A5023919175- Neuroscience and Neuropharmacology Research
- Autophagy in Disease and Therapy
- Cannabis and Cannabinoid Research
- Pharmacological Receptor Mechanisms and Effects
- Alzheimer's disease research and treatments
- Memory and Neural Mechanisms
- Mitochondrial Function and Pathology
- Neuroendocrine regulation and behavior
- Neurotransmitter Receptor Influence on Behavior
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2024
Rutgers, The State University of New Jersey
2024
Johnson University
2024
Yeshiva University
1990
Abstract Neuronal connectivity is essential for adaptive brain responses and can be modulated by dendritic spine plasticity the intrinsic excitability of individual neurons. Dysregulation these processes lead to aberrant neuronal activity, which has been associated with numerous neurological disorders including autism, epilepsy, Alzheimer's disease. Nonetheless, molecular mechanisms underlying abnormal remain unclear. We previously found that serine/threonine kinase Microtubule Affinity...
Atherosclerosis (AS) is a major cause of mortality worldwide. Geniposide (GP) has lipolytic and anti-inflammatory effects widely administered for the treatment cardiovascular disease. There considerable evidence importance autophagy in system, GP can promote improve AS. However, underlying mechanism still unclear; network pharmacology molecular docking suggest that may play anti-atherosclerotic roles by regulating PI3K/Akt/mTOR pathway, which typical signal transduction approach. We further...