosis and Immune Regulation
  • Pancreatic function and diabetes
  • 3D Printing in Biomedical Research
  • Cancer Genomics and Diagnostics

ETH Zurich
 2023-2024

 In vivo interaction screening reveals liver-derived constraints to metastasis
OPENALEX - Publications 
Costanza Borrelli Morgan Roberts Davide Eletto Marie‐Didiée Hussherr Hassan Fazilaty and 16 more Tomáš Valenta Atefeh Lafzi Jonas A. Kretz Elena Guido Vinzoni Andromachi Karakatsani Srivathsan Adivarahan Ardian Mannhart S Kimura Ab Meijs Farah Mhamedi İlhan E. Acar Kristina Handler Xenia Ficht Randall J. Platt Salvatore Piscuoglio Andreas E. Moor

It is estimated that only 0.02% of disseminated tumour cells are able to seed overt metastases

10.1038/s41586-024-07715-3 article EN cc-by Nature 2024-07-24
 In vivo screening of tumor-hepatocyte interactions identifies Plexin B2 as a gatekeeper of liver metastasis
OPENALEX - Publications 
Costanza Borrelli Morgan E. Roberts Davide Eletto Atefeh Lafzi Jonas A. Kretz and 9 more Hassan Fazilaty Marie‐Didiée Hussherr Elena Guido Vinzoni Kristina Handler Jan Michler Srivathsan Adivarahan Salvatore Piscuoglio Xenia Ficht Andreas E. Moor

Abstract It is estimated that only 0.02% of disseminated tumor cells are able to seed overt metastases 1 . While this indicates the presence environmental constraints metastatic seeding, landscape host factors controlling process remains largely unknown. Combining transposon technology 2 and fluorescent niche labeling 3 , we developed an in vivo CRISPR activation screen systematically investigate influence hepatocytes on seeding liver. Our approach enabled identification Plexin B2 as a...

10.1101/2023.05.15.540681 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-05-15
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