A5101699429- MRI in cancer diagnosis
- Cancer, Hypoxia, and Metabolism
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Genetic and phenotypic traits in livestock
- Nanoparticle-Based Drug Delivery
- Cancer-related molecular mechanisms research
- Dendrimers and Hyperbranched Polymers
- Body Contouring and Surgery
- Platelet Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- MicroRNA in disease regulation
- Meningioma and schwannoma management
- Bariatric Surgery and Outcomes
- Spinal Fractures and Fixation Techniques
- Brain Metastases and Treatment
- Diet and metabolism studies
- Uterine Myomas and Treatments
- Mesenchymal stem cell research
- Angiogenesis and VEGF in Cancer
- Atomic and Subatomic Physics Research
- Lanthanide and Transition Metal Complexes
- Management of metastatic bone disease
- Nerve injury and regeneration
Xiangyang Central Hospital
2020-2025
Tianjin Medical University General Hospital
2003-2025
Sichuan University
2020-2024
Longyan University
2023-2024
West China Hospital of Sichuan University
2020-2023
Chengde Medical University
2023
University of Jinan
2005-2022
Chengdu Second People's Hospital
2020
Wenzhou Central Hospital
2020
West China Second University Hospital of Sichuan University
2020
Background: More than one-fifth of the world’s population consumes Chinese cuisines regularly, but no evidence-based healthy diets fitting food culture are available for implementation. Methods: A multicenter, patient- and outcome assessor–blind, randomized feeding trial was conducted among 265 participants with 130 to 159 mm Hg baseline systolic blood pressure (SBP) 4 major (Shangdong, Huaiyang, Cantonese, Szechuan). After a 7-day run-in period on control diet matching usual local diets,...
Background and Aims: Extrachromosomal circular DNAs (eccDNAs) are prevalent in cancer genomes emerge as a class of crucial yet less characterized oncogenic drivers. However, the structure, composition, genome-wide frequency, contribution eccDNAs HCC, one most fatal cancers, remain unexplored. In this study, we provide comprehensive characterization human HCC demonstrate an role microRNA (miRNA)-17-92-containing tumor progression. Approach Results: Using circle-sequencing method, identify...
Ischemic stroke, accounting for 85% of stroke cases, leads to severe disabilities and increased mortality. Its global incidence rose by 87.55% from 1990 2019, posing significant health economic burdens. The BRICS-plus nations-Brazil, Russia, India, China, South Africa, five others-represent a large population, presenting unique public challenges. This study aims evaluate the epidemiological trends variations in burden ischemic across nations timely manner. Data on number, all-age rate,...
Background and Aims Endoplasmic reticulum (ER) stress is an adaptive response to excessive ER demand contributes the development of numerous diseases, including nonalcoholic fatty liver disease (NAFLD), which hallmarked by accumulation lipid within hepatocytes. However, underlying mechanisms remain elusive. MicroRNAs (miRNAs) play indispensable role in various responses, but their implications have not yet been systemically investigated. In this study, we identify a negative feedback loop...
The rapid emergence of SARS-CoV-2 variants concern, the complexity infection, and functional redundancy host factors, underscore an urgent need for broad-spectrum antivirals against continuous COVID-19 pandemic, with drug repurposing as a viable therapeutic strategy. Here we report potential RNA G-quadruplex (RG4)-targeting strategy entry. Combining bioinformatics, biochemical biophysical approaches, characterize existence RG4s in several factors. In silico screening followed by experimental...
Generation 5-poly(amidoamine) dendrimers pre-modified with folic acid and methotrexate (G5-FA-MTX) were used as templates for the synthesis of dendrimer-entrapped gold nanoparticles (Au DENPs). The synthesized [(Au0)50-G5-FA-MTX] DENPs able to target specifically inhibit growth cancer cells overexpressing high affinity receptors.
A multifunctional folic acid-targeted dendrimer-based nanoplatform was designed to have both Mn(ii) and 99mTc loaded via chelation. The formed displays good stability, cytocompatibility hemocompatibility in a given concentration range, can be used for targeted dual-mode single-photon emission computed tomography/magnetic resonance imaging of tumors.
Sesame peptides could be used to treat underlying diseases and a suitable carrier of nutrients. In this study, sesame were mainly prepared from SSM (sesame meal), the chelating ability different molecular weight peptide components calcium physical characterization chelates investigated. After that, weights verified by HPLC (high performance liquid chromatography), Zeta potential, PDI (polydispersity) SSMP meal peptides) determined. SSMP-Ca chelates, chelation rate SSMP-2 2) is 72.72 ± 0.17%....
To investigate the 3.0-Tesla (3 T) magnetic resonance imaging (MRI) characteristics of primary adnexal lesions for discriminating benign from malignant lesions.One hundred thirty-nine patients with pathologically proven masses referred 3 T MRI assessment preoperatively were included. Baseline characteristics, components, and conventional diffusion-weighted (DWI-MRI) signals recorded compared.There 22 ovarian cysts, 33 endometriomas, 43 tumors 42 tumors. When cyst endometrioma excluded, there...
To find specific magnetic resonance imaging (MRI) features to differentiate metastatic ovarian tumors from primary epithelial cancers. Eleven cases with and 26 malignant cancers were retrospectively studied. All such as patient characteristics, MRI findings biomarkers evaluated. The differences including laterality, configuration, uniformity of locules, diffusion weighted (DWI) signal solid components enhancement portions between compared by Fisher's exact test. Median age patients, the...