A5083448864- Neuroblastoma Research and Treatments
- Cell death mechanisms and regulation
- Childhood Cancer Survivors' Quality of Life
- Acute Myeloid Leukemia Research
- Immunotherapy and Immune Responses
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Child Abuse and Related Trauma
- Connective tissue disorders research
- Blood properties and coagulation
- Sarcoma Diagnosis and Treatment
- Testicular diseases and treatments
- Platelet Disorders and Treatments
- Colorectal Cancer Treatments and Studies
- Blood transfusion and management
- Cancer-related cognitive impairment studies
- Frailty in Older Adults
- Poisoning and overdose treatments
- PARP inhibition in cancer therapy
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Brain Metastases and Treatment
- Obstructive Sleep Apnea Research
- Genetic factors in colorectal cancer
- Angiogenesis and VEGF in Cancer
- Neutropenia and Cancer Infections
The University of Texas Health Science Center at San Antonio
2025
Geisinger Medical Center
2017-2020
University of Stirling
2008
University of Iowa
2004-2006
University of Iowa Hospitals and Clinics
2004
Royal London Hospital
2001
Middlesex University
2001
St. Mark's Hospital
2001
Introduction: Balance problems arising from cancer and its treatments can significantly impact daily functionality quality of life. Improving balance as part a treatment plan could result in better patient outcomes. Thus, the aim this study was to determine whether an integrative therapeutic yoga intervention improve heterogenous population survivors (CS). Methods: This is secondary analysis data 16-week feasibility where supplemented with psychosocial support maximize health-related life...
Here we describe the case of an infant incidentally diagnosed with congenital KMT2A-rearranged (KMT2A-r) B-cell ALL on Day Life 4. He received first dose intrathecal methotrexate DOL 5, and induction systemic therapy 6. demonstrated morphologic remission at end but had positive bone marrow. Minimal residual disease (MRD) was 1.4%. experienced isolated CNS after consolidation immunotherapy. At 8 months age he underwent hematopoietic stem cell transplantation (HSCT). 14 medullary relapse, 16...
Pediatric emergency RBC transfusions are often infused rapidly through 22-gauge (ga) or smaller needles catheters using hand-held syringes. Data relating needle size, unit age, and infusion rate needed to assess the risk of hemolysis hyperkalemia in this setting.Multiple simulated were performed during storage units. Aliquots from five units passed (18, 20, 22-25 ga) a syringe. Resulting plasma Hb K+ concentrations measured. Free levels used as measure needle-associated (NAH).Passage 18-ga...
Alterations in apoptotic mechanisms favoring cell survival may be vital for modifying tumor behavior. Survivin, an inhibitor of apoptosis, and caspase 8, a proapoptotic enzyme, are key players cellular mechanisms. We investigated whether the levels survivin 8 ratio between these 2 factors correlate with biology predicts outcome patients neuroblastoma. Survivin were quantified 38 primary specimens analyzed individually relation to each other. High expression high survivin:caspase ratios...
Glanzmann Thrombasthenia is a rare bleeding disorder causing life-threatening at menarche in the adolescent female. Bleeding often necessitates admission and multiple blood transfusions. Due to rarity of disease, management acute new-onset poses particular challenge. A 12-year-old menarchial female had persistent vaginal despite treatment modalities including aminocaproic acid, recombinant factor VIIa, intravenous estrogen, gonadotropin receptor hormone agonists. Although standard patients...
Glanzmann Thrombasthenia (GT) is a rare bleeding disorder causing life-threatening at menarche in the adolescent female. We describe 12-year-old menarchial female with persistent vaginal despite multiple treatment modalities including aminocaproic acid, recombinant factor VIIa (rFVIIa), intravenous estrogen, and gonadotropin receptor hormone agonists. Although standard of patients GT primarily rFVIIa, new-onset menstrual conjunction an immature hypothalamus-pituitary-ovarian axis often...
Ewing sarcoma is an aggressive malignancy of bone and soft tissue that accounts for ∼2% cases childhood cancer. It has been rarely reported as a secondary neoplasm. Data from the Childhood Cancer Survivor Study evaluated sarcomas in 5-year survivors We report 2 pediatric patients northeast Pennsylvania, who developed 9th rib within 5 years primary leukemia diagnoses.
73 Background: Childhood cancer patients have distinct health-related needs as they transition from patient to survivor and pediatric adult-based care. This study used the Transition Readiness Assessment Questionnaire (TRAQ) assess readiness compare variation in perceptions between patients, parents, physicians. Methods: The TRAQ was completed by ages 12 26 their parent oncologist at Geisinger Medical Center Sept. 2015 Dec. 2016. Surveys were scored according validated methods (min. 1, max....
Ewing sarcoma is an aggressive malignancy of bone and soft tissue that accounts for approximately 2% cases childhood cancer. It has been rarely reported as a secondary neoplasm. Data from the Childhood Cancer Survivor Study evaluated sarcomas in 5-year survivors We report two pediatric patients northeast Pennsylvania, who developed Sarcoma 9th rib within 5 years primary leukemia diagnoses.