A5114374749- Molecular Biology Techniques and Applications
- Advanced Biosensing Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Asthma and respiratory diseases
- Forensic and Genetic Research
- Dermatology and Skin Diseases
- Animal Genetics and Reproduction
- Genetic Mapping and Diversity in Plants and Animals
- Connexins and lens biology
- Epigenetics and DNA Methylation
- Prenatal Screening and Diagnostics
- Dental materials and restorations
- CRISPR and Genetic Engineering
- Neurogenetic and Muscular Disorders Research
- DNA Repair Mechanisms
- Ion channel regulation and function
- Biosensors and Analytical Detection
- Congenital limb and hand anomalies
- Tendon Structure and Treatment
- Allergic Rhinitis and Sensitization
- Endodontics and Root Canal Treatments
- Muscle Physiology and Disorders
- Genetic Syndromes and Imprinting
- Intraocular Surgery and Lenses
- Metabolism and Genetic Disorders
Austrian Institute of Technology
2017-2020
Heidelberg University
2001-2010
Justus-Liebig-Universität Gießen
2003-2008
Charité - Universitätsmedizin Berlin
2000-2007
Max Delbrück Center
1996-2001
Guru Nanak Dev University
2001
University Hospital Heidelberg
2001
Ingenium (Germany)
2000
Humboldt-Universität zu Berlin
2000
Phenex Pharmaceuticals (Germany)
2000
The triple A or Allgrove's syndrome (MIM*231550) is an autosomal recessive disease characterized by the triad of adrenocorticotropic hormone (ACTH) resistant adrenal insufficiency, achalasia and alacrima. Since its first description Allgrove et al. (1978) more than 70 cases from all over world have been reported. manifests itself during decade life with severe hypoglycaemic episodes which can cause sudden death. frequent association neurological disorders presenting as a mixed pattern upper...
Malignant hyperthermia (MH) is an autosomal dominant disorder which potentially lethal in susceptible individuals on exposure to commonly used inhalational anaesthetics and depolarising muscle relaxants. Crises reflect the consequences of disturbed skeletal calcium homeostasis. Susceptibility was first localised chromosome 19q13.1 ryanodine receptor, RYR1 (the release channel sarcoplasmic reticulum). Defects this gene have been identified cosegregate with MHS phenotype evidence as their...
Growth and differentiation factor-5 (GDF-5) is essential for normal skeletal development induces tendon-and ligament-like structures at ectopic sites. Therefore, we investigated the influence of a GDF-5-coated suture on healing Achilles tendon in rats. The right 80 rats was transected sutured with an absorbable polyglactin suture. Animals were randomized to uncoated-suture control group. At 1, 2, 4 8 weeks after surgery repair tissue evaluated biomechanically histologically. Biomechanical...
Cardiovascular diseases (CVDs) are the most common cause of mortality worldwide. In acute cardiovascular conditions, time is a crucial player in outcomes disease management. Given ease and noninvasiveness obtaining saliva, salivary biomarkers may provide rapid efficient diagnosis CVD. Here, we reviewed published data on value molecules for CVD, especially care settings. this review, show that some such as creatinine kinase myocardial band, C‐reactive protein, troponin‐1, myoglobin exhibited...
Abstract Iodine deficiency is the most important etiological factor for euthyroid endemic goiter. However, family and twin pair studies also indicate a genetic predisposition simple In hypothyroid goiters several molecular defects in thyroglobulin (TG), thyroperoxidase (TPO), Na+/I− symporter (NIS) genes have been identified. The TSH receptor with its central role thyroid function growth strong candidate gene. Therefore, we investigated proposita relapsing goiter her family, which members...
To facilitate whole-genome scan experiments, we selected a panel of 128 microsatellite markers on the basis spacing and polymorphism in strains DBA/2, BALB/c, AKR, C57BL/6, C57BL/10, A/J, C3H, 129/J, SJL/J, JF1, PWB. Many primer pairs were redesigned for better performance. The last four not characterized previously using these markers. JF1 PWB are particularly interesting intersubspecific crosses offering high polymorphism. We provide allele size data add them to emerging radiation hybrid...