A5023093346- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer Genomics and Diagnostics
- Nutritional Studies and Diet
- Pancreatic function and diabetes
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Amyotrophic Lateral Sclerosis Research
- Phytoestrogen effects and research
- Pharmacological Effects of Natural Compounds
- Diet, Metabolism, and Disease
- Traditional Chinese Medicine Analysis
- Fuel Cells and Related Materials
- Diabetes Treatment and Management
- Sodium Intake and Health
- Liver Disease Diagnosis and Treatment
- RNA Research and Splicing
- Diabetes Management and Research
- Cardiovascular Disease and Adiposity
- Lipid metabolism and biosynthesis
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
Sichuan University
2022-2025
State Key Laboratory of Biotherapy
2024
West China Hospital of Sichuan University
2022-2023
Wuhou District People's Hospital, Chengdu
2023
Background and Aims: Extrachromosomal circular DNAs (eccDNAs) are prevalent in cancer genomes emerge as a class of crucial yet less characterized oncogenic drivers. However, the structure, composition, genome-wide frequency, contribution eccDNAs HCC, one most fatal cancers, remain unexplored. In this study, we provide comprehensive characterization human HCC demonstrate an role microRNA (miRNA)-17-92-containing tumor progression. Approach Results: Using circle-sequencing method, identify...
Abstract To investigate the associations of composite dietary antioxidant index (CDAI) with risk cardiovascular disease (CVD) mortality among individuals type 2 diabetes (T2D). This prospective cohort study included 7551 patients T2D who participated in National Health and Nutrition Examination Survey (NHANES) from 1999 through 2018. Death statistics were gathered by connecting database to Index December 31, 2019. Multivariable Cox proportional hazards regression models utilized calculate...
Vascular endothelial cells, which make up the inner wall of blood arteries, are susceptible to damage from oxidative stress and apoptosis caused by hyperglycemia. According certain reports, noncoding RNAs involved in controlling apoptosis. ShenQi Compound (SQC), a traditional herbal remedy, has been successfully treating diabetic vascular disease China for more than 20 years. Although it is well established that SQC protects endothelium, molecular mechanism remains unknown. Goto-Kakizaki...
Type 2 diabetes (T2D) has emerged as a global epidemic, and conventional treatment approaches often face limitations in achieving long-term glycemic control preventing complications. Traditional Chinese Medicine (TCM) offers valuable alternative for managing T2D, with long history of effectively using herbal formulations clinical practice. However, the modular characteristics these herbs their specific mechanisms action remain poorly understood. To comprehensively investigate treating well...
Abstract Background: Vascular endothelial cell (VEC), which make up the inner wall of blood arteries, are susceptible to damage from oxidative stress and apoptosis caused by hyperglycemia. According certain reports, noncoding RNAs (ncRNAs) involved in controlling apoptosis. Shen Qi Compound (SQC), a traditional herbal remedy, has been successfully treating diabetic vascular disease China for more than 20 years. Although it is well established that SQC protects endothelium, molecular...