A5003299466- Aluminum toxicity and tolerance in plants and animals
- Alzheimer's disease research and treatments
- MicroRNA in disease regulation
- Medicinal Plants and Neuroprotection
- Autophagy in Disease and Therapy
- Gut microbiota and health
- Neurogenesis and neuroplasticity mechanisms
- Natural Products and Biological Research
- Cardiac Ischemia and Reperfusion
- Peroxisome Proliferator-Activated Receptors
- Acupuncture Treatment Research Studies
- Cancer-related molecular mechanisms research
- Neuroscience and Neuropharmacology Research
- Natural Antidiabetic Agents Studies
- Vagus Nerve Stimulation Research
Xinxiang Medical University
2024
Wenzhou Medical University
2024
Zhejiang Lab
2024
Shenyang Medical College
2022-2023
Dysbiosis of gut microbiota (GM) is intricately linked with cognitive impairment and the incidence traumatic brain injury (TBI) in both animal models human subjects. However, there limited understanding impact mechanisms fecal transplantation (FMT) on barrier function treatment TBI induced by gas explosion (GE). We have employed FMT technology to establish dysbiosis male rats, subsequently conducted non-targeted metabolomics diversity analysis explore bacteria potential functional roles....
Cognitive impairment (CI) causes severe of brain function and quality life patients, which brings a great burden to society. Cerebral hypoxia is an important factor in the pathogenesis CI. Hyperbaric oxygen (HBO) therapy may mitigate hypoxia-induced CI, but its efficacy mechanisms are not fully understood. In this study, mice model CI induced by environment was established, then behavioral tests, pathological examination, metabolomic lipidomic analyses, molecular biology were used assess...
The present investigation aimed to analyze the in vivo study support with silico molecular docking mechanism of natural phenolic compounds Syringic acid (SA), Resveratrol (RV), Gallic (GA) and combination (COMB) SA + RV against Isoproterenol (ISO) myocardial necrotic rats. Methods: were tested for lipid metabolism enzymes HMG-CoA reductase lipoprotein lipase (LPL) regulatory activities. Rats orally pretreated 50 mg/ kg each SA, RV, GA COMB (SA 25 kg) 30 days. has taken as positive control....
Abstract Aluminum (Al) is a neurotoxin that gradually accumulates in the brain human life, resulting oxidative injury related to Alzheimer's disease (AD) and other diseases. In this study, learning memory of rats exposed different aluminum concentrations ( 0.0 g/L, 2.0 4.0 g/L 8.0 g/L) were studied, observed by shuttle box experiment. With HE staining, Western Blot, Immunofluorescence, RT-PCR, morphology nerve cells hippocampus rat observed, levels activator protein-1 (AP-1) gene protein,...