A5045287115- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Mobile Health and mHealth Applications
- Family Support in Illness
- Cancer Treatment and Pharmacology
- Adolescent and Pediatric Healthcare
- Cancer-related cognitive impairment studies
- Telemedicine and Telehealth Implementation
- Neutropenia and Cancer Infections
- Frailty in Older Adults
- Chronic Disease Management Strategies
- Digital Mental Health Interventions
- Resilience and Mental Health
- Colorectal Cancer Screening and Detection
- Family Dynamics and Relationships
- Geriatric Care and Nursing Homes
- Family and Patient Care in Intensive Care Units
- Gastrointestinal Bleeding Diagnosis and Treatment
- Reproductive Health and Technologies
- Palliative Care and End-of-Life Issues
- Patient-Provider Communication in Healthcare
- Family and Disability Support Research
- Mental Health Research Topics
- Social Media in Health Education
- Technology Use by Older Adults
University of Strathclyde
2017-2025
Indiana University of Pennsylvania
2023-2024
University of Surrey
2016-2017
University Ucinf
2017
South Eastern Sydney Local Health District
2016
Sydney Sexual Health Centre
2013-2016
GlaxoSmithKline (United States)
2015
University of Dundee
2013
Karolinska Institutet
2013
Sydney Hospital
2013
While some evidence exists that real-time remote symptom monitoring devices can decrease morbidity and prevent unplanned admissions in oncology patients, overall, these studies have significant methodological weaknesses. The electronic Symptom Management using the Advanced System (ASyMS) Remote Technology (eSMART) study is designed to specifically address weaknesses with an appropriately powered, repeated-measures, parallel-group stratified randomised controlled trial of patients.A total...
To evaluate effects of remote monitoring adjuvant chemotherapy related side via the Advanced Symptom Management System (ASyMS) on symptom burden, quality life, supportive care needs, anxiety, self-efficacy, and work limitations.Multicentre, repeated measures, parallel group, evaluator masked, stratified randomised controlled trial.Twelve cancer centres in Austria, Greece, Norway, Republic Ireland, UK.829 patients with non-metastatic breast cancer, colorectal Hodgkin's disease, or...
Chemotherapy forms a core component of treatment for the majority patients with cancer. Recent changes in cancer services mean frequently receive such as outpatients and are often required to manage side effects at home without direct support from oncology health professionals. Information technology continues develop community; this study evaluated impact mobile phone-based advanced symptom management system (ASyMS©) on chemotherapy related toxicity lung, breast or colorectal One hundred...
Abstract Oncology patients undergoing cancer treatment experience an average of fifteen unrelieved symptoms that are highly variable in both their severity and distress. Recent advances Network Analysis (NA) provide a novel approach to gain insights into the complex nature co-occurring symptom clusters identify core symptoms. We present findings from first study used NA examine relationships among 38 common large sample oncology chemotherapy. Using two different models Pairwise Markov Random...
In remote communities, where frequent face-to-face contact with health professionals may be difficult, the ongoing review and management of symptoms – a fundamental part good palliative care can difficult to achieve. Telecare other developments in information technology are increasingly being sought as means addressing shifting population demographics rising demands on stretched services, help providing system which allows patients report their they happening. This one way enhancing symptom...
Interpretative phenomenological analysis (IPA) is uniquely positioned to enable health researchers and practitioners gain a rich understanding of the psychosocial experiences people living with conditions their family caregivers. The majority research in this field pertains acceptability, usability effectiveness supportive technology managing or treating conditions. Acknowledging ever-growing development application digital technologies support conditions, meaning such lives those using them...
A shift in cancer services from traditional tertiary care to delivered within communities has occurred (McCorkle et al., 2011). This increased the need for patients engage self-management activities prevent or reduce severity of numerous and often complex side effects involvement education can enhance patients' engagement self-care further guide important healthcare decision making when at home absence clinicians (Butow 2012).
We evaluated germline single nucleotide polymorphisms (SNPs) for association with overall survival (OS) in pazopanib- or sunitinib-treated patients advanced renal cell carcinoma (aRCC). The discovery analysis tested 27 SNPs within 13 genes from a phase III pazopanib trial (N=241, study 1). Suggestive associations were then pursued two independent datasets: (COMPARZ) comparing vs sunitinib (N=729, 2) and an observational of (N=89, 3). In 1, four showed nominally significant (P≤0.05) OS; these...
There has been an international shift in health care, which seen increasing focus and development of technological personalized at-home interventions that aim to improve outcomes patient-clinician communication. However, there is a notable lack empirical evidence describing the preparatory steps adapting implementing technology this kind across multiple countries clinical settings.This study aimed describe undertaken preparation multinational, multicenter randomized controlled trial (RCT)...
Digital health technology is valued as a tool to provide person-centred care and improve outcomes amongst people with cancer their family caregivers. Although the evidence date shows encouraging effectiveness, there limited knowledge regarding lived experience personal meaning of using supportive during treatment. The aim this study was explore experiences colorectal receiving chemotherapy digital symptom management caregivers.A longitudinal multi-perspective interpretative phenomenological...
Aims and objectives. To explore the experiences of 12 women with breast cancer, involved in a large longitudinal qualitative study designed to people cancer within first year following diagnosis. Background. understand further as chronic illness, this draws on biographically informed embodied perspectives illness. Design. Qualitative, study. Method. Interviews were conducted at three time‐points diagnosis cancer. Drawing constant comparative method, descriptive thematic approach data...
Technology is becoming an important medium for supporting patients in health care. However, successful application depends on user acceptability. The Advanced Symptom Management System (ASyMS) involves reporting cancer chemotherapy-related symptoms using mobile phone technology.The aim of this article was to report a study how young people were involved the development ASyMS Medical Research Council framework evaluating complex interventions.A convenience sample aged 13 18 years undergoing...
The overall objective was to evaluate the effectiveness of S-enantiomer roscovitine (inhibitor p34cdc2/cyclin B kinase) maintain bovine cumulus-oocyte complexes at germinal vesicle (GV) stage for extended times after removal from antral follicles without compromising subsequent maturation, fertilization and embryo development. Oocytes were cultured in 0, 12.5, 25 or 50 micromol/l S-roscovitine 24 h. Hoechst staining showed that maintained >90% oocytes GV inhibited gonadotropin-induced...
Effective symptom management is a critical component of cancer treatment. Computational tools that predict the course and severity these symptoms have potential to assist oncology clinicians personalize patient's treatment regimen more efficiently provide aggressive timely interventions. Three common inter-related in patients are depression, anxiety, sleep disturbance. In this paper, we elaborate on efficiency Support Vector Regression (SVR) Non-linear Canonical Correlation Analysis by...
The aim of this study is to explore the relationship that people with cancer and their family caregivers develop symptom management technology during chemotherapy. A longitudinal multi-perspective interpretative phenomenological approach was adopted. Data were collected using one-to-one in-depth interviews colorectal supportive digital health (n=3) (n=4) at two time points chemotherapy treatment. analyzed analysis followed COREQ guidelines. People can emotional bonds Digital be experienced...
There are approximately 6.5 million informal (unpaid) caregivers in the United Kingdom. Each caregiver plays a critical role society, supporting health and well-being of those who ill, disabled, or older need frequent support. Digital technologies becoming ubiquitous part everyday life for many, but little is known about real-world impact technology caring role, including abilities to address mental physical impacts caregiving.This study aims understand current future use caregivers, digital...