A5113858656- Erythrocyte Function and Pathophysiology
- Pancreatic function and diabetes
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Malaria Research and Control
- Neonatal Health and Biochemistry
- NMR spectroscopy and applications
- Hydrocarbon exploration and reservoir analysis
- Lipid Membrane Structure and Behavior
- Ion Transport and Channel Regulation
- Cancer Immunotherapy and Biomarkers
- Hydraulic Fracturing and Reservoir Analysis
- vaccines and immunoinformatics approaches
- Hemoglobinopathies and Related Disorders
- Mosquito-borne diseases and control
- Mass Spectrometry Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Chemical Reaction Mechanisms
- Social Sciences and Policies
- Protein Structure and Dynamics
- Geophysical and Geoelectrical Methods
- Mediterranean and Iberian flora and fauna
- Corneal Surgery and Treatments
Escuela Politécnica del Ejército
2024-2025
Weatherford (Norway)
2022
Universidad Centroccidental Lisandro Alvarado
2019
Universidad Independiente
2019
Central University of Venezuela
1995-2017
Tecnológico de Monterrey
2015
Universidad San Francisco de Quito
2015
Baker Hughes (United States)
2007
Ludwig Cancer Research
1994-2000
Sociedade Brasileira de Biologia Celular
1995
1. A study has been made of the relationship between concentration internal calcium and permeability human red cell membranes to sodium potassium.2. Fresh cells contain very little calcium, but after being depleted ATP by ageing they took up from Ringer solution. The entry was unaffected external potassium markedly pH dependent. When supplied with energy, calcium-loaded actively extruded a saturable process which also distribution across membranes. activity pump sufficient maintain low found...
A synthetic peptide, (DPPPPNPN)2D, representing a subunit of the repeat domain Plasmodium berghei circumsporozoite protein, was conjugated to tetanus toxoid using bisdiazobenzidine. Immunization mice and rats with conjugate induced high serum titers antibodies parasite, most animals were completely protected from malaria infection when challenged sporozoites.
El suelo es un ecosistema vital para la supervivencia de toda especie dentro del planeta. Este recurso está en riesgo debido a procesos erosivos ocasionados por factores naturales y potenciados actividades antropológicas. presente estudio evaluó calidad los terrenos afectados no incendios forestales Comuna Centro Pueblo Alangasí. Se evaluaron cinco parcelas (197, 200, 205, 274 B) través pruebas cualitativas (cromatografía Pfaiffer) cuantitativas (método gravimétrico LOI). caracterizó...
Abstract This report shows that lymphoid tissues of mice which have resolved a primary infection with Leishmania major contain parasite‐specific histocompatibility complex (MHC) class I‐restricted cytolytic CD8 + T cell precusors can be expanded after specific restimulation in vitro syngeneic antigen‐presenting cells pulsed cyanogen bromide digest L. . In H‐2 b mice, two distinct populations were identified both lysed target ‐derived peptides but restricted by different I gene product....
CD8(+) cytolytic T lymphocytes (CTL) play a fundamental role in the clearance of malaria parasites from liver mouse models. In humans, however, only low levels parasite-specific have been observed individuals living endemic areas. present study, we identified high circulating specific for previously described HLA-A2-restricted CTL epitope circumsporozoite (CS) protein Plasmodium falciparum an adult Burkina Faso, as evidenced by IFN-gamma ELISPOT assay and MHC-tetramer technology. After...
The observed equilibrium constants for hydrolysis (Kobs) of a phosphoester and phosphoanhydride bond were measured under variety conditions likely to alter the interactions reactants products with water. These included increasing pH medium from 5.0 10.0, MgCl2 concentration form 0 200 mM, decreasing water activity by adding either dimethyl sulfoxide (50%, v/v) or polyethylene glycol 6,000-8,000 w/v). Kobs phosphoesters such as phosphoserine, glucose phosphate, glycerol ethylene phosphate...
Abstract We have previously demonstrated that it is possible to induce a consistent and strong cytolytic T lymphocyte (CTL) response synthetic peptides, corresponding poorly immunogenic malaria CTL epitopes, by co‐injecting them with peptides representing defined helper (Th) epitopes in incomplete Freund's adjuvant (IFA). In this study we tested different immunization protocols improve further the elicitation of response. show mixture Th + administered IFA was enhanced previous injection...
Despite previous reports [McLaughlin (1985) Mol. Biochem. Parasitol. 15, 189-201; Ghosh, Ray, Sarkar and Bhaduri (1990) J. Biol. Chem. 265, 11345-11351; Mazumder, Mukherjee, Ray (1992) 267, 18440-18446] suggesting that the plasma-membrane Ca(2+)-ATPases of different trypanosomatids differ from Ca2+ pumps present in mammalian cells, Trypanosoma cruzi Ca(2+)-ATPase shares several characteristics with other systems. This enzyme could be partially purified epimastigote vesicles using...